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Two consecutive phase II trials of biweekly oxaliplatin plus weekly 48-hour continuous infusion of nonmodulated high-dose 5-fluorouracil as first-line treatment for advanced colorectal cancer.
Abad A, Carrato A, Navarro M, Sastre J, Cervantes A, Antón A, Martinez-Villacampa M, Marcuello E, Massutí B, Aranda E, Manzano JL, Guallar JL, Diaz-Rubio E. Abad A, et al. Clin Colorectal Cancer. 2005 Mar;4(6):384-9. doi: 10.3816/ccc.2005.n.010. Clin Colorectal Cancer. 2005. PMID: 15807931 Clinical Trial.
A phase I, dose-finding study of irinotecan (CPT-11) short i.v. infusion combined with fixed dose of 5-fluorouracil (5-FU) protracted i.v. infusion in adult patients with advanced solid tumours.
Sastre J, Paz-Ares L, Carcas A, Alfonso R, Grávalos C, Frías J, Guerra P, Pronk L, Cortés-Funes H, Díaz-Rubio E. Sastre J, et al. Cancer Chemother Pharmacol. 2005 May;55(5):453-60. doi: 10.1007/s00280-004-0915-x. Epub 2004 Oct 26. Cancer Chemother Pharmacol. 2005. PMID: 15818508 Clinical Trial.
Irinotecan in combination with fluorouracil in a 48-hour continuous infusion as first-line chemotherapy for elderly patients with metastatic colorectal cancer: a Spanish Cooperative Group for the Treatment of Digestive Tumors study.
Sastre J, Marcuello E, Masutti B, Navarro M, Gil S, Antón A, Abad A, Aranda E, Maurel J, Valladares M, Maestu I, Carrato A, Vicent JM, Díaz-Rubio E; Cooperative Group for the Treatment of Digestive Tumors. Sastre J, et al. J Clin Oncol. 2005 May 20;23(15):3545-51. doi: 10.1200/JCO.2005.03.004. J Clin Oncol. 2005. PMID: 15908665 Clinical Trial.
Chemotherapy for gastric cancer.
Sastre J, Garcia-Saenz JA, Diaz-Rubio E. Sastre J, et al. World J Gastroenterol. 2006 Jan 14;12(2):204-13. doi: 10.3748/wjg.v12.i2.204. World J Gastroenterol. 2006. PMID: 16482619 Free PMC article. Review.
New target-based agents involve new clinical trial designs.
Bueno Muíño C, García-Sáenz JA, López Tarruella S, Rodríguez Lajustica L, Díaz-Rubio E. Bueno Muíño C, et al. Clin Transl Oncol. 2006 Aug;8(8):581-7. doi: 10.1007/s12094-006-0063-3. Clin Transl Oncol. 2006. PMID: 16952846 Review.
325 results