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228 results

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Page 1
Assessment of metabolic stability using the rainbow trout (Oncorhynchus mykiss) liver S9 fraction.
Johanning K, Hancock G, Escher B, Adekola A, Bernhard MJ, Cowan-Ellsberry C, Domoradzki J, Dyer S, Eickhoff C, Embry M, Erhardt S, Fitzsimmons P, Halder M, Hill J, Holden D, Johnson R, Rutishauser S, Segner H, Schultz I, Nichols J. Johanning K, et al. Among authors: segner h. Curr Protoc Toxicol. 2012 Aug;Chapter 14:Unit 14.10.1-28. doi: 10.1002/0471140856.tx1410s53. Curr Protoc Toxicol. 2012. PMID: 22896006
Reliability of In Vitro Methods Used to Measure Intrinsic Clearance of Hydrophobic Organic Chemicals by Rainbow Trout: Results of an International Ring Trial.
Nichols J, Fay K, Bernhard MJ, Bischof I, Davis J, Halder M, Hu J, Johanning K, Laue H, Nabb D, Schlechtriem C, Segner H, Swintek J, Weeks J, Embry M. Nichols J, et al. Among authors: segner h. Toxicol Sci. 2018 Aug 1;164(2):563-575. doi: 10.1093/toxsci/kfy113. Toxicol Sci. 2018. PMID: 29767801 Free PMC article.
Protein and lipid binding parameters in rainbow trout (Oncorhynchus mykiss) blood and liver fractions to extrapolate from an in vitro metabolic degradation assay to in vivo bioaccumulation potential of hydrophobic organic chemicals.
Escher BI, Cowan-Ellsberry CE, Dyer S, Embry MR, Erhardt S, Halder M, Kwon JH, Johanning K, Oosterwijk MT, Rutishauser S, Segner H, Nichols J. Escher BI, et al. Among authors: segner h. Chem Res Toxicol. 2011 Jul 18;24(7):1134-43. doi: 10.1021/tx200114y. Epub 2011 Jun 8. Chem Res Toxicol. 2011. PMID: 21604782
An International Perspective on the Tools and Concepts for Effluent Toxicity Assessments in the Context of Animal Alternatives: Reduction in Vertebrate Use.
Norberg-King TJ, Embry MR, Belanger SE, Braunbeck T, Butler JD, Dorn PB, Farr B, Guiney PD, Hughes SA, Jeffries M, Journel R, Lèonard M, McMaster M, Oris JT, Ryder K, Segner H, Senac T, Van Der Kraak G, Whale G, Wilson P. Norberg-King TJ, et al. Among authors: segner h. Environ Toxicol Chem. 2018 Nov;37(11):2745-2757. doi: 10.1002/etc.4259. Environ Toxicol Chem. 2018. PMID: 30359486 Free PMC article. Review.
Cell-based data to predict the toxicity of chemicals to fish. Commentary on the manuscript by Rodrigues et al., 2019. Cell-based assays seem not to accurately predict fish short-term toxicity of pesticides. Environmental Pollution 252:476-482.
Schirmer K, Stadnicka-Michalak J, Belanger SE, Blaha L, Bols NC, Dyer SD, Embry MR, Fischer M, Halder M, Hermens J, Hultman MT, Kramer N, Laue H, Lee LE, Lillicrap A, Natsch A, Segner H, Tanneberger K, Tollefsen KE, Werner I, Witters H, Zupanic A. Schirmer K, et al. Among authors: segner h. Environ Pollut. 2019 Nov;254(Pt B):113060. doi: 10.1016/j.envpol.2019.113060. Environ Pollut. 2019. PMID: 31540601 No abstract available.
228 results