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Page 1
Therapeutic effect of γ-secretase inhibition in KrasG12V-driven non-small cell lung carcinoma by derepression of DUSP1 and inhibition of ERK.
Maraver A, Fernández-Marcos PJ, Herranz D, Muñoz-Martin M, Gomez-Lopez G, Cañamero M, Mulero F, Megías D, Sanchez-Carbayo M, Shen J, Sanchez-Cespedes M, Palomero T, Ferrando A, Serrano M. Maraver A, et al. Cancer Cell. 2012 Aug 14;22(2):222-34. doi: 10.1016/j.ccr.2012.06.014. Cancer Cell. 2012. PMID: 22897852 Free PMC article.
Pten positively regulates brown adipose function, energy expenditure, and longevity.
Ortega-Molina A, Efeyan A, Lopez-Guadamillas E, Muñoz-Martin M, Gómez-López G, Cañamero M, Mulero F, Pastor J, Martinez S, Romanos E, Mar Gonzalez-Barroso M, Rial E, Valverde AM, Bischoff JR, Serrano M. Ortega-Molina A, et al. Cell Metab. 2012 Mar 7;15(3):382-94. doi: 10.1016/j.cmet.2012.02.001. Cell Metab. 2012. PMID: 22405073 Free article.
SIRT1 promotes thyroid carcinogenesis driven by PTEN deficiency.
Herranz D, Maraver A, Cañamero M, Gómez-López G, Inglada-Pérez L, Robledo M, Castelblanco E, Matias-Guiu X, Serrano M. Herranz D, et al. Oncogene. 2013 Aug 22;32(34):4052-6. doi: 10.1038/onc.2012.407. Epub 2012 Sep 17. Oncogene. 2013. PMID: 22986535
Programmed cell senescence during mammalian embryonic development.
Muñoz-Espín D, Cañamero M, Maraver A, Gómez-López G, Contreras J, Murillo-Cuesta S, Rodríguez-Baeza A, Varela-Nieto I, Ruberte J, Collado M, Serrano M. Muñoz-Espín D, et al. Cell. 2013 Nov 21;155(5):1104-18. doi: 10.1016/j.cell.2013.10.019. Epub 2013 Nov 14. Cell. 2013. PMID: 24238962 Free article.
Lineage-restricted function of the pluripotency factor NANOG in stratified epithelia.
Piazzolla D, Palla AR, Pantoja C, Cañamero M, de Castro IP, Ortega S, Gómez-López G, Dominguez O, Megías D, Roncador G, Luque-Garcia JL, Fernandez-Tresguerres B, Fernandez AF, Fraga MF, Rodriguez-Justo M, Manzanares M, Sánchez-Carbayo M, García-Pedrero JM, Rodrigo JP, Malumbres M, Serrano M. Piazzolla D, et al. Nat Commun. 2014 Jun 30;5:4226. doi: 10.1038/ncomms5226. Nat Commun. 2014. PMID: 24979572 Free article.
RAB7 controls melanoma progression by exploiting a lineage-specific wiring of the endolysosomal pathway.
Alonso-Curbelo D, Riveiro-Falkenbach E, Pérez-Guijarro E, Cifdaloz M, Karras P, Osterloh L, Megías D, Cañón E, Calvo TG, Olmeda D, Gómez-López G, Graña O, Sánchez-Arévalo Lobo VJ, Pisano DG, Wang HW, Ortiz-Romero P, Tormo D, Hoek K, Rodríguez-Peralto JL, Joyce JA, Soengas MS. Alonso-Curbelo D, et al. Cancer Cell. 2014 Jul 14;26(1):61-76. doi: 10.1016/j.ccr.2014.04.030. Epub 2014 Jun 26. Cancer Cell. 2014. PMID: 24981740 Free article.
Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment.
Sainz B Jr, Alcala S, Garcia E, Sanchez-Ripoll Y, Azevedo MM, Cioffi M, Tatari M, Miranda-Lorenzo I, Hidalgo M, Gomez-Lopez G, Cañamero M, Erkan M, Kleeff J, García-Silva S, Sancho P, Hermann PC, Heeschen C. Sainz B Jr, et al. Gut. 2015 Dec;64(12):1921-35. doi: 10.1136/gutjnl-2014-308935. Epub 2015 Apr 3. Gut. 2015. PMID: 25841238
108 results