Fuchs JR - Search Results

1

Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines.

Bill MA, Nicholas C, Mace TA, Etter JP, Li C, Schwartz EB, Fuchs JR, Young GS, Lin L, Lin J, He L, Phelps M, Li PK, Lesinski GB. Bill MA, et al. Among authors: fuchs jr. PLoS One. 2012;7(8):e40724. doi: 10.1371/journal.pone.0040724. Epub 2012 Aug 10. PLoS One. 2012. PMID: 22899991 Free PMC article.

2

Modulation of DNA methylation by a sesquiterpene lactone parthenolide.

Liu Z, Liu S, Xie Z, Pavlovicz RE, Wu J, Chen P, Aimiuwu J, Pang J, Bhasin D, Neviani P, Fuchs JR, Plass C, Li PK, Li C, Huang TH, Wu LC, Rush L, Wang H, Perrotti D, Marcucci G, Chan KK. Liu Z, et al. Among authors: fuchs jr. J Pharmacol Exp Ther. 2009 May;329(2):505-14. doi: 10.1124/jpet.108.147934. Epub 2009 Feb 6. J Pharmacol Exp Ther. 2009. PMID: 19201992 Free PMC article.

3

Structure-activity relationship studies of curcumin analogues.

Fuchs JR, Pandit B, Bhasin D, Etter JP, Regan N, Abdelhamid D, Li C, Lin J, Li PK. Fuchs JR, et al. Bioorg Med Chem Lett. 2009 Apr 1;19(7):2065-9. doi: 10.1016/j.bmcl.2009.01.104. Epub 2009 Feb 5. Bioorg Med Chem Lett. 2009. PMID: 19249204

4

New structural analogues of curcumin exhibit potent growth suppressive activity in human colorectal carcinoma cells.

Cen L, Hutzen B, Ball S, DeAngelis S, Chen CL, Fuchs JR, Li C, Li PK, Lin J. Cen L, et al. Among authors: fuchs jr. BMC Cancer. 2009 Mar 30;9:99. doi: 10.1186/1471-2407-9-99. BMC Cancer. 2009. PMID: 19331692 Free PMC article.

5

Curcumin analogues exhibit enhanced growth suppressive activity in human pancreatic cancer cells.

Friedman L, Lin L, Ball S, Bekaii-Saab T, Fuchs J, Li PK, Li C, Lin J. Friedman L, et al. Anticancer Drugs. 2009 Jul;20(6):444-9. doi: 10.1097/CAD.0b013e32832afc04. Anticancer Drugs. 2009. PMID: 19384191 Free PMC article.

6

New curcumin analogues exhibit enhanced growth-suppressive activity and inhibit AKT and signal transducer and activator of transcription 3 phosphorylation in breast and prostate cancer cells.

Lin L, Hutzen B, Ball S, Foust E, Sobo M, Deangelis S, Pandit B, Friedman L, Li C, Li PK, Fuchs J, Lin J. Lin L, et al. Cancer Sci. 2009 Sep;100(9):1719-27. doi: 10.1111/j.1349-7006.2009.01220.x. Epub 2009 May 18. Cancer Sci. 2009. PMID: 19558577 Free PMC article.

7

Curcumin induces proapoptotic effects against human melanoma cells and modulates the cellular response to immunotherapeutic cytokines.

Bill MA, Bakan C, Benson DM Jr, Fuchs J, Young G, Lesinski GB. Bill MA, et al. Among authors: fuchs j. Mol Cancer Ther. 2009 Sep;8(9):2726-35. doi: 10.1158/1535-7163.MCT-09-0377. Epub 2009 Sep 1. Mol Cancer Ther. 2009. PMID: 19723881 Free PMC article.

8

Novel STAT3 phosphorylation inhibitors exhibit potent growth-suppressive activity in pancreatic and breast cancer cells.

Lin L, Hutzen B, Zuo M, Ball S, Deangelis S, Foust E, Pandit B, Ihnat MA, Shenoy SS, Kulp S, Li PK, Li C, Fuchs J, Lin J. Lin L, et al. Cancer Res. 2010 Mar 15;70(6):2445-54. doi: 10.1158/0008-5472.CAN-09-2468. Epub 2010 Mar 9. Cancer Res. 2010. PMID: 20215512 Free PMC article.

9

The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity.

Bill MA, Fuchs JR, Li C, Yui J, Bakan C, Benson DM Jr, Schwartz EB, Abdelhamid D, Lin J, Hoyt DG, Fossey SL, Young GS, Carson WE 3rd, Li PK, Lesinski GB. Bill MA, et al. Among authors: fuchs jr. Mol Cancer. 2010 Jun 25;9:165. doi: 10.1186/1476-4598-9-165. Mol Cancer. 2010. PMID: 20576164 Free PMC article.

10

A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells.

Lin L, Deangelis S, Foust E, Fuchs J, Li C, Li PK, Schwartz EB, Lesinski GB, Benson D, Lü J, Hoyt D, Lin J. Lin L, et al. Mol Cancer. 2010 Aug 16;9:217. doi: 10.1186/1476-4598-9-217. Mol Cancer. 2010. PMID: 20712901 Free PMC article.

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