Svensson R - Search Results

1

The value of selected in vitro and in silico methods to predict acute oral toxicity in a regulatory context: results from the European Project ACuteTox.

Prieto P, Kinsner-Ovaskainen A, Stanzel S, Albella B, Artursson P, Campillo N, Cecchelli R, Cerrato L, Díaz L, Di Consiglio E, Guerra A, Gombau L, Herrera G, Honegger P, Landry C, O'Connor JE, Páez JA, Quintas G, Svensson R, Turco L, Zurich MG, Zurbano MJ, Kopp-Schneider A. Prieto P, et al. Among authors: svensson r. Toxicol In Vitro. 2013 Jun;27(4):1357-76. doi: 10.1016/j.tiv.2012.07.013. Epub 2012 Aug 16. Toxicol In Vitro. 2013. PMID: 22922246

2

In vitro and in silico strategies to identify OATP1B1 inhibitors and predict clinical drug-drug interactions.

Karlgren M, Ahlin G, Bergström CA, Svensson R, Palm J, Artursson P. Karlgren M, et al. Among authors: svensson r. Pharm Res. 2012 Feb;29(2):411-26. doi: 10.1007/s11095-011-0564-9. Epub 2011 Aug 23. Pharm Res. 2012. PMID: 21861202 Free PMC article.

3

Anti-Rift Valley fever virus activity in vitro, pre-clinical pharmacokinetics and oral bioavailability of benzavir-2, a broad-acting antiviral compound.

Islam MK, Strand M, Saleeb M, Svensson R, Baranczewski P, Artursson P, Wadell G, Ahlm C, Elofsson M, Evander M. Islam MK, et al. Among authors: svensson r. Sci Rep. 2018 Jan 31;8(1):1925. doi: 10.1038/s41598-018-20362-9. Sci Rep. 2018. PMID: 29386590 Free PMC article.

4

Optimizing solubility and permeability of a biopharmaceutics classification system (BCS) class 4 antibiotic drug using lipophilic fragments disturbing the crystal lattice.

Tehler U, Fagerberg JH, Svensson R, Larhed M, Artursson P, Bergström CA. Tehler U, et al. Among authors: svensson r. J Med Chem. 2013 Mar 28;56(6):2690-4. doi: 10.1021/jm301721e. Epub 2013 Mar 19. J Med Chem. 2013. PMID: 23432334 Free article.

5

Preclinical characterization of acyl sulfonimidamides: potential carboxylic acid bioisosteres with tunable properties.

Borhade SR, Svensson R, Brandt P, Artursson P, Arvidsson PI, Sandström A. Borhade SR, et al. Among authors: svensson r. ChemMedChem. 2015 Mar;10(3):455-60. doi: 10.1002/cmdc.201402497. Epub 2015 Jan 28. ChemMedChem. 2015. PMID: 25630705

6

Monitoring drug-target interactions through target engagement-mediated amplification on arrays and in situ.

Al-Amin RA, Johansson L, Abdurakhmanov E, Landegren N, Löf L, Arngården L, Blokzijl A, Svensson R, Hammond M, Lönn P, Haybaeck J, Kamali-Moghaddam M, Jensen AJ, Danielson UH, Artursson P, Lundbäck T, Landegren U. Al-Amin RA, et al. Among authors: svensson r. Nucleic Acids Res. 2022 Dec 9;50(22):e129. doi: 10.1093/nar/gkac842. Nucleic Acids Res. 2022. PMID: 36189884 Free PMC article.

7

Achiral pyrazinone-based inhibitors of the hepatitis C virus NS3 protease and drug-resistant variants with elongated substituents directed toward the S2 pocket.

Gising J, Belfrage AK, Alogheli H, Ehrenberg A, Åkerblom E, Svensson R, Artursson P, Karlén A, Danielson UH, Larhed M, Sandström A. Gising J, et al. Among authors: svensson r. J Med Chem. 2014 Mar 13;57(5):1790-801. doi: 10.1021/jm301887f. Epub 2013 Apr 2. J Med Chem. 2014. PMID: 23517538

8

Vinylated linear P2 pyrimidinyloxyphenylglycine based inhibitors of the HCV NS3/4A protease and corresponding macrocycles.

Lampa A, Alogheli H, Ehrenberg AE, Åkerblom E, Svensson R, Artursson P, Danielson UH, Karlén A, Sandström A. Lampa A, et al. Among authors: svensson r. Bioorg Med Chem. 2014 Dec 1;22(23):6595-6615. doi: 10.1016/j.bmc.2014.10.010. Bioorg Med Chem. 2014. PMID: 25456385

9

Novel Peptidomimetic Hepatitis C Virus NS3/4A Protease Inhibitors Spanning the P2-P1' Region.

Lampa AK, Bergman SM, Gustafsson SS, Alogheli H, Akerblom EB, Lindeberg GG, Svensson RM, Artursson P, Danielson UH, Karlén A, Sandström A. Lampa AK, et al. ACS Med Chem Lett. 2013 Aug 2;5(3):249-54. doi: 10.1021/ml400217r. eCollection 2014 Mar 13. ACS Med Chem Lett. 2013. PMID: 24900813 Free PMC article.

10

Exploration and pharmacokinetic profiling of phenylalanine based carbamates as novel substance p 1-7 analogues.

Fransson R, Nordvall G, Bylund J, Carlsson-Jonsson A, Kratz JM, Svensson R, Artursson P, Hallberg M, Sandström A. Fransson R, et al. Among authors: svensson r. ACS Med Chem Lett. 2014 Oct 29;5(12):1272-7. doi: 10.1021/ml5002954. eCollection 2014 Dec 11. ACS Med Chem Lett. 2014. PMID: 25516784 Free PMC article.

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