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SMAD4 Loss Is Associated with Cetuximab Resistance and Induction of MAPK/JNK Activation in Head and Neck Cancer Cells.
Ozawa H, Ranaweera RS, Izumchenko E, Makarev E, Zhavoronkov A, Fertig EJ, Howard JD, Markovic A, Bedi A, Ravi R, Perez J, Le QT, Kong CS, Jordan RC, Wang H, Kang H, Quon H, Sidransky D, Chung CH. Ozawa H, et al. Among authors: bedi a. Clin Cancer Res. 2017 Sep 1;23(17):5162-5175. doi: 10.1158/1078-0432.CCR-16-1686. Epub 2017 May 18. Clin Cancer Res. 2017. PMID: 28522603 Free PMC article.
Bifunctional immune checkpoint-targeted antibody-ligand traps that simultaneously disable TGFβ enhance the efficacy of cancer immunotherapy.
Ravi R, Noonan KA, Pham V, Bedi R, Zhavoronkov A, Ozerov IV, Makarev E, V Artemov A, Wysocki PT, Mehra R, Nimmagadda S, Marchionni L, Sidransky D, Borrello IM, Izumchenko E, Bedi A. Ravi R, et al. Among authors: bedi a, bedi r. Nat Commun. 2018 Feb 21;9(1):741. doi: 10.1038/s41467-017-02696-6. Nat Commun. 2018. PMID: 29467463 Free PMC article.
Patient-derived xenografts as tools in pharmaceutical development.
Izumchenko E, Meir J, Bedi A, Wysocki PT, Hoque MO, Sidransky D. Izumchenko E, et al. Among authors: bedi a. Clin Pharmacol Ther. 2016 Jun;99(6):612-21. doi: 10.1002/cpt.354. Epub 2016 Mar 9. Clin Pharmacol Ther. 2016. PMID: 26874468 Review.
NF-kappaB in cancer--a friend turned foe.
Ravi R, Bedi A. Ravi R, et al. Among authors: bedi a. Drug Resist Updat. 2004 Feb;7(1):53-67. doi: 10.1016/j.drup.2004.01.003. Drug Resist Updat. 2004. PMID: 15072771 Review.
584 results