Bots M - Search Results

1

NKT cell adjuvant-based tumor vaccine for treatment of myc oncogene-driven mouse B-cell lymphoma.

Mattarollo SR, West AC, Steegh K, Duret H, Paget C, Martin B, Matthews GM, Shortt J, Chesi M, Bergsagel PL, Bots M, Zuber J, Lowe SW, Johnstone RW, Smyth MJ. Mattarollo SR, et al. Among authors: bots m. Blood. 2012 Oct 11;120(15):3019-29. doi: 10.1182/blood-2012-04-426643. Epub 2012 Aug 28. Blood. 2012. PMID: 22932803 Free PMC article.

2

The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy.

Ellis L, Bots M, Lindemann RK, Bolden JE, Newbold A, Cluse LA, Scott CL, Strasser A, Atadja P, Lowe SW, Johnstone RW. Ellis L, et al. Among authors: bots m. Blood. 2009 Jul 9;114(2):380-93. doi: 10.1182/blood-2008-10-182758. Epub 2009 Apr 21. Blood. 2009. PMID: 19383971 Free PMC article.

3

Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors.

Bots M, Verbrugge I, Martin BP, Salmon JM, Ghisi M, Baker A, Stanley K, Shortt J, Ossenkoppele GJ, Zuber J, Rappaport AR, Atadja P, Lowe SW, Johnstone RW. Bots M, et al. Blood. 2014 Feb 27;123(9):1341-52. doi: 10.1182/blood-2013-03-488114. Epub 2014 Jan 10. Blood. 2014. PMID: 24415537 Free PMC article.

4

Rational combinations using HDAC inhibitors.

Bots M, Johnstone RW. Bots M, et al. Clin Cancer Res. 2009 Jun 15;15(12):3970-7. doi: 10.1158/1078-0432.CCR-08-2786. Epub 2009 Jun 9. Clin Cancer Res. 2009. PMID: 19509171 Review.

5

Antitumor activities and on-target toxicities mediated by a TRAIL receptor agonist following cotreatment with panobinostat.

Martin BP, Frew AJ, Bots M, Fox S, Long F, Takeda K, Yagita H, Atadja P, Smyth MJ, Johnstone RW. Martin BP, et al. Among authors: bots m. Int J Cancer. 2011 Jun 1;128(11):2735-47. doi: 10.1002/ijc.25594. Epub 2010 Oct 13. Int J Cancer. 2011. PMID: 20715169

6

The mTORC1 inhibitor everolimus prevents and treats Eμ-Myc lymphoma by restoring oncogene-induced senescence.

Wall M, Poortinga G, Stanley KL, Lindemann RK, Bots M, Chan CJ, Bywater MJ, Kinross KM, Astle MV, Waldeck K, Hannan KM, Shortt J, Smyth MJ, Lowe SW, Hannan RD, Pearson RB, Johnstone RW, McArthur GA. Wall M, et al. Among authors: bots m. Cancer Discov. 2013 Jan;3(1):82-95. doi: 10.1158/2159-8290.CD-12-0404. Epub 2012 Dec 14. Cancer Discov. 2013. PMID: 23242809 Free PMC article.

7

Promises and challenges of anticancer drugs that target the epigenome.

Verbrugge I, Johnstone RW, Bots M. Verbrugge I, et al. Among authors: bots m. Epigenomics. 2011 Oct;3(5):547-65. doi: 10.2217/epi.11.82. Epigenomics. 2011. PMID: 22126246 Review.

8

Combining the differentiating effect of panobinostat with the apoptotic effect of arsenic trioxide leads to significant survival benefit in a model of t(8;21) acute myeloid leukemia.

Salmon JM, Bots M, Vidacs E, Stanley KL, Atadja P, Zuber J, Johnstone RW. Salmon JM, et al. Among authors: bots m. Clin Epigenetics. 2015 Jan 22;7(1):2. doi: 10.1186/s13148-014-0034-4. eCollection 2015. Clin Epigenetics. 2015. PMID: 25628765 Free PMC article.

9

Detection of apoptotic cells using propidium iodide staining.

Newbold A, Martin BP, Cullinane C, Bots M. Newbold A, et al. Among authors: bots m. Cold Spring Harb Protoc. 2014 Nov 3;2014(11):1202-6. doi: 10.1101/pdb.prot082545. Cold Spring Harb Protoc. 2014. PMID: 25368311

10

Measuring apoptosis in mammals in vivo.

Newbold A, Martin BP, Cullinane C, Bots M. Newbold A, et al. Among authors: bots m. Cold Spring Harb Protoc. 2014 Nov 3;2014(11):1125-7. doi: 10.1101/pdb.top070417. Cold Spring Harb Protoc. 2014. PMID: 25368316

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