Huang GC - Search Results

1

Human β-cell killing by autoreactive preproinsulin-specific CD8 T cells is predominantly granule-mediated with the potency dependent upon T-cell receptor avidity.

Knight RR, Kronenberg D, Zhao M, Huang GC, Eichmann M, Bulek A, Wooldridge L, Cole DK, Sewell AK, Peakman M, Skowera A. Knight RR, et al. Among authors: huang gc. Diabetes. 2013 Jan;62(1):205-13. doi: 10.2337/db12-0315. Epub 2012 Aug 30. Diabetes. 2013. PMID: 22936177 Free PMC article.

2

CTLs are targeted to kill beta cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope.

Skowera A, Ellis RJ, Varela-Calviño R, Arif S, Huang GC, Van-Krinks C, Zaremba A, Rackham C, Allen JS, Tree TI, Zhao M, Dayan CM, Sewell AK, Unger WW, Drijfhout JW, Ossendorp F, Roep BO, Peakman M. Skowera A, et al. Among authors: huang gc. J Clin Invest. 2008 Oct;118(10):3390-402. doi: 10.1172/JCI35449. J Clin Invest. 2008. PMID: 18802479 Free PMC article.

3

A distinct immunogenic region of glutamic acid decarboxylase 65 is naturally processed and presented by human islet cells to cytotoxic CD8 T cells.

Knight RR, Dolton G, Kronenberg-Versteeg D, Eichmann M, Zhao M, Huang GC, Beck K, Cole DK, Sewell AK, Skowera A, Peakman M. Knight RR, et al. Among authors: huang gc. Clin Exp Immunol. 2015 Jan;179(1):100-7. doi: 10.1111/cei.12436. Clin Exp Immunol. 2015. PMID: 25112375 Free PMC article.

4

Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell death.

Arif S, Moore F, Marks K, Bouckenooghe T, Dayan CM, Planas R, Vives-Pi M, Powrie J, Tree T, Marchetti P, Huang GC, Gurzov EN, Pujol-Borrell R, Eizirik DL, Peakman M. Arif S, et al. Among authors: huang gc. Diabetes. 2011 Aug;60(8):2112-9. doi: 10.2337/db10-1643. Epub 2011 Jun 9. Diabetes. 2011. PMID: 21659501 Free PMC article.

5

Conversion of non-endocrine human pancreatic cells to insulin-producing cells for treatment of diabetes.

Zhao M, Huang GC. Zhao M, et al. Among authors: huang gc. Methods Mol Biol. 2012;806:73-85. doi: 10.1007/978-1-61779-367-7_6. Methods Mol Biol. 2012. PMID: 22057446

6

Amelioration of streptozotocin-induced diabetes in mice with cells derived from human marrow stromal cells.

Zhao M, Amiel SA, Ajami S, Jiang J, Rela M, Heaton N, Huang GC. Zhao M, et al. Among authors: huang gc. PLoS One. 2008 Jul 16;3(7):e2666. doi: 10.1371/journal.pone.0002666. PLoS One. 2008. PMID: 18628974 Free PMC article.

7

Ex vivo expanded human regulatory T cells delay islet allograft rejection via inhibiting islet-derived monocyte chemoattractant protein-1 production in CD34+ stem cells-reconstituted NOD-scid IL2rγnull mice.

Xiao F, Ma L, Zhao M, Huang G, Mirenda V, Dorling A, Lechler R, Lombardi G. Xiao F, et al. PLoS One. 2014 Mar 3;9(3):e90387. doi: 10.1371/journal.pone.0090387. eCollection 2014. PLoS One. 2014. PMID: 24594640 Free PMC article.

8

GLP-1 and glucagon secretion from a pancreatic neuroendocrine tumor causing diabetes and hyperinsulinemic hypoglycemia.

Roberts RE, Zhao M, Whitelaw BC, Ramage J, Diaz-Cano S, le Roux CW, Quaglia A, Huang GC, Aylwin SJ. Roberts RE, et al. Among authors: huang gc. J Clin Endocrinol Metab. 2012 Sep;97(9):3039-45. doi: 10.1210/jc.2011-2005. Epub 2012 Jul 6. J Clin Endocrinol Metab. 2012. PMID: 22774207

9

C3aR and C5aR1 act as key regulators of human and mouse β-cell function.

Atanes P, Ruz-Maldonado I, Pingitore A, Hawkes R, Liu B, Zhao M, Huang GC, Persaud SJ, Amisten S. Atanes P, et al. Among authors: huang gc. Cell Mol Life Sci. 2018 Feb;75(4):715-726. doi: 10.1007/s00018-017-2655-1. Epub 2017 Sep 18. Cell Mol Life Sci. 2018. PMID: 28921001 Free PMC article.

10

Evidence for the presence of stem cell-like progenitor cells in human adult pancreas.

Zhao M, Amiel SA, Christie MR, Muiesan P, Srinivasan P, Littlejohn W, Rela M, Arno M, Heaton N, Huang GC. Zhao M, et al. Among authors: huang gc. J Endocrinol. 2007 Dec;195(3):407-14. doi: 10.1677/JOE-07-0436. J Endocrinol. 2007. PMID: 18000303

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