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Page 1
How actin initiates the motor activity of Myosin.
Llinas P, Isabet T, Song L, Ropars V, Zong B, Benisty H, Sirigu S, Morris C, Kikuti C, Safer D, Sweeney HL, Houdusse A. Llinas P, et al. Among authors: ropars v. Dev Cell. 2015 May 26;33(4):401-12. doi: 10.1016/j.devcel.2015.03.025. Epub 2015 Apr 30. Dev Cell. 2015. PMID: 25936506 Free PMC article.
Force-producing ADP state of myosin bound to actin.
Wulf SF, Ropars V, Fujita-Becker S, Oster M, Hofhaus G, Trabuco LG, Pylypenko O, Sweeney HL, Houdusse AM, Schröder RR. Wulf SF, et al. Among authors: ropars v. Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):E1844-52. doi: 10.1073/pnas.1516598113. Epub 2016 Mar 14. Proc Natl Acad Sci U S A. 2016. PMID: 26976594 Free PMC article.
The myosin X motor is optimized for movement on actin bundles.
Ropars V, Yang Z, Isabet T, Blanc F, Zhou K, Lin T, Liu X, Hissier P, Samazan F, Amigues B, Yang ED, Park H, Pylypenko O, Cecchini M, Sindelar CV, Sweeney HL, Houdusse A. Ropars V, et al. Nat Commun. 2016 Sep 1;7:12456. doi: 10.1038/ncomms12456. Nat Commun. 2016. PMID: 27580874 Free PMC article.
Highly selective inhibition of myosin motors provides the basis of potential therapeutic application.
Sirigu S, Hartman JJ, Planelles-Herrero VJ, Ropars V, Clancy S, Wang X, Chuang G, Qian X, Lu PP, Barrett E, Rudolph K, Royer C, Morgan BP, Stura EA, Malik FI, Houdusse AM. Sirigu S, et al. Among authors: ropars v. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7448-E7455. doi: 10.1073/pnas.1609342113. Epub 2016 Nov 4. Proc Natl Acad Sci U S A. 2016. PMID: 27815532 Free PMC article.
Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining.
Ropars V, Drevet P, Legrand P, Baconnais S, Amram J, Faure G, Márquez JA, Piétrement O, Guerois R, Callebaut I, Le Cam E, Revy P, de Villartay JP, Charbonnier JB. Ropars V, et al. Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12663-8. doi: 10.1073/pnas.1100758108. Epub 2011 Jul 18. Proc Natl Acad Sci U S A. 2011. PMID: 21768349 Free PMC article.
Cryo-EM of NHEJ supercomplexes provides insights into DNA repair.
Chaplin AK, Hardwick SW, Stavridi AK, Buehl CJ, Goff NJ, Ropars V, Liang S, De Oliveira TM, Chirgadze DY, Meek K, Charbonnier JB, Blundell TL. Chaplin AK, et al. Among authors: ropars v. Mol Cell. 2021 Aug 19;81(16):3400-3409.e3. doi: 10.1016/j.molcel.2021.07.005. Epub 2021 Aug 4. Mol Cell. 2021. PMID: 34352203 Free PMC article.
39 results