Mee C - Search Results

1

Theoretical studies of chemical reactivity of metabolically activated forms of aromatic amines toward DNA.

Shamovsky I, Ripa L, Blomberg N, Eriksson LA, Hansen P, Mee C, Tyrchan C, O'Donovan M, Sjö P. Shamovsky I, et al. Among authors: mee c. Chem Res Toxicol. 2012 Oct 15;25(10):2236-52. doi: 10.1021/tx300313b. Epub 2012 Sep 20. Chem Res Toxicol. 2012. PMID: 22946514

2

Formaldehyde is a bacterial mutagen in a range of Salmonella and Escherichia indicator strains.

O'Donovan MR, Mee CD. O'Donovan MR, et al. Among authors: mee cd. Mutagenesis. 1993 Nov;8(6):577-81. doi: 10.1093/mutage/8.6.577. Mutagenesis. 1993. PMID: 8133788

3

Explanation for main features of structure-genotoxicity relationships of aromatic amines by theoretical studies of their activation pathways in CYP1A2.

Shamovsky I, Ripa L, Börjesson L, Mee C, Nordén B, Hansen P, Hasselgren C, O'Donovan M, Sjö P. Shamovsky I, et al. Among authors: mee c. J Am Chem Soc. 2011 Oct 12;133(40):16168-85. doi: 10.1021/ja206427u. Epub 2011 Sep 21. J Am Chem Soc. 2011. PMID: 21894985

4

Theoretical studies of the mechanism of N-hydroxylation of primary aromatic amines by cytochrome P450 1A2: radicaloid or anionic?

Ripa L, Mee C, Sjö P, Shamovsky I. Ripa L, et al. Among authors: mee c. Chem Res Toxicol. 2014 Feb 17;27(2):265-78. doi: 10.1021/tx400376u. Epub 2014 Jan 24. Chem Res Toxicol. 2014. PMID: 24410629

5

Experimental testing of quantum mechanical predictions of mutagenicity: aminopyrazoles.

Leach AG, McCoull W, Bailey A, Barton P, Mee C, Rosevere E. Leach AG, et al. Among authors: mee c. Chem Res Toxicol. 2013 May 20;26(5):703-9. doi: 10.1021/tx3005136. Epub 2013 Apr 17. Chem Res Toxicol. 2013. PMID: 23541044

6

Sensitivity of Salmonella typhimurium TA97a to the type of agar used for preparation of Vogel-Bonner plates.

Wilcox P, Wedd DJ, Williams WR, Mee CD, O'Donovan MR. Wilcox P, et al. Among authors: mee cd. Mutagenesis. 1992 Jan;7(1):13-8. doi: 10.1093/mutage/7.1.13. Mutagenesis. 1992. PMID: 1635450

7

Discovery and optimization of a series of carbazole ureas as NPY5 antagonists for the treatment of obesity.

Block MH, Boyer S, Brailsford W, Brittain DR, Carroll D, Chapman S, Clarke DS, Donald CS, Foote KM, Godfrey L, Ladner A, Marsham PR, Masters DJ, Mee CD, O'Donovan MR, Pease JE, Pickup AG, Rayner JW, Roberts A, Schofield P, Suleman A, Turnbull AV. Block MH, et al. J Med Chem. 2002 Aug 1;45(16):3509-23. doi: 10.1021/jm011125x. J Med Chem. 2002. PMID: 12139462

8

Boronic acids-a novel class of bacterial mutagen.

O'Donovan MR, Mee CD, Fenner S, Teasdale A, Phillips DH. O'Donovan MR, et al. Mutat Res. 2011 Sep 18;724(1-2):1-6. doi: 10.1016/j.mrgentox.2011.05.006. Epub 2011 May 26. Mutat Res. 2011. PMID: 21645632

9

Rationally designing safer anilines: the challenging case of 4-aminobiphenyls.

Birch AM, Groombridge S, Law R, Leach AG, Mee CD, Schramm C. Birch AM, et al. Among authors: mee cd. J Med Chem. 2012 Apr 26;55(8):3923-33. doi: 10.1021/jm3001295. Epub 2012 Apr 4. J Med Chem. 2012. PMID: 22475078

10

Escaping the cohort of concern: in vitro experimental evidence supports non-mutagenicity of N-nitroso-hydrochlorothiazide.

Gandhi RD, Hickert S, Hoevelmann Y, Mee CD, Schlingemann J, Adams A, Blanazs A, Simon S, Elloway J, Rigger L, Teasdale A, Beaumont CV, Wright L, Doherty A. Gandhi RD, et al. Among authors: mee cd. Arch Toxicol. 2024 Dec;98(12):4159-4172. doi: 10.1007/s00204-024-03859-3. Epub 2024 Sep 11. Arch Toxicol. 2024. PMID: 39259282 Free PMC article.

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