Dinsdale D - Search Results

1

A novel cellular stress response characterised by a rapid reorganisation of membranes of the endoplasmic reticulum.

Varadarajan S, Bampton ET, Smalley JL, Tanaka K, Caves RE, Butterworth M, Wei J, Pellecchia M, Mitcheson J, Gant TW, Dinsdale D, Cohen GM. Varadarajan S, et al. Among authors: dinsdale d. Cell Death Differ. 2012 Dec;19(12):1896-907. doi: 10.1038/cdd.2012.108. Epub 2012 Sep 7. Cell Death Differ. 2012. PMID: 22955944 Free PMC article.

2

Endoplasmic reticulum membrane reorganization is regulated by ionic homeostasis.

Varadarajan S, Tanaka K, Smalley JL, Bampton ET, Pellecchia M, Dinsdale D, Willars GB, Cohen GM. Varadarajan S, et al. Among authors: dinsdale d. PLoS One. 2013;8(2):e56603. doi: 10.1371/journal.pone.0056603. Epub 2013 Feb 15. PLoS One. 2013. PMID: 23457590 Free PMC article.

3

Sabutoclax (BI97C1) and BI112D1, putative inhibitors of MCL-1, induce mitochondrial fragmentation either upstream of or independent of apoptosis.

Varadarajan S, Butterworth M, Wei J, Pellecchia M, Dinsdale D, Cohen GM. Varadarajan S, et al. Among authors: dinsdale d. Neoplasia. 2013 May;15(5):568-78. doi: 10.1593/neo.13230. Neoplasia. 2013. PMID: 23633928 Free PMC article.

4

A novel paradigm for rapid ABT-737-induced apoptosis involving outer mitochondrial membrane rupture in primary leukemia and lymphoma cells.

Vogler M, Dinsdale D, Sun XM, Young KW, Butterworth M, Nicotera P, Dyer MJ, Cohen GM. Vogler M, et al. Among authors: dinsdale d. Cell Death Differ. 2008 May;15(5):820-30. doi: 10.1038/cdd.2008.25. Epub 2008 Feb 29. Cell Death Differ. 2008. PMID: 18309326

5

Bcl-2 inhibitors: small molecules with a big impact on cancer therapy.

Vogler M, Dinsdale D, Dyer MJ, Cohen GM. Vogler M, et al. Among authors: dinsdale d. Cell Death Differ. 2009 Mar;16(3):360-7. doi: 10.1038/cdd.2008.137. Epub 2008 Sep 19. Cell Death Differ. 2009. PMID: 18806758 Review.

6

Evaluation and critical assessment of putative MCL-1 inhibitors.

Varadarajan S, Vogler M, Butterworth M, Dinsdale D, Walensky LD, Cohen GM. Varadarajan S, et al. Among authors: dinsdale d. Cell Death Differ. 2013 Nov;20(11):1475-84. doi: 10.1038/cdd.2013.79. Epub 2013 Jul 5. Cell Death Differ. 2013. PMID: 23832116 Free PMC article.

7

Role of NOXA and its ubiquitination in proteasome inhibitor-induced apoptosis in chronic lymphocytic leukemia cells.

Baou M, Kohlhaas SL, Butterworth M, Vogler M, Dinsdale D, Walewska R, Majid A, Eldering E, Dyer MJ, Cohen GM. Baou M, et al. Among authors: dinsdale d. Haematologica. 2010 Sep;95(9):1510-8. doi: 10.3324/haematol.2010.022368. Epub 2010 Apr 7. Haematologica. 2010. PMID: 20378569 Free PMC article.

8

BCL2/BCL-X(L) inhibition induces apoptosis, disrupts cellular calcium homeostasis, and prevents platelet activation.

Vogler M, Hamali HA, Sun XM, Bampton ET, Dinsdale D, Snowden RT, Dyer MJ, Goodall AH, Cohen GM. Vogler M, et al. Among authors: dinsdale d. Blood. 2011 Jun 30;117(26):7145-54. doi: 10.1182/blood-2011-03-344812. Epub 2011 May 11. Blood. 2011. PMID: 21562047 Free article.

9

Apoptosis, in human monocytic THP.1 cells, results in the release of cytochrome c from mitochondria prior to their ultracondensation, formation of outer membrane discontinuities and reduction in inner membrane potential.

Zhuang J, Dinsdale D, Cohen GM. Zhuang J, et al. Among authors: dinsdale d. Cell Death Differ. 1998 Nov;5(11):953-62. doi: 10.1038/sj.cdd.4400440. Cell Death Differ. 1998. PMID: 9846182

10

Apoptosis in human monocytic THP.1 cells involves several distinct targets of N-tosyl-L-phenylalanyl chloromethyl ketone (TPCK).

Zhu H, Dinsdale D, Alnemri ES, Cohen GM. Zhu H, et al. Among authors: dinsdale d. Cell Death Differ. 1997 Oct;4(7):590-9. doi: 10.1038/sj.cdd.4400284. Cell Death Differ. 1997. PMID: 14555972

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