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A complex immunodeficiency is based on U1 snRNP-mediated poly(A) site suppression.
Langemeier J, Schrom EM, Rabner A, Radtke M, Zychlinski D, Saborowski A, Bohn G, Mandel-Gutfreund Y, Bodem J, Klein C, Bohne J. Langemeier J, et al. Among authors: saborowski a. EMBO J. 2012 Oct 17;31(20):4035-44. doi: 10.1038/emboj.2012.252. Epub 2012 Sep 11. EMBO J. 2012. PMID: 22968171 Free PMC article.
Generation of focal mutations and large genomic deletions in the pancreas using inducible in vivo genome editing.
Mishra A, Emamgholi F, Erlangga Z, Hartleben B, Unger K, Wolff K, Teichmann U, Kessel M, Woller N, Kühnel F, Dow LE, Manns MP, Vogel A, Lowe SW, Saborowski A, Saborowski M. Mishra A, et al. Among authors: saborowski m, saborowski a. Carcinogenesis. 2020 May 14;41(3):334-344. doi: 10.1093/carcin/bgz108. Carcinogenesis. 2020. PMID: 31170286 Free PMC article.
Cholangiocellular Carcinoma.
Vogel A, Saborowski A. Vogel A, et al. Among authors: saborowski a. Digestion. 2017;95(3):181-185. doi: 10.1159/000454763. Epub 2017 Mar 14. Digestion. 2017. PMID: 28288474 Free article.
Growth differentiation factor 11 attenuates liver fibrosis via expansion of liver progenitor cells.
Dai Z, Song G, Balakrishnan A, Yang T, Yuan Q, Möbus S, Weiss AC, Bentler M, Zhu J, Jiang X, Shen X, Bantel H, Jaeckel E, Kispert A, Vogel A, Saborowski A, Büning H, Manns M, Cantz T, Ott M, Sharma AD. Dai Z, et al. Among authors: saborowski a. Gut. 2020 Jun;69(6):1104-1115. doi: 10.1136/gutjnl-2019-318812. Epub 2019 Nov 25. Gut. 2020. PMID: 31767630 Free PMC article.
Foretinib is a potent inhibitor of oncogenic ROS1 fusion proteins.
Davare MA, Saborowski A, Eide CA, Tognon C, Smith RL, Elferich J, Agarwal A, Tyner JW, Shinde UP, Lowe SW, Druker BJ. Davare MA, et al. Among authors: saborowski a. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19519-24. doi: 10.1073/pnas.1319583110. Epub 2013 Nov 11. Proc Natl Acad Sci U S A. 2013. PMID: 24218589 Free PMC article.
A modular and flexible ESC-based mouse model of pancreatic cancer.
Saborowski M, Saborowski A, Morris JP 4th, Bosbach B, Dow LE, Pelletier J, Klimstra DS, Lowe SW. Saborowski M, et al. Among authors: saborowski a. Genes Dev. 2014 Jan 1;28(1):85-97. doi: 10.1101/gad.232082.113. Genes Dev. 2014. PMID: 24395249 Free PMC article.
Disruption of CRAF-mediated MEK activation is required for effective MEK inhibition in KRAS mutant tumors.
Lito P, Saborowski A, Yue J, Solomon M, Joseph E, Gadal S, Saborowski M, Kastenhuber E, Fellmann C, Ohara K, Morikami K, Miura T, Lukacs C, Ishii N, Lowe S, Rosen N. Lito P, et al. Among authors: saborowski m, saborowski a. Cancer Cell. 2014 May 12;25(5):697-710. doi: 10.1016/j.ccr.2014.03.011. Epub 2014 Apr 17. Cancer Cell. 2014. PMID: 24746704 Free PMC article.
Dual Role of the Adaptive Immune System in Liver Injury and Hepatocellular Carcinoma Development.
Endig J, Buitrago-Molina LE, Marhenke S, Reisinger F, Saborowski A, Schütt J, Limbourg F, Könecke C, Schreder A, Michael A, Misslitz AC, Healy ME, Geffers R, Clavel T, Haller D, Unger K, Finegold M, Weber A, Manns MP, Longerich T, Heikenwälder M, Vogel A. Endig J, et al. Among authors: saborowski a. Cancer Cell. 2016 Aug 8;30(2):308-323. doi: 10.1016/j.ccell.2016.06.009. Epub 2016 Jul 28. Cancer Cell. 2016. PMID: 27478039 Free article.
58 results