Dzamko N - Search Results

1

An emerging role for LRRK2 in the immune system.

Dzamko N, Halliday GM. Dzamko N, et al. Biochem Soc Trans. 2012 Oct;40(5):1134-9. doi: 10.1042/BST20120119. Biochem Soc Trans. 2012. PMID: 22988878 Review.

2

Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease.

Nichols RJ, Dzamko N, Hutti JE, Cantley LC, Deak M, Moran J, Bamborough P, Reith AD, Alessi DR. Nichols RJ, et al. Among authors: dzamko n. Biochem J. 2009 Oct 23;424(1):47-60. doi: 10.1042/BJ20091035. Biochem J. 2009. PMID: 19740074 Free PMC article.

3

14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization.

Nichols RJ, Dzamko N, Morrice NA, Campbell DG, Deak M, Ordureau A, Macartney T, Tong Y, Shen J, Prescott AR, Alessi DR. Nichols RJ, et al. Among authors: dzamko n. Biochem J. 2010 Sep 15;430(3):393-404. doi: 10.1042/BJ20100483. Biochem J. 2010. PMID: 20642453 Free PMC article.

4

Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser(910)/Ser(935), disruption of 14-3-3 binding and altered cytoplasmic localization.

Dzamko N, Deak M, Hentati F, Reith AD, Prescott AR, Alessi DR, Nichols RJ. Dzamko N, et al. Biochem J. 2010 Sep 15;430(3):405-13. doi: 10.1042/BJ20100784. Biochem J. 2010. PMID: 20659021 Free PMC article.

5

The IkappaB kinase family phosphorylates the Parkinson's disease kinase LRRK2 at Ser935 and Ser910 during Toll-like receptor signaling.

Dzamko N, Inesta-Vaquera F, Zhang J, Xie C, Cai H, Arthur S, Tan L, Choi H, Gray N, Cohen P, Pedrioli P, Clark K, Alessi DR. Dzamko N, et al. PLoS One. 2012;7(6):e39132. doi: 10.1371/journal.pone.0039132. Epub 2012 Jun 18. PLoS One. 2012. PMID: 22723946 Free PMC article.

6

Measurement of LRRK2 and Ser910/935 phosphorylated LRRK2 in peripheral blood mononuclear cells from idiopathic Parkinson's disease patients.

Dzamko N, Chua G, Ranola M, Rowe DB, Halliday GM. Dzamko N, et al. J Parkinsons Dis. 2013;3(2):145-52. doi: 10.3233/JPD-130174. J Parkinsons Dis. 2013. PMID: 23938344

7

DNA extraction from fresh-frozen and formalin-fixed, paraffin-embedded human brain tissue.

Wang JH, Gouda-Vossos A, Dzamko N, Halliday G, Huang Y. Wang JH, et al. Among authors: dzamko n. Neurosci Bull. 2013 Oct;29(5):649-54. doi: 10.1007/s12264-013-1379-y. Epub 2013 Aug 30. Neurosci Bull. 2013. PMID: 23996594 Free PMC article.

8

Parkinson's disease-implicated kinases in the brain; insights into disease pathogenesis.

Dzamko N, Zhou J, Huang Y, Halliday GM. Dzamko N, et al. Front Mol Neurosci. 2014 Jun 24;7:57. doi: 10.3389/fnmol.2014.00057. eCollection 2014. Front Mol Neurosci. 2014. PMID: 25009465 Free PMC article. Review.

9

Inflammation is genetically implicated in Parkinson's disease.

Dzamko N, Geczy CL, Halliday GM. Dzamko N, et al. Neuroscience. 2015 Aug 27;302:89-102. doi: 10.1016/j.neuroscience.2014.10.028. Epub 2014 Oct 22. Neuroscience. 2015. PMID: 25450953 Review.

10

Optimisation of LRRK2 inhibitors and assessment of functional efficacy in cell-based models of neuroinflammation.

Munoz L, Kavanagh ME, Phoa AF, Heng B, Dzamko N, Chen EJ, Doddareddy MR, Guillemin GJ, Kassiou M. Munoz L, et al. Among authors: dzamko n. Eur J Med Chem. 2015 May 5;95:29-34. doi: 10.1016/j.ejmech.2015.03.003. Epub 2015 Mar 3. Eur J Med Chem. 2015. PMID: 25791676

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

71 results

Search Page

Filters