Karsdal M - Search Results

1

Matrix metalloproteinase-dependent turnover of cartilage, synovial membrane, and connective tissue is elevated in rats with collagen induced arthritis.

Siebuhr AS, Wang J, Karsdal M, Bay-Jensen AC, Y J, Q Z. Siebuhr AS, et al. Among authors: karsdal m. J Transl Med. 2012 Sep 20;10:195. doi: 10.1186/1479-5876-10-195. J Transl Med. 2012. PMID: 22992383 Free PMC article.

2

Induction of increased cAMP levels in articular chondrocytes blocks matrix metalloproteinase-mediated cartilage degradation, but not aggrecanase-mediated cartilage degradation.

Karsdal MA, Sumer EU, Wulf H, Madsen SH, Christiansen C, Fosang AJ, Sondergaard BC. Karsdal MA, et al. Arthritis Rheum. 2007 May;56(5):1549-58. doi: 10.1002/art.22599. Arthritis Rheum. 2007. PMID: 17469134 Free article.

3

Evaluation of cartilage damage by measuring collagen degradation products in joint extracts in a traumatic model of osteoarthritis.

Nielsen RH, Stoop R, Leeming DJ, Stolina M, Qvist P, Christiansen C, Karsdal MA. Nielsen RH, et al. Among authors: karsdal ma. Biomarkers. 2008 Feb;13(1):79-87. doi: 10.1080/13547500701615108. Biomarkers. 2008. PMID: 17852072

4

Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity.

Karsdal MA, Madsen SH, Christiansen C, Henriksen K, Fosang AJ, Sondergaard BC. Karsdal MA, et al. Arthritis Res Ther. 2008;10(3):R63. doi: 10.1186/ar2434. Epub 2008 May 30. Arthritis Res Ther. 2008. PMID: 18513402 Free PMC article.

5

Biochemical markers of joint tissue turnover.

Bay-Jensen AC, Sondergaard BC, Christiansen C, Karsdal MA, Madsen SH, Qvist P. Bay-Jensen AC, et al. Assay Drug Dev Technol. 2010 Feb;8(1):118-24. doi: 10.1089/adt.2009.0199. Assay Drug Dev Technol. 2010. PMID: 19715454 Review.

6

Aggrecanase- and matrix metalloproteinase-mediated aggrecan degradation is associated with different molecular characteristics of aggrecan and separated in time ex vivo.

Madsen SH, Sumer EU, Bay-Jensen AC, Sondergaard BC, Qvist P, Karsdal MA. Madsen SH, et al. Biomarkers. 2010 May;15(3):266-76. doi: 10.3109/13547500903521810. Biomarkers. 2010. PMID: 20039789

7

Matrix metalloproteinase-9-mediated type III collagen degradation as a novel serological biochemical marker for liver fibrogenesis.

Veidal SS, Vassiliadis E, Barascuk N, Zhang C, Segovia-Silvestre T, Klickstein L, Larsen MR, Qvist P, Christiansen C, Vainer B, Karsdal MA. Veidal SS, et al. Liver Int. 2010 Oct;30(9):1293-304. doi: 10.1111/j.1478-3231.2010.02309.x. Liver Int. 2010. PMID: 20666994

8

Enzyme-linked immunosorbent assay (ELISAs) for metalloproteinase derived type II collagen neoepitope, CIIM--increased serum CIIM in subjects with severe radiographic osteoarthritis.

Bay-Jensen AC, Liu Q, Byrjalsen I, Li Y, Wang J, Pedersen C, Leeming DJ, Dam EB, Zheng Q, Qvist P, Karsdal MA. Bay-Jensen AC, et al. Clin Biochem. 2011 Apr;44(5-6):423-9. doi: 10.1016/j.clinbiochem.2011.01.001. Epub 2011 Jan 9. Clin Biochem. 2011. PMID: 21223960

9

Measurement of matrix metalloproteinase 9-mediated collagen type III degradation fragment as a marker of skin fibrosis.

Vassiliadis E, Veidal SS, Barascuk N, Mullick JB, Clausen RE, Larsen L, Simonsen H, Larsen DV, Bay-Jensen AC, Segovia-Silvestre T, Leeming DJ, Karsdal MA. Vassiliadis E, et al. BMC Dermatol. 2011 Mar 29;11:6. doi: 10.1186/1471-5945-11-6. BMC Dermatol. 2011. PMID: 21447148 Free PMC article.

10

Development and validation of an enzyme-linked immunosorbent assay for the quantification of a specific MMP-9 mediated degradation fragment of type III collagen--A novel biomarker of atherosclerotic plaque remodeling.

Barascuk N, Vassiliadis E, Larsen L, Wang J, Zheng Q, Xing R, Cao Y, Crespo C, Lapret I, Sabatini M, Villeneuve N, Vilaine JP, Rasmussen LM, Register TC, Karsdal MA. Barascuk N, et al. Among authors: karsdal ma. Clin Biochem. 2011 Jul;44(10-11):900-6. doi: 10.1016/j.clinbiochem.2011.04.004. Epub 2011 Apr 30. Clin Biochem. 2011. PMID: 21549691

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