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Genetic ablation of calcium-independent phospholipase A2gamma leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotype.
Mancuso DJ, Sims HF, Han X, Jenkins CM, Guan SP, Yang K, Moon SH, Pietka T, Abumrad NA, Schlesinger PH, Gross RW. Mancuso DJ, et al. J Biol Chem. 2007 Nov 30;282(48):34611-22. doi: 10.1074/jbc.M707795200. Epub 2007 Oct 8. J Biol Chem. 2007. PMID: 17923475 Free PMC article.
Genetic ablation of calcium-independent phospholipase A2gamma prevents obesity and insulin resistance during high fat feeding by mitochondrial uncoupling and increased adipocyte fatty acid oxidation.
Mancuso DJ, Sims HF, Yang K, Kiebish MA, Su X, Jenkins CM, Guan S, Moon SH, Pietka T, Nassir F, Schappe T, Moore K, Han X, Abumrad NA, Gross RW. Mancuso DJ, et al. J Biol Chem. 2010 Nov 19;285(47):36495-510. doi: 10.1074/jbc.M110.115766. Epub 2010 Sep 3. J Biol Chem. 2010. PMID: 20817734 Free PMC article.
Association between specific adipose tissue CD4+ T-cell populations and insulin resistance in obese individuals.
Fabbrini E, Cella M, McCartney SA, Fuchs A, Abumrad NA, Pietka TA, Chen Z, Finck BN, Han DH, Magkos F, Conte C, Bradley D, Fraterrigo G, Eagon JC, Patterson BW, Colonna M, Klein S. Fabbrini E, et al. Among authors: pietka ta. Gastroenterology. 2013 Aug;145(2):366-74.e1-3. doi: 10.1053/j.gastro.2013.04.010. Epub 2013 Apr 15. Gastroenterology. 2013. PMID: 23597726 Free PMC article.
Sulfo-N-succinimidyl oleate (SSO) inhibits fatty acid uptake and signaling for intracellular calcium via binding CD36 lysine 164: SSO also inhibits oxidized low density lipoprotein uptake by macrophages.
Kuda O, Pietka TA, Demianova Z, Kudova E, Cvacka J, Kopecky J, Abumrad NA. Kuda O, et al. Among authors: pietka ta. J Biol Chem. 2013 May 31;288(22):15547-55. doi: 10.1074/jbc.M113.473298. Epub 2013 Apr 18. J Biol Chem. 2013. PMID: 23603908 Free PMC article.
52 results