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Structural variation in two human genomes mapped at single-nucleotide resolution by whole genome de novo assembly.
Li Y, Zheng H, Luo R, Wu H, Zhu H, Li R, Cao H, Wu B, Huang S, Shao H, Ma H, Zhang F, Feng S, Zhang W, Du H, Tian G, Li J, Zhang X, Li S, Bolund L, Kristiansen K, de Smith AJ, Blakemore AI, Coin LJ, Yang H, Wang J, Wang J. Li Y, et al. Among authors: cao h. Nat Biotechnol. 2011 Jul 24;29(8):723-30. doi: 10.1038/nbt.1904. Nat Biotechnol. 2011. PMID: 21785424
De novo assembly of a haplotype-resolved human genome.
Cao H, Wu H, Luo R, Huang S, Sun Y, Tong X, Xie Y, Liu B, Yang H, Zheng H, Li J, Li B, Wang Y, Yang F, Sun P, Liu S, Gao P, Huang H, Sun J, Chen D, He G, Huang W, Huang Z, Li Y, Tellier LC, Liu X, Feng Q, Xu X, Zhang X, Bolund L, Krogh A, Kristiansen K, Drmanac R, Drmanac S, Nielsen R, Li S, Wang J, Yang H, Li Y, Wong GK, Wang J. Cao H, et al. Nat Biotechnol. 2015 Jun;33(6):617-22. doi: 10.1038/nbt.3200. Epub 2015 May 25. Nat Biotechnol. 2015. PMID: 26006006
Building the sequence map of the human pan-genome.
Li R, Li Y, Zheng H, Luo R, Zhu H, Li Q, Qian W, Ren Y, Tian G, Li J, Zhou G, Zhu X, Wu H, Qin J, Jin X, Li D, Cao H, Hu X, Blanche H, Cann H, Zhang X, Li S, Bolund L, Kristiansen K, Yang H, Wang J, Wang J. Li R, et al. Among authors: cao h. Nat Biotechnol. 2010 Jan;28(1):57-63. doi: 10.1038/nbt.1596. Epub 2009 Dec 7. Nat Biotechnol. 2010. PMID: 19997067
Sequencing of 50 human exomes reveals adaptation to high altitude.
Yi X, Liang Y, Huerta-Sanchez E, Jin X, Cuo ZX, Pool JE, Xu X, Jiang H, Vinckenbosch N, Korneliussen TS, Zheng H, Liu T, He W, Li K, Luo R, Nie X, Wu H, Zhao M, Cao H, Zou J, Shan Y, Li S, Yang Q, Asan, Ni P, Tian G, Xu J, Liu X, Jiang T, Wu R, Zhou G, Tang M, Qin J, Wang T, Feng S, Li G, Huasang, Luosang J, Wang W, Chen F, Wang Y, Zheng X, Li Z, Bianba Z, Yang G, Wang X, Tang S, Gao G, Chen Y, Luo Z, Gusang L, Cao Z, Zhang Q, Ouyang W, Ren X, Liang H, Zheng H, Huang Y, Li J, Bolund L, Kristiansen K, Li Y, Zhang Y, Zhang X, Li R, Li S, Yang H, Nielsen R, Wang J, Wang J. Yi X, et al. Among authors: cao h, cao z. Science. 2010 Jul 2;329(5987):75-8. doi: 10.1126/science.1190371. Science. 2010. PMID: 20595611 Free PMC article.
The DNA methylome of human peripheral blood mononuclear cells.
Li Y, Zhu J, Tian G, Li N, Li Q, Ye M, Zheng H, Yu J, Wu H, Sun J, Zhang H, Chen Q, Luo R, Chen M, He Y, Jin X, Zhang Q, Yu C, Zhou G, Sun J, Huang Y, Zheng H, Cao H, Zhou X, Guo S, Hu X, Li X, Kristiansen K, Bolund L, Xu J, Wang W, Yang H, Wang J, Li R, Beck S, Wang J, Zhang X. Li Y, et al. Among authors: cao h. PLoS Biol. 2010 Nov 9;8(11):e1000533. doi: 10.1371/journal.pbio.1000533. PLoS Biol. 2010. PMID: 21085693 Free PMC article.
A short-read multiplex sequencing method for reliable, cost-effective and high-throughput genotyping in large-scale studies.
Cao H, Wang Y, Zhang W, Chai X, Zhang X, Chen S, Yang F, Zhang C, Guo Y, Liu Y, Tang Z, Chen C, Xue Y, Zhen H, Xu Y, Rao B, Liu T, Zhao M, Zhang W, Li Y, Zhang X, Tellier LC, Krogh A, Kristiansen K, Wang J, Li J. Cao H, et al. Hum Mutat. 2013 Dec;34(12):1715-20. doi: 10.1002/humu.22439. Epub 2013 Oct 7. Hum Mutat. 2013. PMID: 24014314
Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants.
Li Y, Vinckenbosch N, Tian G, Huerta-Sanchez E, Jiang T, Jiang H, Albrechtsen A, Andersen G, Cao H, Korneliussen T, Grarup N, Guo Y, Hellman I, Jin X, Li Q, Liu J, Liu X, Sparsø T, Tang M, Wu H, Wu R, Yu C, Zheng H, Astrup A, Bolund L, Holmkvist J, Jørgensen T, Kristiansen K, Schmitz O, Schwartz TW, Zhang X, Li R, Yang H, Wang J, Hansen T, Pedersen O, Nielsen R, Wang J. Li Y, et al. Among authors: cao h. Nat Genet. 2010 Nov;42(11):969-72. doi: 10.1038/ng.680. Epub 2010 Oct 3. Nat Genet. 2010. PMID: 20890277
An integrated tool to study MHC region: accurate SNV detection and HLA genes typing in human MHC region using targeted high-throughput sequencing.
Cao H, Wu J, Wang Y, Jiang H, Zhang T, Liu X, Xu Y, Liang D, Gao P, Sun Y, Gifford B, D'Ascenzo M, Liu X, Tellier LC, Yang F, Tong X, Chen D, Zheng J, Li W, Richmond T, Xu X, Wang J, Li Y. Cao H, et al. PLoS One. 2013 Jul 24;8(7):e69388. doi: 10.1371/journal.pone.0069388. Print 2013. PLoS One. 2013. PMID: 23894464 Free PMC article.
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