Wang C - Search Results

1

Bmi1 is required for hepatic progenitor cell expansion and liver tumor development.

Fan L, Xu C, Wang C, Tao J, Ho C, Jiang L, Gui B, Huang S, Evert M, Calvisi DF, Chen X. Fan L, et al. Among authors: wang c. PLoS One. 2012;7(9):e46472. doi: 10.1371/journal.pone.0046472. Epub 2012 Sep 28. PLoS One. 2012. PMID: 23029524 Free PMC article.

2

AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/SKP2, and c-Myc pathways.

Ho C, Wang C, Mattu S, Destefanis G, Ladu S, Delogu S, Armbruster J, Fan L, Lee SA, Jiang L, Dombrowski F, Evert M, Chen X, Calvisi DF. Ho C, et al. Among authors: wang c. Hepatology. 2012 Mar;55(3):833-45. doi: 10.1002/hep.24736. Epub 2011 Dec 19. Hepatology. 2012. PMID: 21993994 Free PMC article.

3

Inactivation of Spry2 accelerates AKT-driven hepatocarcinogenesis via activation of MAPK and PKM2 pathways.

Wang C, Delogu S, Ho C, Lee SA, Gui B, Jiang L, Ladu S, Cigliano A, Dombrowski F, Evert M, Calvisi DF, Chen X. Wang C, et al. J Hepatol. 2012 Sep;57(3):577-83. doi: 10.1016/j.jhep.2012.04.026. Epub 2012 May 19. J Hepatol. 2012. PMID: 22617155 Free PMC article.

4

Functional crosstalk between AKT/mTOR and Ras/MAPK pathways in hepatocarcinogenesis: implications for the treatment of human liver cancer.

Wang C, Cigliano A, Delogu S, Armbruster J, Dombrowski F, Evert M, Chen X, Calvisi DF. Wang C, et al. Cell Cycle. 2013 Jul 1;12(13):1999-2010. doi: 10.4161/cc.25099. Epub 2013 Jun 6. Cell Cycle. 2013. PMID: 23759595 Free PMC article.

5

SCD1 Expression is dispensable for hepatocarcinogenesis induced by AKT and Ras oncogenes in mice.

Li L, Wang C, Calvisi DF, Evert M, Pilo MG, Jiang L, Yuneva M, Chen X. Li L, et al. Among authors: wang c. PLoS One. 2013 Sep 19;8(9):e75104. doi: 10.1371/journal.pone.0075104. eCollection 2013. PLoS One. 2013. PMID: 24069385 Free PMC article.

6

4EBP1/eIF4E and p70S6K/RPS6 axes play critical and distinct roles in hepatocarcinogenesis driven by AKT and N-Ras proto-oncogenes in mice.

Wang C, Cigliano A, Jiang L, Li X, Fan B, Pilo MG, Liu Y, Gui B, Sini M, Smith JW, Dombrowski F, Calvisi DF, Evert M, Chen X. Wang C, et al. Hepatology. 2015 Jan;61(1):200-13. doi: 10.1002/hep.27396. Epub 2014 Nov 25. Hepatology. 2015. PMID: 25145583 Free PMC article.

7

SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice.

Delogu S, Wang C, Cigliano A, Utpatel K, Sini M, Longerich T, Waldburger N, Breuhahn K, Jiang L, Ribback S, Dombrowski F, Evert M, Chen X, Calvisi DF. Delogu S, et al. Among authors: wang c. Oncotarget. 2015 Feb 10;6(4):2222-34. doi: 10.18632/oncotarget.2945. Oncotarget. 2015. PMID: 25537506 Free PMC article.

8

Co-activation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liver.

Li X, Tao J, Cigliano A, Sini M, Calderaro J, Azoulay D, Wang C, Liu Y, Jiang L, Evert K, Demartis MI, Ribback S, Utpatel K, Dombrowski F, Evert M, Calvisi DF, Chen X. Li X, et al. Among authors: wang c. Oncotarget. 2015 Apr 30;6(12):10102-15. doi: 10.18632/oncotarget.3546. Oncotarget. 2015. PMID: 25826091 Free PMC article.

9

Activated mutant forms of PIK3CA cooperate with RasV12 or c-Met to induce liver tumour formation in mice via AKT2/mTORC1 cascade.

Wang C, Che L, Hu J, Zhang S, Jiang L, Latte G, Demartis MI, Tao J, Gui B, Pilo MG, Ribback S, Dombrowski F, Evert M, Calvisi DF, Chen X. Wang C, et al. Liver Int. 2016 Aug;36(8):1176-86. doi: 10.1111/liv.13055. Epub 2016 Jan 30. Liver Int. 2016. PMID: 26716908 Free PMC article.

10

Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans.

Li L, Pilo GM, Li X, Cigliano A, Latte G, Che L, Joseph C, Mela M, Wang C, Jiang L, Ribback S, Simile MM, Pascale RM, Dombrowski F, Evert M, Semenkovich CF, Chen X, Calvisi DF. Li L, et al. Among authors: wang c. J Hepatol. 2016 Feb;64(2):333-341. doi: 10.1016/j.jhep.2015.10.004. Epub 2015 Oct 22. J Hepatol. 2016. PMID: 26476289 Free PMC article.

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