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Page 1
Death receptor pathway activation and increase of ROS production by the triple epigenetic inhibitor UVI5008.
Nebbioso A, Pereira R, Khanwalkar H, Matarese F, García-Rodríguez J, Miceli M, Logie C, Kedinger V, Ferrara F, Stunnenberg HG, de Lera AR, Gronemeyer H, Altucci L. Nebbioso A, et al. Among authors: stunnenberg hg. Mol Cancer Ther. 2011 Dec;10(12):2394-404. doi: 10.1158/1535-7163.MCT-11-0525. Epub 2011 Oct 6. Mol Cancer Ther. 2011. PMID: 21980132
Context-selective death of acute myeloid leukemia cells triggered by the novel hybrid retinoid-HDAC inhibitor MC2392.
De Bellis F, Carafa V, Conte M, Rotili D, Petraglia F, Matarese F, Françoijs KJ, Ablain J, Valente S, Castellano R, Goubard A, Collette Y, Mandoli A, Martens JH, de Thé H, Nebbioso A, Mai A, Stunnenberg HG, Altucci L. De Bellis F, et al. Among authors: stunnenberg hg. Cancer Res. 2014 Apr 15;74(8):2328-39. doi: 10.1158/0008-5472.CAN-13-2568. Epub 2014 Feb 24. Cancer Res. 2014. PMID: 24566867
c-Myc Modulation and Acetylation Is a Key HDAC Inhibitor Target in Cancer.
Nebbioso A, Carafa V, Conte M, Tambaro FP, Abbondanza C, Martens J, Nees M, Benedetti R, Pallavicini I, Minucci S, Garcia-Manero G, Iovino F, Lania G, Ingenito C, Belsito Petrizzi V, Stunnenberg HG, Altucci L. Nebbioso A, et al. Among authors: stunnenberg hg. Clin Cancer Res. 2017 May 15;23(10):2542-2555. doi: 10.1158/1078-0432.CCR-15-2388. Epub 2016 Jun 29. Clin Cancer Res. 2017. PMID: 27358484
Time for epigenetics.
Altucci L, Stunnenberg HG. Altucci L, et al. Among authors: stunnenberg hg. Int J Biochem Cell Biol. 2009 Jan;41(1):2-3. doi: 10.1016/j.biocel.2008.09.010. Epub 2008 Sep 21. Int J Biochem Cell Biol. 2009. PMID: 18852065 No abstract available.
CBX2 shapes chromatin accessibility promoting AML via p38 MAPK signaling pathway.
Del Gaudio N, Di Costanzo A, Liu NQ, Conte L, Dell'Aversana C, Bove G, Benedetti R, Montella L, Ciardiello F, Carafa V, Ambrosino C, Tucci V, Conte M, Martens JHA, Stunnenberg HG, Nebbioso A, Altucci L. Del Gaudio N, et al. Among authors: stunnenberg hg. Mol Cancer. 2022 Jun 9;21(1):125. doi: 10.1186/s12943-022-01603-y. Mol Cancer. 2022. PMID: 35681235 Free PMC article.
Combined HAT/EZH2 modulation leads to cancer-selective cell death.
Petraglia F, Singh AA, Carafa V, Nebbioso A, Conte M, Scisciola L, Valente S, Baldi A, Mandoli A, Petrizzi VB, Ingenito C, De Falco S, Cicatiello V, Apicella I, Janssen-Megens EM, Kim B, Yi G, Logie C, Heath S, Ruvo M, Wierenga ATJ, Flicek P, Yaspo ML, Della Valle V, Bernard O, Tomassi S, Novellino E, Feoli A, Sbardella G, Gut I, Vellenga E, Stunnenberg HG, Mai A, Martens JHA, Altucci L. Petraglia F, et al. Among authors: stunnenberg hg. Oncotarget. 2018 May 22;9(39):25630-25646. doi: 10.18632/oncotarget.25428. eCollection 2018 May 22. Oncotarget. 2018. PMID: 29876013 Free PMC article.
390 results