Deng L - Search Results

1

Thermodynamic Investigation of Inhibitor Binding to 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase.

Cai G, Deng L, Fryszczyn BG, Brown NG, Liu Z, Jiang H, Palzkill T, Song Y. Cai G, et al. Among authors: deng l. ACS Med Chem Lett. 2012 Jun 14;3(6):496-500. doi: 10.1021/ml300071w. Epub 2012 May 7. ACS Med Chem Lett. 2012. PMID: 23050057 Free PMC article.

2

Coordination chemistry based approach to lipophilic inhibitors of 1-deoxy-D-xylulose-5-phosphate reductoisomerase.

Deng L, Sundriyal S, Rubio V, Shi ZZ, Song Y. Deng L, et al. J Med Chem. 2009 Nov 12;52(21):6539-42. doi: 10.1021/jm9012592. J Med Chem. 2009. PMID: 19888756

3

Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate Complexes.

Deng L, Endo K, Kato M, Cheng G, Yajima S, Song Y. Deng L, et al. ACS Med Chem Lett. 2011 Feb 10;2(2):165-170. doi: 10.1021/ml100243r. ACS Med Chem Lett. 2011. PMID: 21379374 Free PMC article.

4

Inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase by lipophilic phosphonates: SAR, QSAR, and crystallographic studies.

Deng L, Diao J, Chen P, Pujari V, Yao Y, Cheng G, Crick DC, Prasad BV, Song Y. Deng L, et al. J Med Chem. 2011 Jul 14;54(13):4721-34. doi: 10.1021/jm200363d. Epub 2011 Jun 2. J Med Chem. 2011. PMID: 21561155 Free PMC article.

5

Selective inhibitors of histone methyltransferase DOT1L: design, synthesis, and crystallographic studies.

Yao Y, Chen P, Diao J, Cheng G, Deng L, Anglin JL, Prasad BV, Song Y. Yao Y, et al. Among authors: deng l. J Am Chem Soc. 2011 Oct 26;133(42):16746-9. doi: 10.1021/ja206312b. Epub 2011 Oct 4. J Am Chem Soc. 2011. PMID: 21936531 Free PMC article.

6

2-Substituted 4,5-dihydrothiazole-4-carboxylic acids are novel inhibitors of metallo-β-lactamases.

Chen P, Horton LB, Mikulski RL, Deng L, Sundriyal S, Palzkill T, Song Y. Chen P, et al. Among authors: deng l. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6229-32. doi: 10.1016/j.bmcl.2012.08.012. Epub 2012 Aug 10. Bioorg Med Chem Lett. 2012. PMID: 22921080 Free PMC article.

7

Synthesis and structure-activity relationship investigation of adenosine-containing inhibitors of histone methyltransferase DOT1L.

Anglin JL, Deng L, Yao Y, Cai G, Liu Z, Jiang H, Cheng G, Chen P, Dong S, Song Y. Anglin JL, et al. Among authors: deng l. J Med Chem. 2012 Sep 27;55(18):8066-74. doi: 10.1021/jm300917h. Epub 2012 Sep 6. J Med Chem. 2012. PMID: 22924785 Free PMC article.

8

Structural basis of substrate specificity and protease inhibition in Norwalk virus.

Muhaxhiri Z, Deng L, Shanker S, Sankaran B, Estes MK, Palzkill T, Song Y, Prasad BV. Muhaxhiri Z, et al. Among authors: deng l. J Virol. 2013 Apr;87(8):4281-92. doi: 10.1128/JVI.02869-12. Epub 2013 Jan 30. J Virol. 2013. PMID: 23365454 Free PMC article.

9

Expression, characterization and inhibition of Toxoplasma gondii 1-deoxy-D-xylulose-5-phosphate reductoisomerase.

Cai G, Deng L, Xue J, Moreno SN, Striepen B, Song Y. Cai G, et al. Among authors: deng l. Bioorg Med Chem Lett. 2013 Apr 1;23(7):2158-61. doi: 10.1016/j.bmcl.2013.01.097. Epub 2013 Jan 30. Bioorg Med Chem Lett. 2013. PMID: 23428849 Free PMC article.

10

Antimalarial and Structural Studies of Pyridine-containing Inhibitors of 1-Deoxyxylulose-5-phosphate Reductoisomerase.

Xue J, Diao J, Cai G, Deng L, Zheng B, Yao Y, Song Y. Xue J, et al. Among authors: deng l. ACS Med Chem Lett. 2013 Feb 14;4(2):278-282. doi: 10.1021/ml300419r. ACS Med Chem Lett. 2013. PMID: 23795240 Free PMC article.

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