Santos G - Search Results

1

PGC-1α improves glucose homeostasis in skeletal muscle in an activity-dependent manner.

Summermatter S, Shui G, Maag D, Santos G, Wenk MR, Handschin C. Summermatter S, et al. Among authors: santos g. Diabetes. 2013 Jan;62(1):85-95. doi: 10.2337/db12-0291. Epub 2012 Oct 18. Diabetes. 2013. PMID: 23086035 Free PMC article.

2

Peroxisome proliferator-activated receptor {gamma} coactivator 1{alpha} (PGC-1{alpha}) promotes skeletal muscle lipid refueling in vivo by activating de novo lipogenesis and the pentose phosphate pathway.

Summermatter S, Baum O, Santos G, Hoppeler H, Handschin C. Summermatter S, et al. Among authors: santos g. J Biol Chem. 2010 Oct 22;285(43):32793-32800. doi: 10.1074/jbc.M110.145995. Epub 2010 Aug 17. J Biol Chem. 2010. PMID: 20716531 Free PMC article.

3

Coordinated balancing of muscle oxidative metabolism through PGC-1α increases metabolic flexibility and preserves insulin sensitivity.

Summermatter S, Troxler H, Santos G, Handschin C. Summermatter S, et al. Among authors: santos g. Biochem Biophys Res Commun. 2011 Apr 29;408(1):180-5. doi: 10.1016/j.bbrc.2011.04.012. Epub 2011 Apr 8. Biochem Biophys Res Commun. 2011. PMID: 21501593 Free article.

4

Remodeling of calcium handling in skeletal muscle through PGC-1α: impact on force, fatigability, and fiber type.

Summermatter S, Thurnheer R, Santos G, Mosca B, Baum O, Treves S, Hoppeler H, Zorzato F, Handschin C. Summermatter S, et al. Among authors: santos g. Am J Physiol Cell Physiol. 2012 Jan 1;302(1):C88-99. doi: 10.1152/ajpcell.00190.2011. Epub 2011 Sep 14. Am J Physiol Cell Physiol. 2012. PMID: 21918181 Free article.

5

Skeletal muscle PGC-1α controls whole-body lactate homeostasis through estrogen-related receptor α-dependent activation of LDH B and repression of LDH A.

Summermatter S, Santos G, Pérez-Schindler J, Handschin C. Summermatter S, et al. Among authors: santos g. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8738-43. doi: 10.1073/pnas.1212976110. Epub 2013 May 6. Proc Natl Acad Sci U S A. 2013. PMID: 23650363 Free PMC article.

6

The transcriptional coactivator PGC-1α is dispensable for chronic overload-induced skeletal muscle hypertrophy and metabolic remodeling.

Pérez-Schindler J, Summermatter S, Santos G, Zorzato F, Handschin C. Pérez-Schindler J, et al. Among authors: santos g. Proc Natl Acad Sci U S A. 2013 Dec 10;110(50):20314-9. doi: 10.1073/pnas.1312039110. Epub 2013 Nov 25. Proc Natl Acad Sci U S A. 2013. PMID: 24277823 Free PMC article.

7

The coactivator PGC-1α regulates skeletal muscle oxidative metabolism independently of the nuclear receptor PPARβ/δ in sedentary mice fed a regular chow diet.

Pérez-Schindler J, Svensson K, Vargas-Fernández E, Santos G, Wahli W, Handschin C. Pérez-Schindler J, et al. Among authors: santos g. Diabetologia. 2014 Nov;57(11):2405-12. doi: 10.1007/s00125-014-3352-3. Epub 2014 Aug 13. Diabetologia. 2014. PMID: 25116175 Free PMC article.

8

PGC-1α expression in murine AgRP neurons regulates food intake and energy balance.

Gill JF, Delezie J, Santos G, Handschin C. Gill JF, et al. Among authors: santos g. Mol Metab. 2016 May 18;5(7):580-588. doi: 10.1016/j.molmet.2016.05.008. eCollection 2016 Jul. Mol Metab. 2016. PMID: 27408781 Free PMC article.

9

PGC-1α affects aging-related changes in muscle and motor function by modulating specific exercise-mediated changes in old mice.

Gill JF, Santos G, Schnyder S, Handschin C. Gill JF, et al. Among authors: santos g. Aging Cell. 2018 Feb;17(1):e12697. doi: 10.1111/acel.12697. Epub 2017 Oct 25. Aging Cell. 2018. PMID: 29067788 Free PMC article.

10

Peroxisome proliferator-activated receptor γ coactivator 1α regulates mitochondrial calcium homeostasis, sarcoplasmic reticulum stress, and cell death to mitigate skeletal muscle aging.

Gill JF, Delezie J, Santos G, McGuirk S, Schnyder S, Frank S, Rausch M, St-Pierre J, Handschin C. Gill JF, et al. Among authors: santos g. Aging Cell. 2019 Oct;18(5):e12993. doi: 10.1111/acel.12993. Epub 2019 Jul 10. Aging Cell. 2019. PMID: 31290266 Free PMC article.

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