McGovern DP - Search Results

1

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN, Andersen V, Andrews JM, Baidoo L, Balschun T, Bampton PA, Bitton A, Boucher G, Brand S, Büning C, Cohain A, Cichon S, D'Amato M, De Jong D, Devaney KL, Dubinsky M, Edwards C, Ellinghaus D, Ferguson LR, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas J, Haritunians T, Hart A, Hawkey C, Hedl M, Hu X, Karlsen TH, Kupcinskas L, Kugathasan S, Latiano A, Laukens D, Lawrance IC, Lees CW, Louis E, Mahy G, Mansfield J, Morgan AR, Mowat C, Newman W, Palmieri O, Ponsioen CY, Potocnik U, Prescott NJ, Regueiro M, Rotter JI, Russell RK, Sanderson JD, Sans M, Satsangi J, Schreiber S, Simms LA, Sventoraityte J, Targan SR, Taylor KD, Tremelling M, Verspaget HW, De Vos M, Wijmenga C, Wilson DC, Winkelmann J, Xavier RJ, Zeissig S, Zhang B, Zhang CK, Zhao H; International IBD Genetics Consortium (IIBDGC); Silverberg MS, Annese V, Hakonarson H, Brant SR, Radford-Smith G, Mathew CG, Rioux JD, Schadt EE, Daly MJ, Franke A… See abstract for full author list ➔ Jostins L, et al. Among authors: mcgovern dp. Nature. 2012 Nov 1;491(7422):119-24. doi: 10.1038/nature11582. Nature. 2012. PMID: 23128233 Free PMC article.

2

Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF(-kappa)B transcription factors.

van Heel DA, Udalova IA, De Silva AP, McGovern DP, Kinouchi Y, Hull J, Lench NJ, Cardon LR, Carey AH, Jewell DP, Kwiatkowski D. van Heel DA, et al. Among authors: mcgovern dp. Hum Mol Genet. 2002 May 15;11(11):1281-9. doi: 10.1093/hmg/11.11.1281. Hum Mol Genet. 2002. PMID: 12019209

3

Role of NOD2 variants in spondylarthritis.

Crane AM, Bradbury L, van Heel DA, McGovern DP, Brophy S, Rubin L, Siminovitch KA, Wordsworth BP, Calin A, Brown MA. Crane AM, et al. Among authors: mcgovern dp. Arthritis Rheum. 2002 Jun;46(6):1629-33. doi: 10.1002/art.10329. Arthritis Rheum. 2002. PMID: 12115195 Free article.

4

Fine mapping of the IBD1 locus did not identify Crohn disease-associated NOD2 variants: implications for complex disease genetics.

van Heel DA, McGovern DP, Cardon LR, Dechairo BM, Lench NJ, Carey AH, Jewell DP. van Heel DA, et al. Among authors: mcgovern dp. Am J Med Genet. 2002 Aug 15;111(3):253-9. doi: 10.1002/ajmg.10588. Am J Med Genet. 2002. PMID: 12210321

5

Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease.

Negoro K, McGovern DP, Kinouchi Y, Takahashi S, Lench NJ, Shimosegawa T, Carey A, Cardon LR, Jewell DP, van Heel DA. Negoro K, et al. Among authors: mcgovern dp. Gut. 2003 Apr;52(4):541-6. doi: 10.1136/gut.52.4.541. Gut. 2003. PMID: 12631666 Free PMC article.

6

The IBD6 Crohn's disease locus demonstrates complex interactions with CARD15 and IBD5 disease-associated variants.

van Heel DA, Dechairo BM, Dawson G, McGovern DP, Negoro K, Carey AH, Cardon LR, Mackay I, Jewell DP, Lench NJ. van Heel DA, et al. Among authors: mcgovern dp. Hum Mol Genet. 2003 Oct 15;12(20):2569-75. doi: 10.1093/hmg/ddg281. Epub 2003 Aug 19. Hum Mol Genet. 2003. PMID: 12928481

7

Further evidence of IBD5/CARD15 (NOD2) epistasis in the susceptibility to ulcerative colitis.

McGovern DP, Van Heel DA, Negoro K, Ahmad T, Jewell DP. McGovern DP, et al. Am J Hum Genet. 2003 Dec;73(6):1465-6. doi: 10.1086/379745. Am J Hum Genet. 2003. PMID: 14655097 Free PMC article. No abstract available.

8

A common CTLA4 haplotype associated with coeliac disease.

Hunt KA, McGovern DP, Kumar PJ, Ghosh S, Travis SP, Walters JR, Jewell DP, Playford RJ, van Heel DA. Hunt KA, et al. Among authors: mcgovern dp. Eur J Hum Genet. 2005 Apr;13(4):440-4. doi: 10.1038/sj.ejhg.5201357. Eur J Hum Genet. 2005. PMID: 15657618

9

Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease.

McGovern DP, Hysi P, Ahmad T, van Heel DA, Moffatt MF, Carey A, Cookson WO, Jewell DP. McGovern DP, et al. Hum Mol Genet. 2005 May 15;14(10):1245-50. doi: 10.1093/hmg/ddi135. Epub 2005 Mar 24. Hum Mol Genet. 2005. PMID: 15790594

10

Muramyl dipeptide and toll-like receptor sensitivity in NOD2-associated Crohn's disease.

van Heel DA, Ghosh S, Butler M, Hunt KA, Lundberg AM, Ahmad T, McGovern DP, Onnie C, Negoro K, Goldthorpe S, Foxwell BM, Mathew CG, Forbes A, Jewell DP, Playford RJ. van Heel DA, et al. Among authors: mcgovern dp. Lancet. 2005 May 21-27;365(9473):1794-6. doi: 10.1016/S0140-6736(05)66582-8. Lancet. 2005. PMID: 15910952

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