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Darunavir is predominantly unbound to protein in cerebrospinal fluid and concentrations exceed the wild-type HIV-1 median 90% inhibitory concentration.
Croteau D, Rossi SS, Best BM, Capparelli E, Ellis RJ, Clifford DB, Collier AC, Gelman BB, Marra CM, McArthur J, McCutchan JA, Morgello S, Simpson DM, Grant I, Letendre S; CHARTER Group. Croteau D, et al. Among authors: capparelli e. J Antimicrob Chemother. 2013 Mar;68(3):684-9. doi: 10.1093/jac/dks441. Epub 2012 Nov 9. J Antimicrob Chemother. 2013. PMID: 23143899 Free PMC article.
Population pharmacokinetics of abacavir in plasma and cerebrospinal fluid.
Capparelli EV, Letendre SL, Ellis RJ, Patel P, Holland D, McCutchan JA. Capparelli EV, et al. Antimicrob Agents Chemother. 2005 Jun;49(6):2504-6. doi: 10.1128/AAC.49.6.2504-2506.2005. Antimicrob Agents Chemother. 2005. PMID: 15917556 Free PMC article. Clinical Trial.
Population pharmacokinetics of cefepime in the neonate.
Capparelli E, Hochwald C, Rasmussen M, Parham A, Bradley J, Moya F. Capparelli E, et al. Antimicrob Agents Chemother. 2005 Jul;49(7):2760-6. doi: 10.1128/AAC.49.7.2760-2766.2005. Antimicrob Agents Chemother. 2005. PMID: 15980347 Free PMC article.
Multicenter study to determine antibody concentrations and assess the safety of administration of INH-A21, a donor-selected human Staphylococcal immune globulin, in low-birth-weight infants.
Capparelli EV, Bloom BT, Kueser TJ, Oelberg DG, Bifano EM, White RD, Schelonka RL, Pearlman SA, Patti J, Hetherington SV. Capparelli EV, et al. Antimicrob Agents Chemother. 2005 Oct;49(10):4121-7. doi: 10.1128/AAC.49.10.4121-4127.2005. Antimicrob Agents Chemother. 2005. PMID: 16189088 Free PMC article.
Impact of pregnancy on abacavir pharmacokinetics.
Best BM, Mirochnick M, Capparelli EV, Stek A, Burchett SK, Holland DT, Read JS, Smith E, Hu C, Spector SA, Connor JD; PACTG P1026s Study Team. Best BM, et al. Among authors: capparelli ev. AIDS. 2006 Feb 28;20(4):553-60. doi: 10.1097/01.aids.0000210609.52836.d1. AIDS. 2006. PMID: 16470119
454 results