Stiff T - Search Results

1

Identification of the first ATRIP-deficient patient and novel mutations in ATR define a clinical spectrum for ATR-ATRIP Seckel Syndrome.

Ogi T, Walker S, Stiff T, Hobson E, Limsirichaikul S, Carpenter G, Prescott K, Suri M, Byrd PJ, Matsuse M, Mitsutake N, Nakazawa Y, Vasudevan P, Barrow M, Stewart GS, Taylor AM, O'Driscoll M, Jeggo PA. Ogi T, et al. Among authors: stiff t. PLoS Genet. 2012;8(11):e1002945. doi: 10.1371/journal.pgen.1002945. Epub 2012 Nov 8. PLoS Genet. 2012. PMID: 23144622 Free PMC article.

2

Cellular and biochemical impact of a mutation in DNA ligase IV conferring clinical radiosensitivity.

Riballo E, Doherty AJ, Dai Y, Stiff T, Oettinger MA, Jeggo PA, Kysela B. Riballo E, et al. Among authors: stiff t. J Biol Chem. 2001 Aug 17;276(33):31124-32. doi: 10.1074/jbc.M103866200. Epub 2001 May 10. J Biol Chem. 2001. PMID: 11349135 Free article.

3

Ku stimulation of DNA ligase IV-dependent ligation requires inward movement along the DNA molecule.

Kysela B, Doherty AJ, Chovanec M, Stiff T, Ameer-Beg SM, Vojnovic B, Girard PM, Jeggo PA. Kysela B, et al. Among authors: stiff t. J Biol Chem. 2003 Jun 20;278(25):22466-74. doi: 10.1074/jbc.M303273200. Epub 2003 Apr 7. J Biol Chem. 2003. PMID: 12682039 Free article.

4

ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation.

Stiff T, O'Driscoll M, Rief N, Iwabuchi K, Löbrich M, Jeggo PA. Stiff T, et al. Cancer Res. 2004 Apr 1;64(7):2390-6. doi: 10.1158/0008-5472.can-03-3207. Cancer Res. 2004. PMID: 15059890

5

AHNAK interacts with the DNA ligase IV-XRCC4 complex and stimulates DNA ligase IV-mediated double-stranded ligation.

Stiff T, Shtivelman E, Jeggo P, Kysela B. Stiff T, et al. DNA Repair (Amst). 2004 Mar 4;3(3):245-56. doi: 10.1016/j.dnarep.2003.11.001. DNA Repair (Amst). 2004. PMID: 15177040

6

Nbs1 is required for ATR-dependent phosphorylation events.

Stiff T, Reis C, Alderton GK, Woodbine L, O'Driscoll M, Jeggo PA. Stiff T, et al. EMBO J. 2005 Jan 12;24(1):199-208. doi: 10.1038/sj.emboj.7600504. Epub 2004 Dec 16. EMBO J. 2005. PMID: 15616588 Free PMC article.

7

ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling.

Stiff T, Walker SA, Cerosaletti K, Goodarzi AA, Petermann E, Concannon P, O'Driscoll M, Jeggo PA. Stiff T, et al. EMBO J. 2006 Dec 13;25(24):5775-82. doi: 10.1038/sj.emboj.7601446. Epub 2006 Nov 23. EMBO J. 2006. PMID: 17124492 Free PMC article.

8

Chromosome breakage after G2 checkpoint release.

Deckbar D, Birraux J, Krempler A, Tchouandong L, Beucher A, Walker S, Stiff T, Jeggo P, Löbrich M. Deckbar D, et al. Among authors: stiff t. J Cell Biol. 2007 Mar 12;176(6):749-55. doi: 10.1083/jcb.200612047. J Cell Biol. 2007. PMID: 17353355 Free PMC article.

9

Mutations in pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signaling.

Griffith E, Walker S, Martin CA, Vagnarelli P, Stiff T, Vernay B, Al Sanna N, Saggar A, Hamel B, Earnshaw WC, Jeggo PA, Jackson AP, O'Driscoll M. Griffith E, et al. Among authors: stiff t. Nat Genet. 2008 Feb;40(2):232-6. doi: 10.1038/ng.2007.80. Epub 2007 Dec 23. Nat Genet. 2008. PMID: 18157127 Free PMC article.

10

Replication independent ATR signalling leads to G2/M arrest requiring Nbs1, 53BP1 and MDC1.

Stiff T, Cerosaletti K, Concannon P, O'Driscoll M, Jeggo PA. Stiff T, et al. Hum Mol Genet. 2008 Oct 15;17(20):3247-53. doi: 10.1093/hmg/ddn220. Epub 2008 Jul 28. Hum Mol Genet. 2008. PMID: 18664457 Free PMC article.

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