Nerme V - Search Results

1

Characterization of a small molecule inhibitor of plasminogen activator inhibitor type 1 that accelerates the transition into the latent conformation.

Fjellström O, Deinum J, Sjögren T, Johansson C, Geschwindner S, Nerme V, Legnehed A, McPheat J, Olsson K, Bodin C, Paunovic A, Gustafsson D. Fjellström O, et al. Among authors: nerme v. J Biol Chem. 2013 Jan 11;288(2):873-85. doi: 10.1074/jbc.M112.371732. Epub 2012 Nov 15. J Biol Chem. 2013. PMID: 23155046 Free PMC article.

2

Creating novel activated factor XI inhibitors through fragment based lead generation and structure aided drug design.

Fjellström O, Akkaya S, Beisel HG, Eriksson PO, Erixon K, Gustafsson D, Jurva U, Kang D, Karis D, Knecht W, Nerme V, Nilsson I, Olsson T, Redzic A, Roth R, Sandmark J, Tigerström A, Öster L. Fjellström O, et al. Among authors: nerme v. PLoS One. 2015 Jan 28;10(1):e0113705. doi: 10.1371/journal.pone.0113705. eCollection 2015. PLoS One. 2015. PMID: 25629509 Free PMC article.

3

Anti-thrombotic effect of a PAI-1 inhibitor in rats given endotoxin.

Abrahamsson T, Nerme V, Strömqvist M, Akerblom B, Legnehed A, Pettersson K, Westin Eriksson A. Abrahamsson T, et al. Among authors: nerme v. Thromb Haemost. 1996 Jan;75(1):118-26. Thromb Haemost. 1996. PMID: 8713790

4

Local proCPU (TAFI) activation during thrombolytic treatment in a dog model of coronary artery thrombosis can be inhibited with a direct, small molecule thrombin inhibitor (melagatran).

Mattsson C, Björkman JA, Abrahamsson T, Nerme V, Schatteman K, Leurs J, Scharpé S, Hendriks D. Mattsson C, et al. Among authors: nerme v. Thromb Haemost. 2002 Apr;87(4):557-62. Thromb Haemost. 2002. PMID: 12008935

5

Inhibition of carboxypeptidase U (TAFIa) activity improves rt-PA induced thrombolysis in a dog model of coronary artery thrombosis.

Björkman JA, Abrahamsson TI, Nerme VK, Mattsson CJ. Björkman JA, et al. Among authors: nerme vk. Thromb Res. 2005;116(6):519-24. doi: 10.1016/j.thromres.2005.02.009. Epub 2005 Mar 17. Thromb Res. 2005. PMID: 16181987

6

PAI-1 inhibition enhances the lysis of the platelet-rich part of arterial-like thrombi formed in vitro. A comparative study using thrombi prepared from rat and human blood.

van Giezen JJ, Nerme V, Abrahamsson T. van Giezen JJ, et al. Among authors: nerme v. Blood Coagul Fibrinolysis. 1998 Jan;9(1):11-8. doi: 10.1097/00001721-199801000-00002. Blood Coagul Fibrinolysis. 1998. PMID: 9607114

7

The beta 1- and beta 2-adrenoceptor affinity and beta 1-blocking potency of S- and R-metoprolol.

Wahlund G, Nerme V, Abrahamsson T, Sjöquist PO. Wahlund G, et al. Among authors: nerme v. Br J Pharmacol. 1990 Mar;99(3):592-6. doi: 10.1111/j.1476-5381.1990.tb12974.x. Br J Pharmacol. 1990. PMID: 1970503 Free PMC article.

8

Chronic isoproterenol administration causes altered beta adrenoceptor-Gs-coupling in guinea pig lung.

Nerme V, Abrahamsson T, Vauquelin G. Nerme V, et al. J Pharmacol Exp Ther. 1990 Mar;252(3):1341-6. J Pharmacol Exp Ther. 1990. PMID: 2157000

9

The beta 1- and beta 2-adrenoceptor affinity of atenolol and metoprolol. A receptor-binding study performed with different radioligands in tissues from the rat, the guinea pig and man.

Abrahamsson T, Ek B, Nerme V. Abrahamsson T, et al. Among authors: nerme v. Biochem Pharmacol. 1988 Jan 15;37(2):203-8. doi: 10.1016/0006-2952(88)90718-6. Biochem Pharmacol. 1988. PMID: 2829913

10

Characterization of tight binding of isoprenaline and terbutaline to beta-adrenoceptors in lung membranes.

Nerme V, Abrahamsson T, Vauquelin G. Nerme V, et al. Arch Int Pharmacodyn Ther. 1989 Sep-Oct;301:51-65. Arch Int Pharmacodyn Ther. 1989. PMID: 2560366

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