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Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation.
Leeper NJ, Raiesdana A, Kojima Y, Kundu RK, Cheng H, Maegdefessel L, Toh R, Ahn GO, Ali ZA, Anderson DR, Miller CL, Roberts SC, Spin JM, de Almeida PE, Wu JC, Xu B, Cheng K, Quertermous M, Kundu S, Kortekaas KE, Berzin E, Downing KP, Dalman RL, Tsao PS, Schadt EE, Owens GK, Quertermous T. Leeper NJ, et al. Arterioscler Thromb Vasc Biol. 2013 Jan;33(1):e1-e10. doi: 10.1161/ATVBAHA.112.300399. Epub 2012 Nov 15. Arterioscler Thromb Vasc Biol. 2013. PMID: 23162013 Free PMC article.
Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis.
Chun HJ, Ali ZA, Kojima Y, Kundu RK, Sheikh AY, Agrawal R, Zheng L, Leeper NJ, Pearl NE, Patterson AJ, Anderson JP, Tsao PS, Lenardo MJ, Ashley EA, Quertermous T. Chun HJ, et al. Among authors: leeper nj. J Clin Invest. 2008 Oct;118(10):3343-54. doi: 10.1172/JCI34871. J Clin Invest. 2008. PMID: 18769630 Free PMC article.
Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation.
Leeper NJ, Tedesco MM, Kojima Y, Schultz GM, Kundu RK, Ashley EA, Tsao PS, Dalman RL, Quertermous T. Leeper NJ, et al. Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1329-35. doi: 10.1152/ajpheart.01341.2008. Epub 2009 Mar 20. Am J Physiol Heart Circ Physiol. 2009. PMID: 19304942 Free PMC article.
Endogenous regulation of cardiovascular function by apelin-APJ.
Charo DN, Ho M, Fajardo G, Kawana M, Kundu RK, Sheikh AY, Finsterbach TP, Leeper NJ, Ernst KV, Chen MM, Ho YD, Chun HJ, Bernstein D, Ashley EA, Quertermous T. Charo DN, et al. Among authors: leeper nj. Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1904-13. doi: 10.1152/ajpheart.00686.2009. Epub 2009 Sep 18. Am J Physiol Heart Circ Physiol. 2009. PMID: 19767528 Free PMC article.
Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development.
Maegdefessel L, Azuma J, Toh R, Merk DR, Deng A, Chin JT, Raaz U, Schoelmerich AM, Raiesdana A, Leeper NJ, McConnell MV, Dalman RL, Spin JM, Tsao PS. Maegdefessel L, et al. Among authors: leeper nj. J Clin Invest. 2012 Feb;122(2):497-506. doi: 10.1172/JCI61598. Epub 2012 Jan 24. J Clin Invest. 2012. PMID: 22269326 Free PMC article.
153 results