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Defective lysosomal proteolysis and axonal transport are early pathogenic events that worsen with age leading to increased APP metabolism and synaptic Abeta in transgenic APP/PS1 hippocampus.
Torres M, Jimenez S, Sanchez-Varo R, Navarro V, Trujillo-Estrada L, Sanchez-Mejias E, Carmona I, Davila JC, Vizuete M, Gutierrez A, Vitorica J. Torres M, et al. Among authors: vitorica j. Mol Neurodegener. 2012 Nov 22;7:59. doi: 10.1186/1750-1326-7-59. Mol Neurodegener. 2012. PMID: 23173743 Free PMC article.
Expression of alpha 5 GABAA receptor subunit in developing rat hippocampus.
Ramos B, Lopez-Tellez JF, Vela J, Baglietto-Vargas D, del Rio JC, Ruano D, Gutierrez A, Vitorica J. Ramos B, et al. Among authors: vitorica j. Brain Res Dev Brain Res. 2004 Jul 19;151(1-2):87-98. doi: 10.1016/j.devbrainres.2004.04.003. Brain Res Dev Brain Res. 2004. PMID: 15246695
Early neuropathology of somatostatin/NPY GABAergic cells in the hippocampus of a PS1xAPP transgenic model of Alzheimer's disease.
Ramos B, Baglietto-Vargas D, del Rio JC, Moreno-Gonzalez I, Santa-Maria C, Jimenez S, Caballero C, Lopez-Tellez JF, Khan ZU, Ruano D, Gutierrez A, Vitorica J. Ramos B, et al. Among authors: vitorica j. Neurobiol Aging. 2006 Nov;27(11):1658-72. doi: 10.1016/j.neurobiolaging.2005.09.022. Epub 2005 Nov 3. Neurobiol Aging. 2006. PMID: 16271420
Inter-individual variability in the expression of the mutated form of hPS1M146L determined the production of Abeta peptides in the PS1xAPP transgenic mice.
Caballero C, Jimenez S, Moreno-Gonzalez I, Baglietto-Vargas D, Sanchez-Varo R, Gavilan MP, Ramos B, Del Rio JC, Vizuete M, Gutierrez A, Ruano D, Vitorica J. Caballero C, et al. Among authors: vitorica j. J Neurosci Res. 2007 Mar;85(4):787-97. doi: 10.1002/jnr.21172. J Neurosci Res. 2007. PMID: 17243176
Molecular and cellular characterization of the age-related neuroinflammatory processes occurring in normal rat hippocampus: potential relation with the loss of somatostatin GABAergic neurons.
Gavilán MP, Revilla E, Pintado C, Castaño A, Vizuete ML, Moreno-González I, Baglietto-Vargas D, Sánchez-Varo R, Vitorica J, Gutiérrez A, Ruano D. Gavilán MP, et al. Among authors: vitorica j. J Neurochem. 2007 Nov;103(3):984-96. doi: 10.1111/j.1471-4159.2007.04787.x. Epub 2007 Jul 31. J Neurochem. 2007. PMID: 17666053 Free article.
Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic.
Jimenez S, Baglietto-Vargas D, Caballero C, Moreno-Gonzalez I, Torres M, Sanchez-Varo R, Ruano D, Vizuete M, Gutierrez A, Vitorica J. Jimenez S, et al. Among authors: vitorica j. J Neurosci. 2008 Nov 5;28(45):11650-61. doi: 10.1523/JNEUROSCI.3024-08.2008. J Neurosci. 2008. PMID: 18987201 Free PMC article.
114 results