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An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.
Lehmann SM, Krüger C, Park B, Derkow K, Rosenberger K, Baumgart J, Trimbuch T, Eom G, Hinz M, Kaul D, Habbel P, Kälin R, Franzoni E, Rybak A, Nguyen D, Veh R, Ninnemann O, Peters O, Nitsch R, Heppner FL, Golenbock D, Schott E, Ploegh HL, Wulczyn FG, Lehnardt S. Lehmann SM, et al. Nat Neurosci. 2012 Jun;15(6):827-35. doi: 10.1038/nn.3113. Nat Neurosci. 2012. PMID: 22610069
Essential role of interleukin-6 in post-stroke angiogenesis.
Gertz K, Kronenberg G, Kälin RE, Baldinger T, Werner C, Balkaya M, Eom GD, Hellmann-Regen J, Kröber J, Miller KR, Lindauer U, Laufs U, Dirnagl U, Heppner FL, Endres M. Gertz K, et al. Among authors: kalin re. Brain. 2012 Jun;135(Pt 6):1964-80. doi: 10.1093/brain/aws075. Epub 2012 Apr 3. Brain. 2012. PMID: 22492561 Free PMC article.
CNS myeloid cells critically regulate heat hyperalgesia.
Kälin S, Miller KR, Kälin RE, Jendrach M, Witzel C, Heppner FL. Kälin S, et al. Among authors: kalin re. J Clin Invest. 2018 Jul 2;128(7):2774-2786. doi: 10.1172/JCI95305. Epub 2018 May 21. J Clin Invest. 2018. PMID: 29634489 Free PMC article.
Neuroprotective function for ramified microglia in hippocampal excitotoxicity.
Vinet J, Weering HR, Heinrich A, Kälin RE, Wegner A, Brouwer N, Heppner FL, Rooijen Nv, Boddeke HW, Biber K. Vinet J, et al. Among authors: kalin re. J Neuroinflammation. 2012 Jan 31;9:27. doi: 10.1186/1742-2094-9-27. J Neuroinflammation. 2012. PMID: 22293457 Free PMC article.
Apelin Controls Angiogenesis-Dependent Glioblastoma Growth.
Frisch A, Kälin S, Monk R, Radke J, Heppner FL, Kälin RE. Frisch A, et al. Among authors: kalin re, kalin s. Int J Mol Sci. 2020 Jun 11;21(11):4179. doi: 10.3390/ijms21114179. Int J Mol Sci. 2020. PMID: 32545380 Free PMC article.
Gliomas induce and exploit microglial MT1-MMP expression for tumor expansion.
Markovic DS, Vinnakota K, Chirasani S, Synowitz M, Raguet H, Stock K, Sliwa M, Lehmann S, Kälin R, van Rooijen N, Holmbeck K, Heppner FL, Kiwit J, Matyash V, Lehnardt S, Kaminska B, Glass R, Kettenmann H. Markovic DS, et al. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12530-5. doi: 10.1073/pnas.0804273106. Epub 2009 Jul 15. Proc Natl Acad Sci U S A. 2009. PMID: 19617536 Free PMC article.
33 results