Aristoff PA - Search Results

1

Characterization of B16 melanoma cells resistant to the CC-1065 analogue U-71,184.

Moy BC, Petzold GL, Badiner GJ, Kelly RC, Aristoff PA, Adams EG, Li LH, Bhuyan BK. Moy BC, et al. Among authors: aristoff pa. Cancer Res. 1990 Apr 15;50(8):2485-92. Cancer Res. 1990. PMID: 2317831

2

K252a, KT5720, KT5926, and U98017 support paclitaxel (taxol)-dependent cells and synergize with paclitaxel.

Abraham I, Wolf CL, Sampson KE, Laborde AL, Shelly JA, Aristoff PA, Skulnick HI. Abraham I, et al. Among authors: aristoff pa. Cancer Res. 1994 Nov 15;54(22):5889-94. Cancer Res. 1994. PMID: 7954419

3

Molecular basis for sequence-specific DNA alkylation by CC-1065.

Hurley LH, Lee CS, McGovren JP, Warpehoski MA, Mitchell MA, Kelly RC, Aristoff PA. Hurley LH, et al. Among authors: aristoff pa. Biochemistry. 1988 May 17;27(10):3886-92. doi: 10.1021/bi00410a054. Biochemistry. 1988. PMID: 3408734

4

Reaction of CC-1065 and select synthetic analogs with DNA.

Hurley LH, Lee CS, McGovren JP, Warpehoski MA, Mitchell MA, Kelly RC, Aristoff PA. Hurley LH, et al. Among authors: aristoff pa. Biochem Pharmacol. 1988 May 1;37(9):1795-6. doi: 10.1016/0006-2952(88)90450-9. Biochem Pharmacol. 1988. PMID: 3377837 No abstract available.

5

Sequence-selective guanine reactivity by duocarmycin A.

Mitchell MA, Weiland KL, Aristoff PA, Johnson PD, Dooley TP. Mitchell MA, et al. Among authors: aristoff pa. Chem Res Toxicol. 1993 Jul-Aug;6(4):421-4. doi: 10.1021/tx00034a005. Chem Res Toxicol. 1993. PMID: 8374036

6

Antibacterial oxazolidinones possessing a novel C-5 side chain. (5R)-trans-3-[3-Fluoro-4- (1-oxotetrahydrothiopyran-4-yl)phenyl]-2- oxooxazolidine-5-carboxylic acid amide (PF-00422602), a new lead compound.

Poel TJ, Thomas RC, Adams WJ, Aristoff PA, Barbachyn MR, Boyer FE, Brieland J, Brideau R, Brodfuehrer J, Brown AP, Choy AL, Dermyer M, Dority M, Ford CW, Gadwood RC, Hanna D, Hongliang C, Huband MD, Huber C, Kelly R, Kim JY, Martin JP Jr, Pagano PJ, Ross D, Skerlos L, Sulavik MC, Zhu T, Zurenko GE, Prasad JV. Poel TJ, et al. Among authors: aristoff pa. J Med Chem. 2007 Nov 29;50(24):5886-9. doi: 10.1021/jm070708p. Epub 2007 Nov 8. J Med Chem. 2007. PMID: 17988109

7

Nonnucleoside reverse transcriptase inhibitors that potently and specifically block human immunodeficiency virus type 1 replication.

Romero DL, Busso M, Tan CK, Reusser F, Palmer JR, Poppe SM, Aristoff PA, Downey KM, So AG, Resnick L, et al. Romero DL, et al. Among authors: aristoff pa. Proc Natl Acad Sci U S A. 1991 Oct 1;88(19):8806-10. doi: 10.1073/pnas.88.19.8806. Proc Natl Acad Sci U S A. 1991. PMID: 1717988 Free PMC article.

8

Synthesis and biochemical evaluation of the CBI-PDE-I-dimer, a benzannelated analog of (+)-CC-1065 that also produces delayed toxicity in mice.

Aristoff PA, Johnson PD, Sun D, Hurley LH. Aristoff PA, et al. J Med Chem. 1993 Jul 9;36(14):1956-63. doi: 10.1021/jm00066a004. J Med Chem. 1993. PMID: 8336335

9

Kinetic studies with the non-nucleoside human immunodeficiency virus type-1 reverse transcriptase inhibitor U-90152E.

Althaus IW, Chou JJ, Gonzales AJ, Deibel MR, Chou KC, Kezdy FJ, Romero DL, Thomas RC, Aristoff PA, Tarpley WG, et al. Althaus IW, et al. Among authors: aristoff pa. Biochem Pharmacol. 1994 Jun 1;47(11):2017-28. doi: 10.1016/0006-2952(94)90077-9. Biochem Pharmacol. 1994. PMID: 7516658

10

Enzymatic kinetic studies with the non-nucleoside HIV reverse transcriptase inhibitor U-9843.

Althaus IW, LeMay RJ, Gonzales AJ, Deibel MR, Sharma SK, Kezdy FJ, Resnick L, Busso ME, Aristoff PA, Reusser F. Althaus IW, et al. Among authors: aristoff pa. Experientia. 1992 Dec 1;48(11-12):1127-32. doi: 10.1007/BF01948005. Experientia. 1992. PMID: 1282106

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