Tepe JJ - Search Results

1

Noncompetitive modulation of the proteasome by imidazoline scaffolds overcomes bortezomib resistance and delays MM tumor growth in vivo.

Lansdell TA, Hurchla MA, Xiang J, Hovde S, Weilbaecher KN, Henry RW, Tepe JJ. Lansdell TA, et al. Among authors: tepe jj. ACS Chem Biol. 2013 Mar 15;8(3):578-87. doi: 10.1021/cb300568r. Epub 2012 Dec 11. ACS Chem Biol. 2013. PMID: 23198928 Free PMC article.

2

Inhibition of cytokine production by hymenialdisine derivatives.

Sharma V, Lansdell TA, Jin G, Tepe JJ. Sharma V, et al. Among authors: tepe jj. J Med Chem. 2004 Jul 1;47(14):3700-3. doi: 10.1021/jm040013d. J Med Chem. 2004. PMID: 15214798

3

Sensitization of tumor cells toward chemotherapy: enhancing the efficacy of camptothecin with imidazolines.

Sharma V, Lansdell TA, Peddibhotla S, Tepe JJ. Sharma V, et al. Among authors: tepe jj. Chem Biol. 2004 Dec;11(12):1689-99. doi: 10.1016/j.chembiol.2004.10.006. Chem Biol. 2004. PMID: 15610853

4

Sensitization of cancer cells to DNA damaging agents by imidazolines.

Sharma V, Peddibhotla S, Tepe JJ. Sharma V, et al. Among authors: tepe jj. J Am Chem Soc. 2006 Jul 19;128(28):9137-43. doi: 10.1021/ja060273f. J Am Chem Soc. 2006. PMID: 16834387

5

Nuclear factor-kappaB mediated inhibition of cytokine production by imidazoline scaffolds.

Kahlon DK, Lansdell TA, Fisk JS, Hupp CD, Friebe TL, Hovde S, Jones AD, Dyer RD, Henry RW, Tepe JJ. Kahlon DK, et al. Among authors: tepe jj. J Med Chem. 2009 Mar 12;52(5):1302-9. doi: 10.1021/jm8013162. J Med Chem. 2009. PMID: 19220017

6

Structural-activity relationship study of highly-functionalized imidazolines as potent inhibitors of nuclear transcription factor-kappaB mediated IL-6 production.

Kahlon DK, Lansdell TA, Fisk JS, Tepe JJ. Kahlon DK, et al. Among authors: tepe jj. Bioorg Med Chem. 2009 Apr 15;17(8):3093-103. doi: 10.1016/j.bmc.2009.03.002. Epub 2009 Mar 9. Bioorg Med Chem. 2009. PMID: 19328000

7

Radioprotection by hymenialdisine-derived checkpoint kinase 2 inhibitors.

Nguyen TN, Saleem RS, Luderer MJ, Hovde S, Henry RW, Tepe JJ. Nguyen TN, et al. Among authors: tepe jj. ACS Chem Biol. 2012 Jan 20;7(1):172-84. doi: 10.1021/cb200320c. Epub 2011 Oct 24. ACS Chem Biol. 2012. PMID: 22004065

8

Synthesis and evaluation of debromohymenialdisine-derived Chk2 inhibitors.

Saleem RS, Lansdell TA, Tepe JJ. Saleem RS, et al. Among authors: tepe jj. Bioorg Med Chem. 2012 Feb 15;20(4):1475-81. doi: 10.1016/j.bmc.2011.12.054. Epub 2012 Jan 11. Bioorg Med Chem. 2012. PMID: 22285028

9

Palau'amine and related oroidin alkaloids dibromophakellin and dibromophakellstatin inhibit the human 20S proteasome.

Lansdell TA, Hewlett NM, Skoumbourdis AP, Fodor MD, Seiple IB, Su S, Baran PS, Feldman KS, Tepe JJ. Lansdell TA, et al. Among authors: tepe jj. J Nat Prod. 2012 May 25;75(5):980-5. doi: 10.1021/np300231f. Epub 2012 May 16. J Nat Prod. 2012. PMID: 22591513 Free PMC article.

10

Attenuation of collagen-induced arthritis by orally available imidazoline-based NF-κB inhibitors.

Lansdell TA, O'Reilly S, Woolliscroft T, Azevedo LM, Kahlon DK, Hovde S, McCormick JJ, Henry RW, Cornicelli JA, Tepe JJ. Lansdell TA, et al. Among authors: tepe jj. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4816-9. doi: 10.1016/j.bmcl.2012.05.056. Epub 2012 May 18. Bioorg Med Chem Lett. 2012. PMID: 22682057

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