Sanhueza M - Search Results

1

A genome-scale RNA-interference screen identifies RRAS signaling as a pathologic feature of Huntington's disease.

Miller JP, Yates BE, Al-Ramahi I, Berman AE, Sanhueza M, Kim E, de Haro M, DeGiacomo F, Torcassi C, Holcomb J, Gafni J, Mooney SD, Botas J, Ellerby LM, Hughes RE. Miller JP, et al. Among authors: sanhueza m. PLoS Genet. 2012;8(11):e1003042. doi: 10.1371/journal.pgen.1003042. Epub 2012 Nov 29. PLoS Genet. 2012. PMID: 23209424 Free PMC article.

2

Matrix metalloproteinases are modifiers of huntingtin proteolysis and toxicity in Huntington's disease.

Miller JP, Holcomb J, Al-Ramahi I, de Haro M, Gafni J, Zhang N, Kim E, Sanhueza M, Torcassi C, Kwak S, Botas J, Hughes RE, Ellerby LM. Miller JP, et al. Among authors: sanhueza m. Neuron. 2010 Jul 29;67(2):199-212. doi: 10.1016/j.neuron.2010.06.021. Neuron. 2010. PMID: 20670829 Free PMC article.

3

Network analyses reveal novel aspects of ALS pathogenesis.

Sanhueza M, Chai A, Smith C, McCray BA, Simpson TI, Taylor JP, Pennetta G. Sanhueza M, et al. PLoS Genet. 2015 Mar 31;11(3):e1005107. doi: 10.1371/journal.pgen.1005107. eCollection 2015 Mar. PLoS Genet. 2015. PMID: 25826266 Free PMC article.

4

Mitochondria and Calcium Regulation as Basis of Neurodegeneration Associated With Aging.

Müller M, Ahumada-Castro U, Sanhueza M, Gonzalez-Billault C, Court FA, Cárdenas C. Müller M, et al. Among authors: sanhueza m. Front Neurosci. 2018 Jul 13;12:470. doi: 10.3389/fnins.2018.00470. eCollection 2018. Front Neurosci. 2018. PMID: 30057523 Free PMC article.

5

Increased levels of phosphoinositides cause neurodegeneration in a Drosophila model of amyotrophic lateral sclerosis.

Forrest S, Chai A, Sanhueza M, Marescotti M, Parry K, Georgiev A, Sahota V, Mendez-Castro R, Pennetta G. Forrest S, et al. Among authors: sanhueza m. Hum Mol Genet. 2013 Jul 1;22(13):2689-704. doi: 10.1093/hmg/ddt118. Epub 2013 Mar 13. Hum Mol Genet. 2013. PMID: 23492670 Free PMC article.

6

Why Quantification Matters: Characterization of Phenotypes at the Drosophila Larval Neuromuscular Junction.

Sanhueza M, Kubasik-Thayil A, Pennetta G. Sanhueza M, et al. J Vis Exp. 2016 May 12;(111):53821. doi: 10.3791/53821. J Vis Exp. 2016. PMID: 27213489 Free PMC article.

7

Gain-of-function mutations in the ALS8 causative gene VAPB have detrimental effects on neurons and muscles.

Sanhueza M, Zechini L, Gillespie T, Pennetta G. Sanhueza M, et al. Biol Open. 2014 Jan 15;3(1):59-71. doi: 10.1242/bio.20137070. Biol Open. 2014. PMID: 24326187 Free PMC article.

8

Axonal Degeneration during Aging and Its Functional Role in Neurodegenerative Disorders.

Salvadores N, Sanhueza M, Manque P, Court FA. Salvadores N, et al. Among authors: sanhueza m. Front Neurosci. 2017 Sep 4;11:451. doi: 10.3389/fnins.2017.00451. eCollection 2017. Front Neurosci. 2017. PMID: 28928628 Free PMC article. Review.

9

The Mitochondrial Unfolded Protein Response: A Hinge Between Healthy and Pathological Aging.

Muñoz-Carvajal F, Sanhueza M. Muñoz-Carvajal F, et al. Among authors: sanhueza m. Front Aging Neurosci. 2020 Sep 11;12:581849. doi: 10.3389/fnagi.2020.581849. eCollection 2020. Front Aging Neurosci. 2020. PMID: 33061907 Free PMC article. Review.

10

Filtering of Data-Driven Gene Regulatory Networks Using Drosophila melanogaster as a Case Study.

Cuesta-Astroz Y, Gischkow Rucatti G, Murgas L, SanMartín CD, Sanhueza M, Martin AJM. Cuesta-Astroz Y, et al. Among authors: sanhueza m. Front Genet. 2021 Jul 28;12:649764. doi: 10.3389/fgene.2021.649764. eCollection 2021. Front Genet. 2021. PMID: 34394179 Free PMC article.

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