Keune WJ - Search Results

1

PtdIns5P is an oxidative stress-induced second messenger that regulates PKB activation.

Jones DR, Foulger R, Keune WJ, Bultsma Y, Divecha N. Jones DR, et al. Among authors: keune wj. FASEB J. 2013 Apr;27(4):1644-56. doi: 10.1096/fj.12-218842. Epub 2012 Dec 14. FASEB J. 2013. PMID: 23241309

2

Regulation of phosphatidylinositol-5-phosphate signaling by Pin1 determines sensitivity to oxidative stress.

Keune WJ, Jones DR, Bultsma Y, Sommer L, Zhou XZ, Lu KP, Divecha N. Keune WJ, et al. Sci Signal. 2012 Nov 27;5(252):ra86. doi: 10.1126/scisignal.2003223. Sci Signal. 2012. PMID: 23193159

3

PtdIns5P and Pin1 in oxidative stress signaling.

Keune WJ, Jones DR, Divecha N. Keune WJ, et al. Adv Biol Regul. 2013 May;53(2):179-89. doi: 10.1016/j.jbior.2013.02.001. Epub 2013 Mar 13. Adv Biol Regul. 2013. PMID: 23602596 Review.

4

Collaboration of AMPK and PKC to induce phosphorylation of Ser413 on PIP5K1B resulting in decreased kinase activity and reduced PtdIns(4,5)P2 synthesis in response to oxidative stress and energy restriction.

van den Bout I, Jones DR, Shah ZH, Halstead JR, Keune WJ, Mohammed S, D'Santos CS, Divecha N. van den Bout I, et al. Among authors: keune wj. Biochem J. 2013 Nov 1;455(3):347-58. doi: 10.1042/BJ20130259. Biochem J. 2013. PMID: 23909401

5

The hexosamine biosynthesis pathway and O-GlcNAcylation maintain insulin-stimulated PI3K-PKB phosphorylation and tumour cell growth after short-term glucose deprivation.

Jones DR, Keune WJ, Anderson KE, Stephens LR, Hawkins PT, Divecha N. Jones DR, et al. Among authors: keune wj. FEBS J. 2014 Aug;281(16):3591-608. doi: 10.1111/febs.12879. Epub 2014 Jul 14. FEBS J. 2014. PMID: 24938479 Free article.

6

Phosphoinositide signalling in the nucleus.

Keune Wj, Bultsma Y, Sommer L, Jones D, Divecha N. Keune Wj, et al. Adv Enzyme Regul. 2011;51(1):91-9. doi: 10.1016/j.advenzreg.2010.09.009. Epub 2010 Oct 28. Adv Enzyme Regul. 2011. PMID: 21035491 Review. No abstract available.

7

Methods for the determination of the mass of nuclear PtdIns4P, PtdIns5P, and PtdIns(4,5)P2.

Jones DR, Bultsma Y, Keune WJ, Divecha N. Jones DR, et al. Among authors: keune wj. Methods Mol Biol. 2009;462:75-88. doi: 10.1007/978-1-60327-115-8_5. Methods Mol Biol. 2009. PMID: 19160662

8

PIP4K and the role of nuclear phosphoinositides in tumour suppression.

Fiume R, Stijf-Bultsma Y, Shah ZH, Keune WJ, Jones DR, Jude JG, Divecha N. Fiume R, et al. Among authors: keune wj. Biochim Biophys Acta. 2015 Jun;1851(6):898-910. doi: 10.1016/j.bbalip.2015.02.014. Epub 2015 Feb 26. Biochim Biophys Acta. 2015. PMID: 25728392 Review.

9

Nuclear PtdIns5P as a transducer of stress signaling: an in vivo role for PIP4Kbeta.

Jones DR, Bultsma Y, Keune WJ, Halstead JR, Elouarrat D, Mohammed S, Heck AJ, D'Santos CS, Divecha N. Jones DR, et al. Among authors: keune wj. Mol Cell. 2006 Sep 1;23(5):685-95. doi: 10.1016/j.molcel.2006.07.014. Mol Cell. 2006. PMID: 16949365 Free article.

10

PIP4Kbeta interacts with and modulates nuclear localization of the high-activity PtdIns5P-4-kinase isoform PIP4Kalpha.

Bultsma Y, Keune WJ, Divecha N. Bultsma Y, et al. Among authors: keune wj. Biochem J. 2010 Sep 1;430(2):223-35. doi: 10.1042/BJ20100341. Biochem J. 2010. PMID: 20583997

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