Harper MT - Search Results

1

Dysfunction of the PI3 kinase/Rap1/integrin α(IIb)β(3) pathway underlies ex vivo platelet hypoactivity in essential thrombocythemia.

Moore SF, Hunter RW, Harper MT, Savage JS, Siddiq S, Westbury SK, Poole AW, Mumford AD, Hers I. Moore SF, et al. Among authors: harper mt. Blood. 2013 Feb 14;121(7):1209-19. doi: 10.1182/blood-2012-05-431288. Epub 2012 Dec 13. Blood. 2013. PMID: 23243278 Free article.

2

A role for cofilin in the activation of store-operated calcium entry by de novo conformational coupling in human platelets.

Redondo PC, Harper MT, Rosado JA, Sage SO. Redondo PC, et al. Among authors: harper mt. Blood. 2006 Feb 1;107(3):973-9. doi: 10.1182/blood-2005-05-2015. Epub 2005 Oct 18. Blood. 2006. PMID: 16234361 Free article.

3

Isoform-specific functions of protein kinase C: the platelet paradigm.

Harper MT, Poole AW. Harper MT, et al. Biochem Soc Trans. 2007 Nov;35(Pt 5):1005-8. doi: 10.1042/BST0351005. Biochem Soc Trans. 2007. PMID: 17956264 Review.

4

The PKB inhibitor Akti-1/2 potentiates PAR-1-mediated platelet function independently of its ability to block PKB.

Hunter RW, Harper MT, Hers I. Hunter RW, et al. Among authors: harper mt. J Thromb Haemost. 2008 Nov;6(11):1923-32. doi: 10.1111/j.1538-7836.2008.03140.x. Epub 2008 Aug 28. J Thromb Haemost. 2008. PMID: 18761726 Free article.

5

Genetic analysis of the role of protein kinase Ctheta in platelet function and thrombus formation.

Hall KJ, Harper MT, Gilio K, Cosemans JM, Heemskerk JW, Poole AW. Hall KJ, et al. Among authors: harper mt. PLoS One. 2008 Sep 25;3(9):e3277. doi: 10.1371/journal.pone.0003277. PLoS One. 2008. PMID: 18815612 Free PMC article.

6

PKCalpha regulates platelet granule secretion and thrombus formation in mice.

Konopatskaya O, Gilio K, Harper MT, Zhao Y, Cosemans JM, Karim ZA, Whiteheart SW, Molkentin JD, Verkade P, Watson SP, Heemskerk JW, Poole AW. Konopatskaya O, et al. Among authors: harper mt. J Clin Invest. 2009 Feb;119(2):399-407. doi: 10.1172/JCI34665. Epub 2009 Jan 19. J Clin Invest. 2009. PMID: 19147982 Free PMC article.

7

PKCtheta in platelet activation.

Harper MT, Poole AW. Harper MT, et al. Blood. 2009 Jul 9;114(2):489-91; author reply 491-2. doi: 10.1182/blood-2009-03-208454. Blood. 2009. PMID: 19589937 Free article. No abstract available.

8

Canonical Wnt signaling negatively regulates platelet function.

Steele BM, Harper MT, Macaulay IC, Morrell CN, Perez-Tamayo A, Foy M, Habas R, Poole AW, Fitzgerald DJ, Maguire PB. Steele BM, et al. Among authors: harper mt. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19836-41. doi: 10.1073/pnas.0906268106. Epub 2009 Nov 9. Proc Natl Acad Sci U S A. 2009. PMID: 19901330 Free PMC article.

9

RGD-ligand mimetic antagonists of integrin alphaIIbbeta3 paradoxically enhance GPVI-induced human platelet activation.

Jones ML, Harper MT, Aitken EW, Williams CM, Poole AW. Jones ML, et al. Among authors: harper mt. J Thromb Haemost. 2010 Mar;8(3):567-76. doi: 10.1111/j.1538-7836.2009.03719.x. Epub 2009 Dec 11. J Thromb Haemost. 2010. PMID: 20002543 Free article.

10

Diverse functions of protein kinase C isoforms in platelet activation and thrombus formation.

Harper MT, Poole AW. Harper MT, et al. J Thromb Haemost. 2010 Mar;8(3):454-62. doi: 10.1111/j.1538-7836.2009.03722.x. Epub 2009 Dec 11. J Thromb Haemost. 2010. PMID: 20002545 Free article. Review.

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