He X - Search Results

1

Germline PIK3CA and AKT1 mutations in Cowden and Cowden-like syndromes.

Orloff MS, He X, Peterson C, Chen F, Chen JL, Mester JL, Eng C. Orloff MS, et al. Among authors: he x. Am J Hum Genet. 2013 Jan 10;92(1):76-80. doi: 10.1016/j.ajhg.2012.10.021. Epub 2012 Dec 13. Am J Hum Genet. 2013. PMID: 23246288 Free PMC article.

2

Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines.

Wang Y, Romigh T, He X, Orloff MS, Silverman RH, Heston WD, Eng C. Wang Y, et al. Among authors: he x. Hum Mol Genet. 2010 Nov 15;19(22):4319-29. doi: 10.1093/hmg/ddq354. Epub 2010 Aug 20. Hum Mol Genet. 2010. PMID: 20729295 Free PMC article.

3

Naturally occurring germline and tumor-associated mutations within the ATP-binding motifs of PTEN lead to oxidative damage of DNA associated with decreased nuclear p53.

He X, Ni Y, Wang Y, Romigh T, Eng C. He X, et al. Hum Mol Genet. 2011 Jan 1;20(1):80-9. doi: 10.1093/hmg/ddq434. Epub 2010 Oct 6. Hum Mol Genet. 2011. PMID: 20926450 Free PMC article.

4

Germline SDHx variants modify breast and thyroid cancer risks in Cowden and Cowden-like syndrome via FAD/NAD-dependant destabilization of p53.

Ni Y, He X, Chen J, Moline J, Mester J, Orloff MS, Ringel MD, Eng C. Ni Y, et al. Among authors: he x. Hum Mol Genet. 2012 Jan 15;21(2):300-10. doi: 10.1093/hmg/ddr459. Epub 2011 Oct 6. Hum Mol Genet. 2012. PMID: 21979946 Free PMC article.

5

GATA2 negatively regulates PTEN by preventing nuclear translocation of androgen receptor and by androgen-independent suppression of PTEN transcription in breast cancer.

Wang Y, He X, Ngeow J, Eng C. Wang Y, et al. Among authors: he x. Hum Mol Genet. 2012 Feb 1;21(3):569-76. doi: 10.1093/hmg/ddr491. Epub 2011 Oct 21. Hum Mol Genet. 2012. PMID: 22021428

6

Utility of PTEN protein dosage in predicting for underlying germline PTEN mutations among patients presenting with thyroid cancer and Cowden-like phenotypes.

Ngeow J, He X, Mester JL, Lei J, Romigh T, Orloff MS, Milas M, Eng C. Ngeow J, et al. Among authors: he x. J Clin Endocrinol Metab. 2012 Dec;97(12):E2320-7. doi: 10.1210/jc.2012-2944. Epub 2012 Oct 12. J Clin Endocrinol Metab. 2012. PMID: 23066114 Free PMC article.

7

Cowden syndrome-related mutations in PTEN associate with enhanced proteasome activity.

He X, Arrotta N, Radhakrishnan D, Wang Y, Romigh T, Eng C. He X, et al. Cancer Res. 2013 May 15;73(10):3029-40. doi: 10.1158/0008-5472.CAN-12-3811. Epub 2013 Mar 8. Cancer Res. 2013. PMID: 23475934 Free PMC article.

8

Cowden syndrome-associated germline SDHD variants alter PTEN nuclear translocation through SRC-induced PTEN oxidation.

Yu W, He X, Ni Y, Ngeow J, Eng C. Yu W, et al. Among authors: he x. Hum Mol Genet. 2015 Jan 1;24(1):142-53. doi: 10.1093/hmg/ddu425. Epub 2014 Aug 22. Hum Mol Genet. 2015. PMID: 25149476 Free PMC article.

9

Differential regulation of PTEN expression by androgen receptor in prostate and breast cancers.

Wang Y, Romigh T, He X, Tan MH, Orloff MS, Silverman RH, Heston WD, Eng C. Wang Y, et al. Among authors: he x. Oncogene. 2011 Oct 20;30(42):4327-38. doi: 10.1038/onc.2011.144. Epub 2011 May 2. Oncogene. 2011. PMID: 21532617

10

Resveratrol enhances the anti-tumor activity of the mTOR inhibitor rapamycin in multiple breast cancer cell lines mainly by suppressing rapamycin-induced AKT signaling.

He X, Wang Y, Zhu J, Orloff M, Eng C. He X, et al. Cancer Lett. 2011 Feb 28;301(2):168-76. doi: 10.1016/j.canlet.2010.11.012. Epub 2010 Dec 17. Cancer Lett. 2011. PMID: 21168265

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

28,810 results

Search Page

Filters