Xie M - Search Results

1

Deletion of TAK1 in the myeloid lineage results in the spontaneous development of myelomonocytic leukemia in mice.

Lamothe B, Lai Y, Hur L, Orozco NM, Wang J, Campos AD, Xie M, Schneider MD, Lockworth CR, Jakacky J, Tran D, Ho M, Dawud S, Dong C, Lin HK, Hu P, Estrov Z, Bueso-Ramos CE, Darnay BG. Lamothe B, et al. Among authors: xie m. PLoS One. 2012;7(12):e51228. doi: 10.1371/journal.pone.0051228. Epub 2012 Dec 10. PLoS One. 2012. PMID: 23251462 Free PMC article.

2

TAK1 is essential for osteoclast differentiation and is an important modulator of cell death by apoptosis and necroptosis.

Lamothe B, Lai Y, Xie M, Schneider MD, Darnay BG. Lamothe B, et al. Among authors: xie m. Mol Cell Biol. 2013 Feb;33(3):582-95. doi: 10.1128/MCB.01225-12. Epub 2012 Nov 19. Mol Cell Biol. 2013. PMID: 23166301 Free PMC article.

3

Essential role of TAK1 in thymocyte development and activation.

Liu HH, Xie M, Schneider MD, Chen ZJ. Liu HH, et al. Among authors: xie m. Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11677-82. doi: 10.1073/pnas.0603089103. Epub 2006 Jul 20. Proc Natl Acad Sci U S A. 2006. PMID: 16857737 Free PMC article.

4

The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function.

Wan YY, Chi H, Xie M, Schneider MD, Flavell RA. Wan YY, et al. Among authors: xie m. Nat Immunol. 2006 Aug;7(8):851-8. doi: 10.1038/ni1355. Epub 2006 Jun 25. Nat Immunol. 2006. PMID: 16799562

5

A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway.

Xie M, Zhang D, Dyck JR, Li Y, Zhang H, Morishima M, Mann DL, Taffet GE, Baldini A, Khoury DS, Schneider MD. Xie M, et al. Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17378-83. doi: 10.1073/pnas.0604708103. Epub 2006 Nov 3. Proc Natl Acad Sci U S A. 2006. PMID: 17085580 Free PMC article.

6

Phosphorylation of Thr-178 and Thr-184 in the TAK1 T-loop is required for interleukin (IL)-1-mediated optimal NFkappaB and AP-1 activation as well as IL-6 gene expression.

Yu Y, Ge N, Xie M, Sun W, Burlingame S, Pass AK, Nuchtern JG, Zhang D, Fu S, Schneider MD, Fan J, Yang J. Yu Y, et al. Among authors: xie m. J Biol Chem. 2008 Sep 5;283(36):24497-505. doi: 10.1074/jbc.M802825200. Epub 2008 Jul 10. J Biol Chem. 2008. PMID: 18617512 Free PMC article.

7

TAK1 is an essential regulator of BMP signalling in cartilage.

Shim JH, Greenblatt MB, Xie M, Schneider MD, Zou W, Zhai B, Gygi S, Glimcher LH. Shim JH, et al. Among authors: xie m. EMBO J. 2009 Jul 22;28(14):2028-41. doi: 10.1038/emboj.2009.162. Epub 2009 Jun 18. EMBO J. 2009. PMID: 19536134 Free PMC article.

8

Ablation of Tak1 in osteoclast progenitor leads to defects in skeletal growth and bone remodeling in mice.

Qi B, Cong Q, Li P, Ma G, Guo X, Yeh J, Xie M, Schneider MD, Liu H, Li B. Qi B, et al. Among authors: xie m. Sci Rep. 2014 Nov 24;4:7158. doi: 10.1038/srep07158. Sci Rep. 2014. PMID: 25418008 Free PMC article.

9

Microtubules regulate focal adhesion dynamics through MAP4K4.

Yue J, Xie M, Gou X, Lee P, Schneider MD, Wu X. Yue J, et al. Among authors: xie m. Dev Cell. 2014 Dec 8;31(5):572-85. doi: 10.1016/j.devcel.2014.10.025. Dev Cell. 2014. PMID: 25490267 Free PMC article.

10

Activation of Rho-associated coiled-coil protein kinase 1 (ROCK-1) by caspase-3 cleavage plays an essential role in cardiac myocyte apoptosis.

Chang J, Xie M, Shah VR, Schneider MD, Entman ML, Wei L, Schwartz RJ. Chang J, et al. Among authors: xie m. Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14495-500. doi: 10.1073/pnas.0601911103. Epub 2006 Sep 18. Proc Natl Acad Sci U S A. 2006. PMID: 16983089 Free PMC article.

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