Gu C - Search Results

1

The highly conserved layer-3 component of the HIV-1 gp120 inner domain is critical for CD4-required conformational transitions.

Désormeaux A, Coutu M, Medjahed H, Pacheco B, Herschhorn A, Gu C, Xiang SH, Mao Y, Sodroski J, Finzi A. Désormeaux A, et al. Among authors: gu c. J Virol. 2013 Mar;87(5):2549-62. doi: 10.1128/JVI.03104-12. Epub 2012 Dec 19. J Virol. 2013. PMID: 23255784 Free PMC article.

2

A broad HIV-1 inhibitor blocks envelope glycoprotein transitions critical for entry.

Herschhorn A, Gu C, Espy N, Richard J, Finzi A, Sodroski JG. Herschhorn A, et al. Among authors: gu c. Nat Chem Biol. 2014 Oct;10(10):845-52. doi: 10.1038/nchembio.1623. Epub 2014 Aug 31. Nat Chem Biol. 2014. PMID: 25174000 Free PMC article.

3

Release of gp120 Restraints Leads to an Entry-Competent Intermediate State of the HIV-1 Envelope Glycoproteins.

Herschhorn A, Ma X, Gu C, Ventura JD, Castillo-Menendez L, Melillo B, Terry DS, Smith AB 3rd, Blanchard SC, Munro JB, Mothes W, Finzi A, Sodroski J. Herschhorn A, et al. Among authors: gu c. mBio. 2016 Oct 25;7(5):e01598-16. doi: 10.1128/mBio.01598-16. mBio. 2016. PMID: 27795397 Free PMC article.

4

Residues in the gp41 Ectodomain Regulate HIV-1 Envelope Glycoprotein Conformational Transitions Induced by gp120-Directed Inhibitors.

Pacheco B, Alsahafi N, Debbeche O, Prévost J, Ding S, Chapleau JP, Herschhorn A, Madani N, Princiotto A, Melillo B, Gu C, Zeng X, Mao Y, Smith AB 3rd, Sodroski J, Finzi A. Pacheco B, et al. Among authors: gu c. J Virol. 2017 Feb 14;91(5):e02219-16. doi: 10.1128/JVI.02219-16. Print 2017 Mar 1. J Virol. 2017. PMID: 28003492 Free PMC article.

5

Subunit organization of the membrane-bound HIV-1 envelope glycoprotein trimer.

Mao Y, Wang L, Gu C, Herschhorn A, Xiang SH, Haim H, Yang X, Sodroski J. Mao Y, et al. Among authors: gu c. Nat Struct Mol Biol. 2012 Sep;19(9):893-9. doi: 10.1038/nsmb.2351. Epub 2012 Aug 5. Nat Struct Mol Biol. 2012. PMID: 22864288 Free PMC article.

6

Molecular architecture of the uncleaved HIV-1 envelope glycoprotein trimer.

Mao Y, Wang L, Gu C, Herschhorn A, Désormeaux A, Finzi A, Xiang SH, Sodroski JG. Mao Y, et al. Among authors: gu c. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12438-43. doi: 10.1073/pnas.1307382110. Epub 2013 Jun 11. Proc Natl Acad Sci U S A. 2013. PMID: 23757493 Free PMC article.

7

Loss of a conserved N-linked glycosylation site in the simian immunodeficiency virus envelope glycoprotein V2 region enhances macrophage tropism by increasing CD4-independent cell-to-cell transmission.

Yen PJ, Herschhorn A, Haim H, Salas I, Gu C, Sodroski J, Gabuzda D. Yen PJ, et al. Among authors: gu c. J Virol. 2014 May;88(9):5014-28. doi: 10.1128/JVI.02785-13. Epub 2014 Feb 19. J Virol. 2014. PMID: 24554659 Free PMC article.

8

Comparative Analysis of the Glycosylation Profiles of Membrane-Anchored HIV-1 Envelope Glycoprotein Trimers and Soluble gp140.

Go EP, Herschhorn A, Gu C, Castillo-Menendez L, Zhang S, Mao Y, Chen H, Ding H, Wakefield JK, Hua D, Liao HX, Kappes JC, Sodroski J, Desaire H. Go EP, et al. Among authors: gu c. J Virol. 2015 Aug;89(16):8245-57. doi: 10.1128/JVI.00628-15. Epub 2015 May 27. J Virol. 2015. PMID: 26018173 Free PMC article.

9

Evaluation of the contribution of the transmembrane region to the ectodomain conformation of the human immunodeficiency virus (HIV-1) envelope glycoprotein.

Nguyen HT, Madani N, Ding H, Elder E, Princiotto A, Gu C, Darby P, Alin J, Herschhorn A, Kappes JC, Mao Y, Sodroski JG. Nguyen HT, et al. Among authors: gu c. Virol J. 2017 Feb 16;14(1):33. doi: 10.1186/s12985-017-0704-x. Virol J. 2017. PMID: 28209172 Free PMC article.

10

The β20-β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions.

Herschhorn A, Gu C, Moraca F, Ma X, Farrell M, Smith AB 3rd, Pancera M, Kwong PD, Schön A, Freire E, Abrams C, Blanchard SC, Mothes W, Sodroski JG. Herschhorn A, et al. Among authors: gu c. Nat Commun. 2017 Oct 19;8(1):1049. doi: 10.1038/s41467-017-01119-w. Nat Commun. 2017. PMID: 29051495 Free PMC article.

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