McMartin KE - Search Results

1

Oral Reference Dose for ethylene glycol based on oxalate crystal-induced renal tubule degeneration as the critical effect.

Snellings WM, Corley RA, McMartin KE, Kirman CR, Bobst SM. Snellings WM, et al. Among authors: mcmartin ke. Regul Toxicol Pharmacol. 2013 Mar;65(2):229-41. doi: 10.1016/j.yrtph.2012.12.005. Epub 2012 Dec 22. Regul Toxicol Pharmacol. 2013. PMID: 23266425

2

Dosimetry considerations in the enhanced sensitivity of male Wistar rats to chronic ethylene glycol-induced nephrotoxicity.

Corley RA, Wilson DM, Hard GC, Stebbins KE, Bartels MJ, Soelberg JJ, Dryzga MD, Gingell R, McMartin KE, Snellings WM. Corley RA, et al. Among authors: mcmartin ke. Toxicol Appl Pharmacol. 2008 Apr 15;228(2):165-78. doi: 10.1016/j.taap.2007.11.024. Epub 2007 Dec 4. Toxicol Appl Pharmacol. 2008. PMID: 18191429

3

Human health assessment for long-term oral ingestion of diethylene glycol.

Snellings WM, McMartin KE, Banton MI, Reitman F, Klapacz J. Snellings WM, et al. Among authors: mcmartin ke. Regul Toxicol Pharmacol. 2017 Jun 30;87 Suppl 2:S1-S20. doi: 10.1016/j.yrtph.2017.03.027. Epub 2017 Apr 29. Regul Toxicol Pharmacol. 2017. PMID: 28465071 Free article. Review.

4

Incorporation of therapeutic interventions in physiologically based pharmacokinetic modeling of human clinical case reports of accidental or intentional overdosing with ethylene glycol.

Corley RA, McMartin KE. Corley RA, et al. Among authors: mcmartin ke. Toxicol Sci. 2005 May;85(1):491-501. doi: 10.1093/toxsci/kfi120. Epub 2005 Feb 16. Toxicol Sci. 2005. PMID: 15716481

5

Extension of a PBPK model for ethylene glycol and glycolic acid to include the competitive formation and clearance of metabolites associated with kidney toxicity in rats and humans.

Corley RA, Saghir SA, Bartels MJ, Hansen SC, Creim J, McMartin KE, Snellings WM. Corley RA, et al. Among authors: mcmartin ke. Toxicol Appl Pharmacol. 2011 Feb 1;250(3):229-44. doi: 10.1016/j.taap.2010.10.011. Epub 2010 Nov 11. Toxicol Appl Pharmacol. 2011. PMID: 21074520

6

Subchronic toxicity of ethylene glycol in Wistar and F-344 rats related to metabolism and clearance of metabolites.

Cruzan G, Corley RA, Hard GC, Mertens JJ, McMartin KE, Snellings WM, Gingell R, Deyo JA. Cruzan G, et al. Among authors: mcmartin ke. Toxicol Sci. 2004 Oct;81(2):502-11. doi: 10.1093/toxsci/kfh206. Epub 2004 Jun 30. Toxicol Sci. 2004. PMID: 15229367

7

Renal toxicity of ethylene glycol results from internalization of calcium oxalate crystals by proximal tubule cells.

Hovda KE, Guo C, Austin R, McMartin KE. Hovda KE, et al. Among authors: mcmartin ke. Toxicol Lett. 2010 Feb 15;192(3):365-72. doi: 10.1016/j.toxlet.2009.11.013. Epub 2009 Nov 18. Toxicol Lett. 2010. PMID: 19931368

8

Calcium oxalate, and not other metabolites, is responsible for the renal toxicity of ethylene glycol.

Guo C, Cenac TA, Li Y, McMartin KE. Guo C, et al. Among authors: mcmartin ke. Toxicol Lett. 2007 Aug 30;173(1):8-16. doi: 10.1016/j.toxlet.2007.06.010. Epub 2007 Jun 20. Toxicol Lett. 2007. PMID: 17681674

9

Are calcium oxalate crystals involved in the mechanism of acute renal failure in ethylene glycol poisoning?

McMartin K. McMartin K. Clin Toxicol (Phila). 2009 Nov;47(9):859-69. doi: 10.3109/15563650903344793. Clin Toxicol (Phila). 2009. PMID: 19852621 Review.

10

The cytotoxicity of oxalate, metabolite of ethylene glycol, is due to calcium oxalate monohydrate formation.

Guo C, McMartin KE. Guo C, et al. Among authors: mcmartin ke. Toxicology. 2005 Mar 30;208(3):347-55. doi: 10.1016/j.tox.2004.11.029. Toxicology. 2005. PMID: 15695020

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