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Molecular pathways: microRNAs as cancer therapeutics.
Melo SA, Kalluri R. Melo SA, et al. Clin Cancer Res. 2012 Aug 15;18(16):4234-9. doi: 10.1158/1078-0432.CCR-11-2010. Epub 2012 Jun 18. Clin Cancer Res. 2012. PMID: 22711704 Free PMC article. Review.
Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer.
Kahlert C, Melo SA, Protopopov A, Tang J, Seth S, Koch M, Zhang J, Weitz J, Chin L, Futreal A, Kalluri R. Kahlert C, et al. Among authors: melo sa. J Biol Chem. 2014 Feb 14;289(7):3869-75. doi: 10.1074/jbc.C113.532267. Epub 2014 Jan 7. J Biol Chem. 2014. PMID: 24398677 Free PMC article. Clinical Trial.
Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis.
Melo SA, Sugimoto H, O'Connell JT, Kato N, Villanueva A, Vidal A, Qiu L, Vitkin E, Perelman LT, Melo CA, Lucci A, Ivan C, Calin GA, Kalluri R. Melo SA, et al. Among authors: melo ca. Cancer Cell. 2014 Nov 10;26(5):707-21. doi: 10.1016/j.ccell.2014.09.005. Epub 2014 Oct 23. Cancer Cell. 2014. PMID: 25446899 Free PMC article.
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer.
Melo SA, Luecke LB, Kahlert C, Fernandez AF, Gammon ST, Kaye J, LeBleu VS, Mittendorf EA, Weitz J, Rahbari N, Reissfelder C, Pilarsky C, Fraga MF, Piwnica-Worms D, Kalluri R. Melo SA, et al. Nature. 2015 Jul 9;523(7559):177-82. doi: 10.1038/nature14581. Epub 2015 Jun 24. Nature. 2015. PMID: 26106858 Free PMC article.
Detection of mutant KRAS and TP53 DNA in circulating exosomes from healthy individuals and patients with pancreatic cancer.
Yang S, Che SP, Kurywchak P, Tavormina JL, Gansmo LB, Correa de Sampaio P, Tachezy M, Bockhorn M, Gebauer F, Haltom AR, Melo SA, LeBleu VS, Kalluri R. Yang S, et al. Among authors: melo sa. Cancer Biol Ther. 2017 Mar 4;18(3):158-165. doi: 10.1080/15384047.2017.1281499. Epub 2017 Jan 25. Cancer Biol Ther. 2017. PMID: 28121262 Free PMC article.
77 results