Kjeldsen T - Search Results

1

Insulin analog with additional disulfide bond has increased stability and preserved activity.

Vinther TN, Norrman M, Ribel U, Huus K, Schlein M, Steensgaard DB, Pedersen TÅ, Pettersson I, Ludvigsen S, Kjeldsen T, Jensen KJ, Hubálek F. Vinther TN, et al. Among authors: kjeldsen t. Protein Sci. 2013 Mar;22(3):296-305. doi: 10.1002/pro.2211. Epub 2013 Jan 17. Protein Sci. 2013. PMID: 23281053 Free PMC article.

2

Interactions of a hybrid insulin/insulin-like growth factor-I analog with chimeric insulin/type I insulin-like growth factor receptors.

Schäffer L, Kjeldsen T, Andersen AS, Wiberg FC, Larsen UD, Cara JF, Mirmira RG, Nakagawa SH, Tager HS. Schäffer L, et al. Among authors: kjeldsen t. J Biol Chem. 1993 Feb 15;268(5):3044-7. J Biol Chem. 1993. PMID: 8428981 Free article.

3

Expression of insulin in yeast: the importance of molecular adaptation for secretion and conversion.

Kjeldsen T, Balschmidt P, Diers I, Hach M, Kaarsholm NC, Ludvigsen S. Kjeldsen T, et al. Biotechnol Genet Eng Rev. 2001;18:89-121. doi: 10.1080/02648725.2001.10648010. Biotechnol Genet Eng Rev. 2001. PMID: 11530700 Review. No abstract available.

4

Engineering-enhanced protein secretory expression in yeast with application to insulin.

Kjeldsen T, Ludvigsen S, Diers I, Balschmidt P, Sorensen AR, Kaarsholm NC. Kjeldsen T, et al. J Biol Chem. 2002 May 24;277(21):18245-8. doi: 10.1074/jbc.C200137200. Epub 2002 Mar 28. J Biol Chem. 2002. PMID: 11923277 Free article.

5

Importance of the solvent-exposed residues of the insulin B chain alpha-helix for receptor binding.

Glendorf T, Sørensen AR, Nishimura E, Pettersson I, Kjeldsen T. Glendorf T, et al. Among authors: kjeldsen t. Biochemistry. 2008 Apr 22;47(16):4743-51. doi: 10.1021/bi800054z. Epub 2008 Apr 1. Biochemistry. 2008. PMID: 18376848

6

Engineering of insulin receptor isoform-selective insulin analogues.

Glendorf T, Stidsen CE, Norrman M, Nishimura E, Sørensen AR, Kjeldsen T. Glendorf T, et al. Among authors: kjeldsen t. PLoS One. 2011;6(5):e20288. doi: 10.1371/journal.pone.0020288. Epub 2011 May 20. PLoS One. 2011. PMID: 21625452 Free PMC article.

7

Receptor-isoform-selective insulin analogues give tissue-preferential effects.

Vienberg SG, Bouman SD, Sørensen H, Stidsen CE, Kjeldsen T, Glendorf T, Sørensen AR, Olsen GS, Andersen B, Nishimura E. Vienberg SG, et al. Among authors: kjeldsen t. Biochem J. 2011 Dec 15;440(3):301-8. doi: 10.1042/BJ20110880. Biochem J. 2011. PMID: 21851336

8

Identification of anchor points for chemical modification of a small cysteine-rich protein by using a cysteine scan.

Vinther TN, Ribel U, Pedersen TA, Kjeldsen TB, Jensen KJ, Hubálek F. Vinther TN, et al. Chembiochem. 2011 Nov 4;12(16):2448-55. doi: 10.1002/cbic.201100464. Epub 2011 Sep 8. Chembiochem. 2011. PMID: 21905194

9

Novel covalently linked insulin dimer engineered to investigate the function of insulin dimerization.

Vinther TN, Norrman M, Strauss HM, Huus K, Schlein M, Pedersen TÅ, Kjeldsen T, Jensen KJ, Hubálek F. Vinther TN, et al. Among authors: kjeldsen t. PLoS One. 2012;7(2):e30882. doi: 10.1371/journal.pone.0030882. Epub 2012 Feb 17. PLoS One. 2012. PMID: 22363506 Free PMC article.

10

Systematic evaluation of the metabolic to mitogenic potency ratio for B10-substituted insulin analogues.

Glendorf T, Knudsen L, Stidsen CE, Hansen BF, Hegelund AC, Sørensen AR, Nishimura E, Kjeldsen T. Glendorf T, et al. Among authors: kjeldsen t. PLoS One. 2012;7(2):e29198. doi: 10.1371/journal.pone.0029198. Epub 2012 Feb 22. PLoS One. 2012. PMID: 22383948 Free PMC article.

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