Skoultchi A - Search Results

1

High resolution methylome analysis reveals widespread functional hypomethylation during adult human erythropoiesis.

Yu Y, Mo Y, Ebenezer D, Bhattacharyya S, Liu H, Sundaravel S, Giricz O, Wontakal S, Cartier J, Caces B, Artz A, Nischal S, Bhagat T, Bathon K, Maqbool S, Gligich O, Suzuki M, Steidl U, Godley L, Skoultchi A, Greally J, Wickrema A, Verma A. Yu Y, et al. Among authors: skoultchi a. J Biol Chem. 2013 Mar 29;288(13):8805-14. doi: 10.1074/jbc.M112.423756. Epub 2013 Jan 10. J Biol Chem. 2013. PMID: 23306203 Free PMC article.

2

PU.1 directly regulates cdk6 gene expression, linking the cell proliferation and differentiation programs in erythroid cells.

Choe KS, Ujhelly O, Wontakal SN, Skoultchi AI. Choe KS, et al. J Biol Chem. 2010 Jan 29;285(5):3044-52. doi: 10.1074/jbc.M109.077727. Epub 2009 Dec 2. J Biol Chem. 2010. PMID: 19955566 Free PMC article.

3

GATA-1 directly regulates p21 gene expression during erythroid differentiation.

Papetti M, Wontakal SN, Stopka T, Skoultchi AI. Papetti M, et al. Cell Cycle. 2010 May 15;9(10):1972-80. doi: 10.4161/cc.9.10.11602. Epub 2010 May 15. Cell Cycle. 2010. PMID: 20495378 Free PMC article.

4

A large gene network in immature erythroid cells is controlled by the myeloid and B cell transcriptional regulator PU.1.

Wontakal SN, Guo X, Will B, Shi M, Raha D, Mahajan MC, Weissman S, Snyder M, Steidl U, Zheng D, Skoultchi AI. Wontakal SN, et al. PLoS Genet. 2011 Jun;7(6):e1001392. doi: 10.1371/journal.pgen.1001392. Epub 2011 Jun 9. PLoS Genet. 2011. PMID: 21695229 Free PMC article.

5

A core erythroid transcriptional network is repressed by a master regulator of myelo-lymphoid differentiation.

Wontakal SN, Guo X, Smith C, MacCarthy T, Bresnick EH, Bergman A, Snyder MP, Weissman SM, Zheng D, Skoultchi AI. Wontakal SN, et al. Among authors: skoultchi ai. Proc Natl Acad Sci U S A. 2012 Mar 6;109(10):3832-7. doi: 10.1073/pnas.1121019109. Epub 2012 Feb 22. Proc Natl Acad Sci U S A. 2012. PMID: 22357756 Free PMC article.

6

Runx1 promotes murine erythroid progenitor proliferation and inhibits differentiation by preventing Pu.1 downregulation.

Willcockson MA, Taylor SJ, Ghosh S, Healton SE, Wheat JC, Wilson TJ, Steidl U, Skoultchi AI. Willcockson MA, et al. Among authors: skoultchi ai. Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):17841-17847. doi: 10.1073/pnas.1901122116. Epub 2019 Aug 20. Proc Natl Acad Sci U S A. 2019. PMID: 31431533 Free PMC article.

7

Linker histone H1 is essential for Drosophila development, the establishment of pericentric heterochromatin, and a normal polytene chromosome structure.

Lu X, Wontakal SN, Emelyanov AV, Morcillo P, Konev AY, Fyodorov DV, Skoultchi AI. Lu X, et al. Genes Dev. 2009 Feb 15;23(4):452-65. doi: 10.1101/gad.1749309. Epub 2009 Feb 4. Genes Dev. 2009. PMID: 19196654 Free PMC article.

8

Transcriptional burst fraction and size dynamics during lens fiber cell differentiation and detailed insights into the denucleation process.

Limi S, Senecal A, Coleman R, Lopez-Jones M, Guo P, Polumbo C, Singer RH, Skoultchi AI, Cvekl A. Limi S, et al. Among authors: skoultchi ai. J Biol Chem. 2018 Aug 24;293(34):13176-13190. doi: 10.1074/jbc.RA118.001927. Epub 2018 Jun 29. J Biol Chem. 2018. PMID: 29959226 Free PMC article.

9

Single-molecule imaging of transcription dynamics in somatic stem cells.

Wheat JC, Sella Y, Willcockson M, Skoultchi AI, Bergman A, Singer RH, Steidl U. Wheat JC, et al. Among authors: skoultchi ai. Nature. 2020 Jul;583(7816):431-436. doi: 10.1038/s41586-020-2432-4. Epub 2020 Jun 24. Nature. 2020. PMID: 32581360 Free PMC article.

10

Reductions in linker histone levels are tolerated in developing spermatocytes but cause changes in specific gene expression.

Lin Q, Inselman A, Han X, Xu H, Zhang W, Handel MA, Skoultchi AI. Lin Q, et al. Among authors: skoultchi ai. J Biol Chem. 2004 May 28;279(22):23525-35. doi: 10.1074/jbc.M400925200. Epub 2004 Mar 23. J Biol Chem. 2004. PMID: 15039436 Free article.

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