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Metformin, at concentrations corresponding to the treatment of diabetes, potentiates the cytotoxic effects of carboplatin in cultures of ovarian cancer cells.
Erices R, Bravo ML, Gonzalez P, Oliva B, Racordon D, Garrido M, Ibañez C, Kato S, Brañes J, Pizarro J, Barriga MI, Barra A, Bravo E, Alonso C, Bustamente E, Cuello MA, Owen GI. Erices R, et al. Among authors: owen gi. Reprod Sci. 2013 Dec;20(12):1433-46. doi: 10.1177/1933719113488441. Epub 2013 May 7. Reprod Sci. 2013. PMID: 23653391 Free PMC article.
Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian cancer cells.
Orellana R, Kato S, Erices R, Bravo ML, Gonzalez P, Oliva B, Cubillos S, Valdivia A, Ibañez C, Brañes J, Barriga MI, Bravo E, Alonso C, Bustamente E, Castellon E, Hidalgo P, Trigo C, Panes O, Pereira J, Mezzano D, Cuello MA, Owen GI. Orellana R, et al. Among authors: owen gi. BMC Cancer. 2015 Apr 15;15:290. doi: 10.1186/s12885-015-1304-z. BMC Cancer. 2015. PMID: 25886038 Free PMC article.
Diabetic concentrations of metformin inhibit platelet-mediated ovarian cancer cell progression.
Erices R, Cubillos S, Aravena R, Santoro F, Marquez M, Orellana R, Ramírez C, González P, Fuenzalida P, Bravo ML, Oliva B, Kato S, Ibañez C, Brañes J, Bravo E, Alonso C, García K, Arab C, Torres VA, Godoy AS, Pereira J, Bustos G, Cardenas JC, Cuello MA, Owen GI. Erices R, et al. Among authors: owen gi. Oncotarget. 2017 Mar 28;8(13):20865-20880. doi: 10.18632/oncotarget.15348. Oncotarget. 2017. PMID: 28209916 Free PMC article.
Structural and functional identification of vasculogenic mimicry in vitro.
Racordon D, Valdivia A, Mingo G, Erices R, Aravena R, Santoro F, Bravo ML, Ramirez C, Gonzalez P, Sandoval A, González A, Retamal C, Kogan MJ, Kato S, Cuello MA, Osorio G, Nualart F, Alvares P, Gago-Arias A, Fabri D, Espinoza I, Sanchez B, Corvalán AH, Pinto MP, Owen GI. Racordon D, et al. Among authors: owen gi. Sci Rep. 2017 Aug 1;7(1):6985. doi: 10.1038/s41598-017-07622-w. Sci Rep. 2017. PMID: 28765613 Free PMC article.
MicroRNA-335-5p is a potential suppressor of metastasis and invasion in gastric cancer.
Sandoval-Bórquez A, Polakovicova I, Carrasco-Véliz N, Lobos-González L, Riquelme I, Carrasco-Avino G, Bizama C, Norero E, Owen GI, Roa JC, Corvalán AH. Sandoval-Bórquez A, et al. Among authors: owen gi. Clin Epigenetics. 2017 Oct 17;9:114. doi: 10.1186/s13148-017-0413-8. eCollection 2017. Clin Epigenetics. 2017. PMID: 29075357 Free PMC article.
LEPTIN PROMOTES A MORE AGGRESIVE BEHAVIOR OF OVARIAN CANCER CELLS: A POTENTIAL EXPLANATION FOR A WORSE PROGNOSIS IN OBESE OVARIAN CANCER PATIENTS: IGCS-0095 Ovarian Cancer.
Cuello-Fredes M, Kato S, Abarzúa-Catalán L, Delpiano A, Trigo C, García K, Sanhueza C, Ibañez C, Brañes J, Castellon E, Owen G. Cuello-Fredes M, et al. Int J Gynecol Cancer. 2015 May;25 Suppl 1:67. doi: 10.1097/00009577-201505001-00052. Int J Gynecol Cancer. 2015. PMID: 25955943 No abstract available.
95 results