Koumenis C - Search Results

1

PERK-ing up autophagy during MYC-induced tumorigenesis.

Dey S, Tameire F, Koumenis C. Dey S, et al. Among authors: koumenis c. Autophagy. 2013 Apr;9(4):612-4. doi: 10.4161/auto.23486. Epub 2013 Jan 17. Autophagy. 2013. PMID: 23328692 Free PMC article.

2

The PERK/eIF2alpha/ATF4 module of the UPR in hypoxia resistance and tumor growth.

Fels DR, Koumenis C. Fels DR, et al. Among authors: koumenis c. Cancer Biol Ther. 2006 Jul;5(7):723-8. doi: 10.4161/cbt.5.7.2967. Epub 2006 Jul 1. Cancer Biol Ther. 2006. PMID: 16861899 Free article. Review.

3

Preferential cytotoxicity of bortezomib toward hypoxic tumor cells via overactivation of endoplasmic reticulum stress pathways.

Fels DR, Ye J, Segan AT, Kridel SJ, Spiotto M, Olson M, Koong AC, Koumenis C. Fels DR, et al. Among authors: koumenis c. Cancer Res. 2008 Nov 15;68(22):9323-30. doi: 10.1158/0008-5472.CAN-08-2873. Cancer Res. 2008. PMID: 19010906 Free PMC article.

4

ATF4, an ER stress and hypoxia-inducible transcription factor and its potential role in hypoxia tolerance and tumorigenesis.

Ye J, Koumenis C. Ye J, et al. Among authors: koumenis c. Curr Mol Med. 2009 May;9(4):411-6. doi: 10.2174/156652409788167096. Curr Mol Med. 2009. PMID: 19519398 Review.

5

Location, location, location-makes all the difference for hypoxia in lung tumors.

Maity A, Koumenis C. Maity A, et al. Among authors: koumenis c. Clin Cancer Res. 2010 Oct 1;16(19):4685-7. doi: 10.1158/1078-0432.CCR-10-2004. Epub 2010 Sep 21. Clin Cancer Res. 2010. PMID: 20858842 Free PMC article.

6

miR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner.

Chitnis NS, Pytel D, Bobrovnikova-Marjon E, Pant D, Zheng H, Maas NL, Frederick B, Kushner JA, Chodosh LA, Koumenis C, Fuchs SY, Diehl JA. Chitnis NS, et al. Among authors: koumenis c. Mol Cell. 2012 Nov 9;48(3):353-64. doi: 10.1016/j.molcel.2012.08.025. Epub 2012 Sep 27. Mol Cell. 2012. PMID: 23022383 Free PMC article.

7

ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth.

Hart LS, Cunningham JT, Datta T, Dey S, Tameire F, Lehman SL, Qiu B, Zhang H, Cerniglia G, Bi M, Li Y, Gao Y, Liu H, Li C, Maity A, Thomas-Tikhonenko A, Perl AE, Koong A, Fuchs SY, Diehl JA, Mills IG, Ruggero D, Koumenis C. Hart LS, et al. Among authors: koumenis c. J Clin Invest. 2012 Dec;122(12):4621-34. doi: 10.1172/JCI62973. Epub 2012 Nov 12. J Clin Invest. 2012. PMID: 23143306 Free PMC article.

8

Identification and characterization of a potent activator of p53-independent cellular senescence via a small-molecule screen for modifiers of the integrated stress response.

Sayers CM, Papandreou I, Guttmann DM, Maas NL, Diehl JA, Witze ES, Koong AC, Koumenis C. Sayers CM, et al. Among authors: koumenis c. Mol Pharmacol. 2013 Mar;83(3):594-604. doi: 10.1124/mol.112.081810. Epub 2012 Dec 10. Mol Pharmacol. 2013. PMID: 23229510 Free PMC article.

9

Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma.

Ma XH, Piao SF, Dey S, McAfee Q, Karakousis G, Villanueva J, Hart LS, Levi S, Hu J, Zhang G, Lazova R, Klump V, Pawelek JM, Xu X, Xu W, Schuchter LM, Davies MA, Herlyn M, Winkler J, Koumenis C, Amaravadi RK. Ma XH, et al. Among authors: koumenis c. J Clin Invest. 2014 Mar;124(3):1406-17. doi: 10.1172/JCI70454. Epub 2014 Feb 24. J Clin Invest. 2014. PMID: 24569374 Free PMC article.

10

Cell intrinsic and extrinsic activators of the unfolded protein response in cancer: Mechanisms and targets for therapy.

Tameire F, Verginadis II, Koumenis C. Tameire F, et al. Among authors: koumenis c. Semin Cancer Biol. 2015 Aug;33:3-15. doi: 10.1016/j.semcancer.2015.04.002. Epub 2015 Apr 25. Semin Cancer Biol. 2015. PMID: 25920797 Free PMC article. Review.

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