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Page 1
Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism.
Pieretti S, Haanstra JR, Mazet M, Perozzo R, Bergamini C, Prati F, Fato R, Lenaz G, Capranico G, Brun R, Bakker BM, Michels PA, Scapozza L, Bolognesi ML, Cavalli A. Pieretti S, et al. Among authors: mazet m. PLoS Negl Trop Dis. 2013;7(1):e2012. doi: 10.1371/journal.pntd.0002012. Epub 2013 Jan 17. PLoS Negl Trop Dis. 2013. PMID: 23350008 Free PMC article.
Cytosolic NADPH homeostasis in glucose-starved procyclic Trypanosoma brucei relies on malic enzyme and the pentose phosphate pathway fed by gluconeogenic flux.
Allmann S, Morand P, Ebikeme C, Gales L, Biran M, Hubert J, Brennand A, Mazet M, Franconi JM, Michels PA, Portais JC, Boshart M, Bringaud F. Allmann S, et al. Among authors: mazet m. J Biol Chem. 2013 Jun 21;288(25):18494-505. doi: 10.1074/jbc.M113.462978. Epub 2013 May 10. J Biol Chem. 2013. PMID: 23665470 Free PMC article.
Probing the metabolic network in bloodstream-form Trypanosoma brucei using untargeted metabolomics with stable isotope labelled glucose.
Creek DJ, Mazet M, Achcar F, Anderson J, Kim DH, Kamour R, Morand P, Millerioux Y, Biran M, Kerkhoven EJ, Chokkathukalam A, Weidt SK, Burgess KE, Breitling R, Watson DG, Bringaud F, Barrett MP. Creek DJ, et al. Among authors: mazet m. PLoS Pathog. 2015 Mar 16;11(3):e1004689. doi: 10.1371/journal.ppat.1004689. eCollection 2015 Mar. PLoS Pathog. 2015. PMID: 25775470 Free PMC article.
Revisiting the central metabolism of the bloodstream forms of Trypanosoma brucei: production of acetate in the mitochondrion is essential for parasite viability.
Mazet M, Morand P, Biran M, Bouyssou G, Courtois P, Daulouède S, Millerioux Y, Franconi JM, Vincendeau P, Moreau P, Bringaud F. Mazet M, et al. PLoS Negl Trop Dis. 2013 Dec 19;7(12):e2587. doi: 10.1371/journal.pntd.0002587. eCollection 2013. PLoS Negl Trop Dis. 2013. PMID: 24367711 Free PMC article.
ATP synthesis-coupled and -uncoupled acetate production from acetyl-CoA by mitochondrial acetate:succinate CoA-transferase and acetyl-CoA thioesterase in Trypanosoma.
Millerioux Y, Morand P, Biran M, Mazet M, Moreau P, Wargnies M, Ebikeme C, Deramchia K, Gales L, Portais JC, Boshart M, Franconi JM, Bringaud F. Millerioux Y, et al. Among authors: mazet m. J Biol Chem. 2012 May 18;287(21):17186-17197. doi: 10.1074/jbc.M112.355404. Epub 2012 Apr 2. J Biol Chem. 2012. PMID: 22474284 Free PMC article.
The threonine degradation pathway of the Trypanosoma brucei procyclic form: the main carbon source for lipid biosynthesis is under metabolic control.
Millerioux Y, Ebikeme C, Biran M, Morand P, Bouyssou G, Vincent IM, Mazet M, Riviere L, Franconi JM, Burchmore RJ, Moreau P, Barrett MP, Bringaud F. Millerioux Y, et al. Among authors: mazet m. Mol Microbiol. 2013 Oct;90(1):114-29. doi: 10.1111/mmi.12351. Epub 2013 Aug 25. Mol Microbiol. 2013. PMID: 23899193 Free PMC article.
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