Li JG - Search Results

1

The influence of 5-lipoxygenase on Alzheimer's disease-related tau pathology: in vivo and in vitro evidence.

Chu J, Li JG, Ceballos-Diaz C, Golde T, Praticò D. Chu J, et al. Among authors: li jg. Biol Psychiatry. 2013 Sep 1;74(5):321-8. doi: 10.1016/j.biopsych.2012.12.012. Epub 2013 Jan 23. Biol Psychiatry. 2013. PMID: 23352590 Free PMC article.

2

Homocysteine exacerbates β-amyloid pathology, tau pathology, and cognitive deficit in a mouse model of Alzheimer disease with plaques and tangles.

Li JG, Chu J, Barrero C, Merali S, Praticò D. Li JG, et al. Ann Neurol. 2014 Jun;75(6):851-63. doi: 10.1002/ana.24145. Epub 2014 May 28. Ann Neurol. 2014. PMID: 24644038 Free PMC article.

3

Gamma secretase-activating protein is a substrate for caspase-3: implications for Alzheimer's disease.

Chu J, Li JG, Joshi YB, Giannopoulos PF, Hoffman NE, Madesh M, Praticò D. Chu J, et al. Among authors: li jg. Biol Psychiatry. 2015 Apr 15;77(8):720-8. doi: 10.1016/j.biopsych.2014.06.003. Epub 2014 Jun 16. Biol Psychiatry. 2015. PMID: 25052851 Free PMC article.

4

High levels of homocysteine results in cerebral amyloid angiopathy in mice.

Li JG, Praticò D. Li JG, et al. J Alzheimers Dis. 2015;43(1):29-35. doi: 10.3233/JAD-141101. J Alzheimers Dis. 2015. PMID: 25061050 Free PMC article.

5

Degradation of gamma secretase activating protein by the ubiquitin-proteasome pathway.

Chu J, Li JG, Hoffman NE, Madesh M, Praticò D. Chu J, et al. Among authors: li jg. J Neurochem. 2015 May;133(3):432-9. doi: 10.1111/jnc.13011. Epub 2015 Feb 13. J Neurochem. 2015. PMID: 25533523 Free PMC article.

6

Pharmacologic inhibition of 5-lipoxygenase improves memory, rescues synaptic dysfunction, and ameliorates tau pathology in a transgenic model of tauopathy.

Giannopoulos PF, Chu J, Sperow M, Li JG, Yu WH, Kirby LG, Abood M, Praticò D. Giannopoulos PF, et al. Among authors: li jg. Biol Psychiatry. 2015 Nov 15;78(10):693-701. doi: 10.1016/j.biopsych.2015.01.015. Epub 2015 Feb 7. Biol Psychiatry. 2015. Retraction in: Biol Psychiatry. 2024 Jul 15;96(2):160. doi: 10.1016/j.biopsych.2024.05.002 PMID: 25802082 Free PMC article. Retracted.

7

Regulation of gamma-secretase activating protein by the 5Lipoxygenase: in vitro and in vivo evidence.

Chu J, Li JG, Hoffman NE, Stough AM, Madesh M, Praticò D. Chu J, et al. Among authors: li jg. Sci Rep. 2015 Jun 16;5:11086. doi: 10.1038/srep11086. Sci Rep. 2015. PMID: 26076991 Free PMC article.

8

12/15-Lipoxygenase Inhibition Reverses Cognitive Impairment, Brain Amyloidosis, and Tau Pathology by Stimulating Autophagy in Aged Triple Transgenic Mice.

Di Meco A, Li JG, Blass BE, Abou-Gharbia M, Lauretti E, Praticò D. Di Meco A, et al. Among authors: li jg. Biol Psychiatry. 2017 Jan 15;81(2):92-100. doi: 10.1016/j.biopsych.2016.05.023. Epub 2016 Jun 4. Biol Psychiatry. 2017. PMID: 27499089

9

Homocysteine modulates 5-lipoxygenase expression level via DNA methylation.

Li JG, Barrero C, Gupta S, Kruger WD, Merali S, Praticò D. Li JG, et al. Aging Cell. 2017 Apr;16(2):273-280. doi: 10.1111/acel.12550. Epub 2016 Nov 29. Aging Cell. 2017. PMID: 27896923 Free PMC article.

10

Genetic absence of ALOX5 protects from homocysteine-induced memory impairment, tau phosphorylation and synaptic pathology.

Li JG, Barrero C, Merali S, Praticò D. Li JG, et al. Hum Mol Genet. 2017 May 15;26(10):1855-1862. doi: 10.1093/hmg/ddx088. Hum Mol Genet. 2017. PMID: 28334897 Free PMC article.

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