Berthoux L - Search Results

1

A novel aminoacid determinant of HIV-1 restriction in the TRIM5α variable 1 region isolated in a random mutagenic screen.

Pham QT, Veillette M, Brandariz-Nuñez A, Pawlica P, Thibert-Lefebvre C, Chandonnet N, Diaz-Griffero F, Berthoux L. Pham QT, et al. Among authors: berthoux l. Virus Res. 2013 May;173(2):306-314. doi: 10.1016/j.virusres.2013.01.013. Epub 2013 Jan 25. Virus Res. 2013. PMID: 23357295 Free PMC article.

2

Generation of human TRIM5alpha mutants with high HIV-1 restriction activity.

Pham QT, Bouchard A, Grütter MG, Berthoux L. Pham QT, et al. Among authors: berthoux l. Gene Ther. 2010 Jul;17(7):859-71. doi: 10.1038/gt.2010.40. Epub 2010 Apr 1. Gene Ther. 2010. PMID: 20357830

3

Murine double minute 2 as a modulator of retroviral restrictions mediated by TRIM5alpha.

Malbec M, Pham QT, Plourde MB, Létourneau-Hogan A, Nepveu-Traversy ME, Berthoux L. Malbec M, et al. Among authors: berthoux l. Virology. 2010 Sep 30;405(2):414-23. doi: 10.1016/j.virol.2010.06.021. Epub 2010 Jul 8. Virology. 2010. PMID: 20619429 Free article.

4

The V86M mutation in HIV-1 capsid confers resistance to TRIM5α by abrogation of cyclophilin A-dependent restriction and enhancement of viral nuclear import.

Veillette M, Bichel K, Pawlica P, Freund SM, Plourde MB, Pham QT, Reyes-Moreno C, James LC, Berthoux L. Veillette M, et al. Among authors: berthoux l. Retrovirology. 2013 Feb 28;10:25. doi: 10.1186/1742-4690-10-25. Retrovirology. 2013. PMID: 23448277 Free PMC article.

5

The conserved sumoylation consensus site in TRIM5α modulates its immune activation functions.

Nepveu-Traversy MÉ, Berthoux L. Nepveu-Traversy MÉ, et al. Among authors: berthoux l. Virus Res. 2014 May 12;184:30-8. doi: 10.1016/j.virusres.2014.02.013. Epub 2014 Feb 25. Virus Res. 2014. PMID: 24583231

6

Functional evidence for the involvement of microtubules and dynein motor complexes in TRIM5α-mediated restriction of retroviruses.

Pawlica P, Le Sage V, Poccardi N, Tremblay MJ, Mouland AJ, Berthoux L. Pawlica P, et al. Among authors: berthoux l. J Virol. 2014 May;88(10):5661-76. doi: 10.1128/JVI.03717-13. Epub 2014 Mar 5. J Virol. 2014. PMID: 24600008 Free PMC article.

7

Cytoplasmic dynein promotes HIV-1 uncoating.

Pawlica P, Berthoux L. Pawlica P, et al. Among authors: berthoux l. Viruses. 2014 Nov 4;6(11):4195-211. doi: 10.3390/v6114195. Viruses. 2014. PMID: 25375884 Free PMC article.

8

Inhibition of microtubules and dynein rescues human immunodeficiency virus type 1 from owl monkey TRIMCyp-mediated restriction in a cellular context-specific fashion.

Pawlica P, Dufour C, Berthoux L. Pawlica P, et al. Among authors: berthoux l. J Gen Virol. 2015 Apr;96(Pt 4):874-886. doi: 10.1099/jgv.0.000018. Epub 2014 Dec 12. J Gen Virol. 2015. PMID: 25502651

9

Restriction Factors in HIV-1 Disease Progression.

Merindol N, Berthoux L. Merindol N, et al. Among authors: berthoux l. Curr HIV Res. 2015;13(6):448-61. doi: 10.2174/1570162x13666150608104412. Curr HIV Res. 2015. PMID: 26051387 Review.

10

Preclinical Assessment of Mutant Human TRIM5α as an Anti-HIV-1 Transgene.

Jung U, Urak K, Veillette M, Nepveu-Traversy MÉ, Pham QT, Hamel S, Rossi JJ, Berthoux L. Jung U, et al. Among authors: berthoux l. Hum Gene Ther. 2015 Oct;26(10):664-79. doi: 10.1089/hum.2015.059. Epub 2015 Aug 6. Hum Gene Ther. 2015. PMID: 26076730 Free PMC article.

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