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Page 1
Characterization of a novel CRAC inhibitor that potently blocks human T cell activation and effector functions.
Chen G, Panicker S, Lau KY, Apparsundaram S, Patel VA, Chen SL, Soto R, Jung JK, Ravindran P, Okuhara D, Bohnert G, Che Q, Rao PE, Allard JD, Badi L, Bitter HM, Nunn PA, Narula SK, DeMartino JA. Chen G, et al. Among authors: okuhara d. Mol Immunol. 2013 Jul;54(3-4):355-67. doi: 10.1016/j.molimm.2012.12.011. Epub 2013 Jan 26. Mol Immunol. 2013. PMID: 23357789
Transient receptor potential channels as drug targets.
Okuhara DY, Hsia AY, Xie M. Okuhara DY, et al. Expert Opin Ther Targets. 2007 Mar;11(3):391-401. doi: 10.1517/14728222.11.3.391. Expert Opin Ther Targets. 2007. PMID: 17298296 Review.
A two-dose viral-vectored Plasmodium vivax multistage vaccine confers durable protection and transmission-blockade in a pre-clinical study.
Yamamoto Y, Fabbri C, Okuhara D, Takagi R, Kawabata Y, Katayama T, Iyori M, Hasyim AA, Sakamoto A, Mizukami H, Shida H, Lopes S, Yoshida S. Yamamoto Y, et al. Among authors: okuhara d. Front Immunol. 2024 Apr 30;15:1372584. doi: 10.3389/fimmu.2024.1372584. eCollection 2024. Front Immunol. 2024. PMID: 38745665 Free PMC article.
Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions.
Purdue MP, Dutta D, Machiela MJ, Gorman BR, Winter T, Okuhara D, Cleland S, Ferreiro-Iglesias A, Scheet P, Liu A, Wu C, Antwi SO, Larkin J, Zequi SC, Sun M, Hikino K, Hajiran A, Lawson KA, Cárcano F, Blanchet O, Shuch B, Nepple KG, Margue G, Sundi D, Diver WR, Folgueira MAAK, van Bokhoven A, Neffa F, Brown KM, Hofmann JN, Rhee J, Yeager M, Cole NR, Hicks BD, Manning MR, Hutchinson AA, Rothman N, Huang WY, Linehan WM, Lori A, Ferragu M, Zidane-Marinnes M, Serrano SV, Magnabosco WJ; BioBank Japan Project; Vilas A, Decia R, Carusso F, Graham LS, Anderson K, Bilen MA, Arciero C, Pellegrin I, Ricard S; FinnGen; Scelo G, Banks RE, Vasudev NS, Soomro N, Stewart GD, Adeyoju A, Bromage S, Hrouda D, Gibbons N, Patel P, Sullivan M, Protheroe A, Nugent FI, Fournier MJ, Zhang X, Martin LJ, Komisarenko M, Eisen T, Cunningham SA, Connolly DC, Uzzo RG, Zaridze D, Mukeria A, Holcatova I, Hornakova A, Foretova L, Janout V, Mates D, Jinga V, Rascu S, Mijuskovic M, Savic S, Milosavljevic S, Gaborieau V, Abedi-Ardekani B, McKay J, Johansson M, Phouthavongsy L, Hayman L, Li J, Lungu I, Bezerra SM, Souza AG, Sares CTG, Reis RB, Gallucci FP, Cordeiro MD, Pomerantz M, Lee GM, Freedman ML, Jeong A, … See abstract for full author list ➔ Purdue MP, et al. Among authors: okuhara d. Nat Genet. 2024 May;56(5):809-818. doi: 10.1038/s41588-024-01725-7. Epub 2024 Apr 26. Nat Genet. 2024. PMID: 38671320
A new method for multiancestry polygenic prediction improves performance across diverse populations.
Zhang H, Zhan J, Jin J, Zhang J, Lu W, Zhao R, Ahearn TU, Yu Z, O'Connell J, Jiang Y, Chen T, Okuhara D; 23andMe Research Team; Garcia-Closas M, Lin X, Koelsch BL, Chatterjee N. Zhang H, et al. Among authors: okuhara d. Nat Genet. 2023 Oct;55(10):1757-1768. doi: 10.1038/s41588-023-01501-z. Epub 2023 Sep 25. Nat Genet. 2023. PMID: 37749244 Free PMC article.
Cofactor-enabled functional expression of fruit fly, honeybee, and bumblebee nicotinic receptors reveals picomolar neonicotinoid actions.
Ihara M, Furutani S, Shigetou S, Shimada S, Niki K, Komori Y, Kamiya M, Koizumi W, Magara L, Hikida M, Noguchi A, Okuhara D, Yoshinari Y, Kondo S, Tanimoto H, Niwa R, Sattelle DB, Matsuda K. Ihara M, et al. Among authors: okuhara d. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16283-16291. doi: 10.1073/pnas.2003667117. Epub 2020 Jul 1. Proc Natl Acad Sci U S A. 2020. PMID: 32611810 Free PMC article.
25 results