Checler F - Search Results

1

Parkin differently regulates presenilin-1 and presenilin-2 functions by direct control of their promoter transcription.

Duplan E, Sevalle J, Viotti J, Goiran T, Bauer C, Renbaum P, Levy-Lahad E, Gautier CA, Corti O, Leroudier N, Checler F, da Costa CA. Duplan E, et al. Among authors: checler f. J Mol Cell Biol. 2013 Apr;5(2):132-42. doi: 10.1093/jmcb/mjt003. Epub 2013 Jan 28. J Mol Cell Biol. 2013. PMID: 23359614

2

Alpha-secretase-derived product of beta-amyloid precursor protein is decreased by presenilin 1 mutations linked to familial Alzheimer's disease.

Ancolio K, Marambaud P, Dauch P, Checler F. Ancolio K, et al. Among authors: checler f. J Neurochem. 1997 Dec;69(6):2494-9. doi: 10.1046/j.1471-4159.1997.69062494.x. J Neurochem. 1997. PMID: 9375682 Free article.

3

Alzheimer's disease-linked mutation of presenilin 2 (N141I-PS2) drastically lowers APPalpha secretion: control by the proteasome.

Marambaud P, Alves da Costa C, Ancolio K, Checler F. Marambaud P, et al. Among authors: checler f. Biochem Biophys Res Commun. 1998 Nov 9;252(1):134-8. doi: 10.1006/bbrc.1998.9619. Biochem Biophys Res Commun. 1998. PMID: 9813158

4

C-terminal maturation fragments of presenilin 1 and 2 control secretion of APP alpha and A beta by human cells and are degraded by proteasome.

da Costa CA, Ancolio K, Checler F. da Costa CA, et al. Among authors: checler f. Mol Med. 1999 Mar;5(3):160-8. Mol Med. 1999. PMID: 10404513 Free PMC article.

5

Wild-type but not Parkinson's disease-related ala-53 --> Thr mutant alpha -synuclein protects neuronal cells from apoptotic stimuli.

da Costa CA, Ancolio K, Checler F. da Costa CA, et al. Among authors: checler f. J Biol Chem. 2000 Aug 4;275(31):24065-9. doi: 10.1074/jbc.M002413200. J Biol Chem. 2000. PMID: 10818098 Free article.

6

Role of the proteasome in Alzheimer's disease.

Checler F, da Costa CA, Ancolio K, Chevallier N, Lopez-Perez E, Marambaud P. Checler F, et al. Biochim Biophys Acta. 2000 Jul 26;1502(1):133-8. doi: 10.1016/s0925-4439(00)00039-9. Biochim Biophys Acta. 2000. PMID: 10899438 Free article. Review.

7

New protease inhibitors prevent gamma-secretase-mediated production of Abeta40/42 without affecting Notch cleavage.

Petit A, Bihel F, Alvès da Costa C, Pourquié O, Checler F, Kraus JL. Petit A, et al. Among authors: checler f. Nat Cell Biol. 2001 May;3(5):507-11. doi: 10.1038/35074581. Nat Cell Biol. 2001. PMID: 11331880

8

Endogenous beta-amyloid production in presenilin-deficient embryonic mouse fibroblasts.

Armogida M, Petit A, Vincent B, Scarzello S, da Costa CA, Checler F. Armogida M, et al. Among authors: checler f. Nat Cell Biol. 2001 Nov;3(11):1030-3. doi: 10.1038/ncb1101-1030. Nat Cell Biol. 2001. PMID: 11715026

9

Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons.

Alves da Costa C, Paitel E, Mattson MP, Amson R, Telerman A, Ancolio K, Checler F. Alves da Costa C, et al. Among authors: checler f. Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):4043-8. doi: 10.1073/pnas.062059899. Proc Natl Acad Sci U S A. 2002. PMID: 11904448 Free PMC article.

10

The C-terminal fragment of presenilin 2 triggers p53-mediated staurosporine-induced apoptosis, a function independent of the presenilinase-derived N-terminal counterpart.

Alves da Costa C, Mattson MP, Ancolio K, Checler F. Alves da Costa C, et al. Among authors: checler f. J Biol Chem. 2003 Apr 4;278(14):12064-9. doi: 10.1074/jbc.M212379200. Epub 2003 Jan 29. J Biol Chem. 2003. PMID: 12556443 Free article.

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