Smith SO - Search Results

1

Tryptophan at the transmembrane-cytosolic junction modulates thrombopoietin receptor dimerization and activation.

Defour JP, Itaya M, Gryshkova V, Brett IC, Pecquet C, Sato T, Smith SO, Constantinescu SN. Defour JP, et al. Among authors: smith so. Proc Natl Acad Sci U S A. 2013 Feb 12;110(7):2540-5. doi: 10.1073/pnas.1211560110. Epub 2013 Jan 28. Proc Natl Acad Sci U S A. 2013. PMID: 23359689 Free PMC article.

2

Activation of the erythropoietin receptor by the gp55-P viral envelope protein is determined by a single amino acid in its transmembrane domain.

Constantinescu SN, Liu X, Beyer W, Fallon A, Shekar S, Henis YI, Smith SO, Lodish HF. Constantinescu SN, et al. Among authors: smith so. EMBO J. 1999 Jun 15;18(12):3334-47. doi: 10.1093/emboj/18.12.3334. EMBO J. 1999. PMID: 10369674 Free PMC article.

3

Active and inactive orientations of the transmembrane and cytosolic domains of the erythropoietin receptor dimer.

Seubert N, Royer Y, Staerk J, Kubatzky KF, Moucadel V, Krishnakumar S, Smith SO, Constantinescu SN. Seubert N, et al. Among authors: smith so. Mol Cell. 2003 Nov;12(5):1239-50. doi: 10.1016/s1097-2765(03)00389-7. Mol Cell. 2003. PMID: 14636581 Free article.

4

Structural requirements of the extracellular to transmembrane domain junction for erythropoietin receptor function.

Kubatzky KF, Liu W, Goldgraben K, Simmerling C, Smith SO, Constantinescu SN. Kubatzky KF, et al. Among authors: smith so. J Biol Chem. 2005 Apr 15;280(15):14844-54. doi: 10.1074/jbc.M411251200. Epub 2005 Jan 18. J Biol Chem. 2005. PMID: 15657048 Free article.

5

Helix packing and orientation in the transmembrane dimer of gp55-P of the spleen focus forming virus.

Liu W, Crocker E, Constantinescu SN, Smith SO. Liu W, et al. Among authors: smith so. Biophys J. 2005 Aug;89(2):1194-202. doi: 10.1529/biophysj.104.057844. Epub 2005 May 13. Biophys J. 2005. PMID: 15894629 Free PMC article.

6

An amphipathic motif at the transmembrane-cytoplasmic junction prevents autonomous activation of the thrombopoietin receptor.

Staerk J, Lacout C, Sato T, Smith SO, Vainchenker W, Constantinescu SN. Staerk J, et al. Among authors: smith so. Blood. 2006 Mar 1;107(5):1864-71. doi: 10.1182/blood-2005-06-2600. Epub 2005 Oct 25. Blood. 2006. PMID: 16249382 Free PMC article.

7

Inhibitors of amyloid toxicity based on beta-sheet packing of Abeta40 and Abeta42.

Sato T, Kienlen-Campard P, Ahmed M, Liu W, Li H, Elliott JI, Aimoto S, Constantinescu SN, Octave JN, Smith SO. Sato T, et al. Among authors: smith so. Biochemistry. 2006 May 2;45(17):5503-16. doi: 10.1021/bi052485f. Biochemistry. 2006. PMID: 16634632 Free PMC article.

8

Structure of the membrane reconstituted transmembrane-juxtamembrane peptide EGFR(622-660) and its interaction with Ca2+/calmodulin.

Sato T, Pallavi P, Golebiewska U, McLaughlin S, Smith SO. Sato T, et al. Among authors: smith so. Biochemistry. 2006 Oct 24;45(42):12704-14. doi: 10.1021/bi061264m. Biochemistry. 2006. PMID: 17042488

9

Amyloidogenic processing but not amyloid precursor protein (APP) intracellular C-terminal domain production requires a precisely oriented APP dimer assembled by transmembrane GXXXG motifs.

Kienlen-Campard P, Tasiaux B, Van Hees J, Li M, Huysseune S, Sato T, Fei JZ, Aimoto S, Courtoy PJ, Smith SO, Constantinescu SN, Octave JN. Kienlen-Campard P, et al. Among authors: smith so. J Biol Chem. 2008 Mar 21;283(12):7733-44. doi: 10.1074/jbc.M707142200. Epub 2008 Jan 16. J Biol Chem. 2008. PMID: 18201969 Free PMC article.

10

A helix-to-coil transition at the epsilon-cut site in the transmembrane dimer of the amyloid precursor protein is required for proteolysis.

Sato T, Tang TC, Reubins G, Fei JZ, Fujimoto T, Kienlen-Campard P, Constantinescu SN, Octave JN, Aimoto S, Smith SO. Sato T, et al. Among authors: smith so. Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1421-6. doi: 10.1073/pnas.0812261106. Epub 2009 Jan 21. Proc Natl Acad Sci U S A. 2009. PMID: 19164538 Free PMC article.

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