Chen L - Search Results

1

Advances in targeting cell surface signalling molecules for immune modulation.

Yao S, Zhu Y, Chen L. Yao S, et al. Among authors: chen l. Nat Rev Drug Discov. 2013 Feb;12(2):130-46. doi: 10.1038/nrd3877. Nat Rev Drug Discov. 2013. PMID: 23370250 Free PMC article. Review.

2

Cancer therapeutic monoclonal antibodies targeting lymphocyte co-stimulatory pathways.

Zhu Y, Chen L. Zhu Y, et al. Among authors: chen l. Curr Opin Investig Drugs. 2003 Jun;4(6):691-5. Curr Opin Investig Drugs. 2003. PMID: 12901227 Review.

3

Genomic organization and expression analysis of B7-H4, an immune inhibitory molecule of the B7 family.

Choi IH, Zhu G, Sica GL, Strome SE, Cheville JC, Lau JS, Zhu Y, Flies DB, Tamada K, Chen L. Choi IH, et al. Among authors: chen l. J Immunol. 2003 Nov 1;171(9):4650-4. doi: 10.4049/jimmunol.171.9.4650. J Immunol. 2003. PMID: 14568939

4

Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gamma-induced upregulation of B7-H1 (CD274).

Lee SJ, Jang BC, Lee SW, Yang YI, Suh SI, Park YM, Oh S, Shin JG, Yao S, Chen L, Choi IH. Lee SJ, et al. Among authors: chen l. FEBS Lett. 2006 Feb 6;580(3):755-62. doi: 10.1016/j.febslet.2005.12.093. Epub 2006 Jan 9. FEBS Lett. 2006. PMID: 16413538 Free article.

5

Reviving exhausted T lymphocytes during chronic virus infection by B7-H1 blockade.

Yao S, Chen L. Yao S, et al. Among authors: chen l. Trends Mol Med. 2006 Jun;12(6):244-6. doi: 10.1016/j.molmed.2006.04.007. Epub 2006 May 2. Trends Mol Med. 2006. PMID: 16650803

6

CD137 stimulation delivers an antigen-independent growth signal for T lymphocytes with memory phenotype.

Zhu Y, Zhu G, Luo L, Flies AS, Chen L. Zhu Y, et al. Among authors: chen l. Blood. 2007 Jun 1;109(11):4882-9. doi: 10.1182/blood-2006-10-043463. Epub 2007 Jan 23. Blood. 2007. PMID: 17244673 Free PMC article.

7

Interaction between B7-H1 and PD-1 determines initiation and reversal of T-cell anergy.

Tsushima F, Yao S, Shin T, Flies A, Flies S, Xu H, Tamada K, Pardoll DM, Chen L. Tsushima F, et al. Among authors: chen l. Blood. 2007 Jul 1;110(1):180-5. doi: 10.1182/blood-2006-11-060087. Epub 2007 Feb 8. Blood. 2007. PMID: 17289811 Free PMC article.

8

Blocking of monocyte-associated B7-H1 (CD274) enhances HCV-specific T cell immunity in chronic hepatitis C infection.

Jeong HY, Lee YJ, Seo SK, Lee SW, Park SJ, Lee JN, Sohn HS, Yao S, Chen L, Choi I. Jeong HY, et al. Among authors: chen l. J Leukoc Biol. 2008 Mar;83(3):755-64. doi: 10.1189/jlb.0307168. Epub 2007 Dec 17. J Leukoc Biol. 2008. PMID: 18086898

9

B7-H1 is a ubiquitous antiapoptotic receptor on cancer cells.

Azuma T, Yao S, Zhu G, Flies AS, Flies SJ, Chen L. Azuma T, et al. Among authors: chen l. Blood. 2008 Apr 1;111(7):3635-43. doi: 10.1182/blood-2007-11-123141. Epub 2008 Jan 25. Blood. 2008. PMID: 18223165 Free PMC article.

10

B7-H4-deficient mice display augmented neutrophil-mediated innate immunity.

Zhu G, Augustine MM, Azuma T, Luo L, Yao S, Anand S, Rietz AC, Huang J, Xu H, Flies AS, Flies SJ, Tamada K, Colonna M, van Deursen JM, Chen L. Zhu G, et al. Among authors: chen l. Blood. 2009 Feb 19;113(8):1759-67. doi: 10.1182/blood-2008-01-133223. Epub 2008 Dec 24. Blood. 2009. PMID: 19109567 Free PMC article.

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