Fattah RJ - Search Results

1

Engineering anthrax toxin variants that exclusively form octamers and their application to targeting tumors.

Phillips DD, Fattah RJ, Crown D, Zhang Y, Liu S, Moayeri M, Fischer ER, Hansen BT, Ghirlando R, Nestorovich EM, Wein AN, Simons L, Leppla SH, Leysath CE. Phillips DD, et al. Among authors: fattah rj. J Biol Chem. 2013 Mar 29;288(13):9058-65. doi: 10.1074/jbc.M113.452110. Epub 2013 Feb 7. J Biol Chem. 2013. PMID: 23393143 Free PMC article.

2

Role of N-terminal amino acids in the potency of anthrax lethal factor.

Gupta PK, Moayeri M, Crown D, Fattah RJ, Leppla SH. Gupta PK, et al. Among authors: fattah rj. PLoS One. 2008 Sep 3;3(9):e3130. doi: 10.1371/journal.pone.0003130. PLoS One. 2008. PMID: 18769623 Free PMC article.

3

A Bacillus anthracis strain deleted for six proteases serves as an effective host for production of recombinant proteins.

Pomerantsev AP, Pomerantseva OM, Moayeri M, Fattah R, Tallant C, Leppla SH. Pomerantsev AP, et al. Protein Expr Purif. 2011 Nov;80(1):80-90. doi: 10.1016/j.pep.2011.05.016. Epub 2011 Aug 7. Protein Expr Purif. 2011. PMID: 21827967 Free PMC article.

4

Mouse monoclonal antibodies to anthrax edema factor protect against infection.

Leysath CE, Chen KH, Moayeri M, Crown D, Fattah R, Chen Z, Das SR, Purcell RH, Leppla SH. Leysath CE, et al. Infect Immun. 2011 Nov;79(11):4609-16. doi: 10.1128/IAI.05314-11. Epub 2011 Sep 12. Infect Immun. 2011. PMID: 21911463 Free PMC article.

5

Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome.

Levinsohn JL, Newman ZL, Hellmich KA, Fattah R, Getz MA, Liu S, Sastalla I, Leppla SH, Moayeri M. Levinsohn JL, et al. PLoS Pathog. 2012;8(3):e1002638. doi: 10.1371/journal.ppat.1002638. Epub 2012 Mar 29. PLoS Pathog. 2012. PMID: 22479187 Free PMC article.

6

Diphthamide modification on eukaryotic elongation factor 2 is needed to assure fidelity of mRNA translation and mouse development.

Liu S, Bachran C, Gupta P, Miller-Randolph S, Wang H, Crown D, Zhang Y, Wein AN, Singh R, Fattah R, Leppla SH. Liu S, et al. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13817-22. doi: 10.1073/pnas.1206933109. Epub 2012 Aug 6. Proc Natl Acad Sci U S A. 2012. PMID: 22869748 Free PMC article.

7

Anthrax lethal factor cleaves mouse nlrp1b in both toxin-sensitive and toxin-resistant macrophages.

Hellmich KA, Levinsohn JL, Fattah R, Newman ZL, Maier N, Sastalla I, Liu S, Leppla SH, Moayeri M. Hellmich KA, et al. PLoS One. 2012;7(11):e49741. doi: 10.1371/journal.pone.0049741. Epub 2012 Nov 12. PLoS One. 2012. PMID: 23152930 Free PMC article.

8

Recombinant expression and purification of a tumor-targeted toxin in Bacillus anthracis.

Bachran C, Abdelazim S, Fattah RJ, Liu S, Leppla SH. Bachran C, et al. Among authors: fattah rj. Biochem Biophys Res Commun. 2013 Jan 4;430(1):150-5. doi: 10.1016/j.bbrc.2012.11.055. Epub 2012 Nov 27. Biochem Biophys Res Commun. 2013. PMID: 23200832 Free PMC article.

9

Anthrax toxin-mediated delivery of the Pseudomonas exotoxin A enzymatic domain to the cytosol of tumor cells via cleavable ubiquitin fusions.

Bachran C, Morley T, Abdelazim S, Fattah RJ, Liu S, Leppla SH. Bachran C, et al. Among authors: fattah rj. mBio. 2013 Apr 30;4(3):e00201-13. doi: 10.1128/mBio.00201-13. mBio. 2013. PMID: 23631917 Free PMC article.

10

Key tissue targets responsible for anthrax-toxin-induced lethality.

Liu S, Zhang Y, Moayeri M, Liu J, Crown D, Fattah RJ, Wein AN, Yu ZX, Finkel T, Leppla SH. Liu S, et al. Among authors: fattah rj. Nature. 2013 Sep 5;501(7465):63-8. doi: 10.1038/nature12510. Epub 2013 Aug 28. Nature. 2013. PMID: 23995686 Free PMC article.

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