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First-in-human phase I trial of two schedules of OSI-930, a novel multikinase inhibitor, incorporating translational proof-of-mechanism studies.
Yap TA, Arkenau HT, Camidge DR, George S, Serkova NJ, Gwyther SJ, Spratlin JL, Lal R, Spicer J, Desouza NM, Leach MO, Chick J, Poondru S, Boinpally R, Gedrich R, Brock K, Stephens A, Eckhardt SG, Kaye SB, Demetri G, Scurr M. Yap TA, et al. Among authors: george s. Clin Cancer Res. 2013 Feb 15;19(4):909-19. doi: 10.1158/1078-0432.CCR-12-2258. Epub 2013 Feb 12. Clin Cancer Res. 2013. PMID: 23403628 Free PMC article. Clinical Trial.
CpG oligodeoxynucleotides alter lymphocyte and dendritic cell trafficking in humans.
Haining WN, Davies J, Kanzler H, Drury L, Brenn T, Evans J, Angelosanto J, Rivoli S, Russell K, George S, Sims P, Neuberg D, Li X, Kutok J, Morgan J, Wen P, Demetri G, Coffman RL, Nadler LM. Haining WN, et al. Among authors: george s. Clin Cancer Res. 2008 Sep 1;14(17):5626-34. doi: 10.1158/1078-0432.CCR-08-0526. Clin Cancer Res. 2008. PMID: 18765557 Clinical Trial.
Small molecule tyrosine kinase inhibitor and depression.
Quek R, Morgan JA, George S, Butrynski JE, Polson K, Meyer F, Demetri GD, Block SD. Quek R, et al. Among authors: george s. J Clin Oncol. 2009 Jan 10;27(2):312-3. doi: 10.1200/JCO.2008.19.7236. Epub 2008 Dec 8. J Clin Oncol. 2009. PMID: 19064960 No abstract available.
Multicenter phase II trial of sunitinib in the treatment of nongastrointestinal stromal tumor sarcomas.
George S, Merriam P, Maki RG, Van den Abbeele AD, Yap JT, Akhurst T, Harmon DC, Bhuchar G, O'Mara MM, D'Adamo DR, Morgan J, Schwartz GK, Wagner AJ, Butrynski JE, Demetri GD, Keohan ML. George S, et al. J Clin Oncol. 2009 Jul 1;27(19):3154-60. doi: 10.1200/JCO.2008.20.9890. Epub 2009 May 18. J Clin Oncol. 2009. PMID: 19451429 Free PMC article. Clinical Trial.
5,224 results